KEGG   Homo sapiens (human): 1981Help
Entry
1981              CDS       T01001                                 

Gene name
EIF4G1, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18
Definition
(RefSeq) eukaryotic translation initiation factor 4 gamma 1
  KO
K03260  
translation initiation factor 4G
Organism
hsa  Homo sapiens (human)
Pathway
RNA transport
Viral myocarditis
Module
eIF4F complex
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Genetic Information Processing
  Translation
   03013 RNA transport
    1981 (EIF4G1)
 Human Diseases
  Cardiovascular diseases
   05416 Viral myocarditis
    1981 (EIF4G1)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   Transport factors
    eIF4F and regulatory proteins
     1981 (EIF4G1)
   mRNA cycle factors
    Stress granule specific factors
     1981 (EIF4G1)
Translation factors [BR:hsa03012]
 Eukaryotic Type
  Initiation factors
   eIF-4
    1981 (EIF4G1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
3q27.1
AA seq 1599 aa AA seqDB search
MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS
SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY
PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI
RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI
IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES
TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE
PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE
PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG
EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA
VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ
WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI
NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL
MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM
KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR
KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK
FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN
QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV
QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS
NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV
VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ
PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK
EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY
EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL
GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS
EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD
VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF
YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN
NT seq 4800 nt NT seq  +upstreamnt  +downstreamnt
atgaacaaagctccacagtccacaggccccccacccgccccatcccccggactcccacag
ccagcgtttcccccggggcagacagcgccggtggtgttcagtacgccacaagcgacacaa
atgaacacgccttctcagccccgccagcacttctaccctagccgggcccagcccccgagc
agtgcagcctcccgagtgcagagtgcagcccctgcccgccctggcccagctgcccatgtc
taccctgctggatcccaagtaatgatgatcccttcccagatctcctacccagcctcccag
ggggcctactacatccctggacaggggcgttccacatacgttgtcccgacacagcagtac
cctgtgcagccaggagccccaggcttctatccaggtgcaagccctacagaatttgggacc
tacgctggcgcctactatccagcccaaggggtgcagcagtttcccactggcgtggccccc
gccccagttttgatgaaccagccaccccagattgctcccaagagggagcgtaagacgatc
cgaattcgagatccaaaccaaggaggaaaggatatcacagaggagatcatgtctggggcc
cgcactgcctccacacccacccctccccagacgggaggcggtctggagcctcaagctaat
ggggagacgccccaggttgctgtcattgtccggccagatgaccggtcacagggagcaatc
attgctgaccggccagggctgcctggcccagagcatagcccttcagaatcccagccttcg
tcgccttctccgaccccatcaccatccccagtcttggaaccggggtctgagcctaatctc
gcagtcctctctattcctggggacactatgacaactatacaaatgtctgtagaagaatca
acccccatctcccgtgaaactggggagccatatcgcctctctccagaacccactcctctc
gccgaacccatactggaagtagaagtgacacttagcaaaccggttccagaatctgagttt
tcttccagtcctctccaggctcccacccctttggcatctcacacagtggaaattcatgag
cctaatggcatggtcccatctgaagatctggaaccagaggtggagtcaagcccagagctt
gctcctcccccagcttgcccctccgaatcccctgtgcccattgctccaactgcccaacct
gaggaactgctcaacggagccccctcgccaccagctgtggacttaagcccagtcagtgag
ccagaggagcaggccaaggaggtgacagcatcaatggcgccccccaccatcccctctgct
actccagctacggctccttcagctacttccccagctcaggaggaggaaatggaagaagaa
gaagaagaggaagaaggagaagcaggagaagcaggagaagctgagagtgagaaaggagga
gaggaactgctccccccagagagtacccctattccagccaacttgtctcagaatttggag
gcagcagcagccactcaagtggcagtatctgtgccaaagaggagacggaaaattaaggag
ctaaataagaaggaggctgttggagaccttctggatgccttcaaggaggcgaacccggca
gtaccagaggtggaaaatcagcctcctgcaggcagcaatccaggcccagagtctgagggc
agtggtgtgcccccacgtcctgaggaagcagatgagacctgggactcaaaggaagacaaa
attcacaatgctgagaacatccagcccggggaacagaagtatgaatataagtcagatcag
tggaagcctctaaacctagaggagaaaaaacgttacgaccgtgagttcctgcttggtttt
cagttcatctttgccagtatgcagaagccagagggattgccacatatcagtgacgtggtg
ctggacaaggccaataaaacaccactgcggccactggatcccactagactacaaggcata
aattgtggcccagacttcactccatcctttgccaaccttggccggacaacccttagcacc
cgtgggcccccaaggggtgggccaggtggggagctgccccgtgggccggctggcctggga
ccccggcgctctcagcagggaccccgaaaagaaccacgcaagatcattgccacagtgtta
atgaccgaagatataaaactgaacaaagcagagaaagcctggaaacccagcagcaagcgg
acggcggctgataaggatcgaggggaagaagatgctgatggcagcaaaacccaggaccta
ttccgcagggtgcgctccatcctgaataaactgacaccccagatgttccagcagctgatg
aagcaagtgacgcagctggccatcgacaccgaggaacgcctcaaaggggtcattgacctc
atttttgagaaggccatttcagagcccaacttctctgtggcctatgccaacatgtgccgc
tgcctcatggcgctgaaagtgcccactacggaaaagccaacagtgactgtgaacttccga
aagctgttgttgaatcgatgtcagaaggagtttgagaaagacaaagatgatgatgaggtt
tttgagaagaagcaaaaagagatggatgaagctgctacggcagaggaacgaggacgcctg
aaggaagagctggaagaggctcgggacatagcccggcggcgctctttagggaatatcaag
tttattggagagttgttcaaactgaagatgttaacagaggcaataatgcatgactgtgtg
gtcaaactgcttaagaaccatgatgaagagtcccttgagtgcctttgtcgtctgctcacc
accattggcaaagacctggactttgaaaaagccaagccccgaatggatcagtatttcaac
cagatggaaaaaatcattaaagaaaagaagacgtcatcccgcatccgctttatgctgcag
gacgtgctggatctgcgagggagcaattgggtgccacgccgaggggatcagggtcccaag
accattgaccagatccataaggaggctgagatggaagaacatcgagagcacatcaaagtg
cagcagctcatggccaagggcagtgacaagcgtcggggcggtcctccaggccctcccatc
agccgtggacttccccttgtggatgatggtggctggaacacagttcccatcagcaaaggt
agccgccccattgacacctcacgactcaccaagatcaccaagcctggctccatcgattct
aacaaccagctctttgcacctggagggcgactgagctggggcaagggcagcagcggaggc
tcaggagccaagccctcagacgcagcatcagaagctgctcgcccagctactagtactttg
aatcgcttctcagcccttcaacaagcggtacccacagaaagcacagataatagacgtgtg
gtgcagaggagtagcttgagccgagaacgaggcgagaaagctggagaccgaggagaccgc
ctagagcggagtgaacggggaggggaccgtggggaccggcttgatcgtgcgcggacacct
gctaccaagcggagcttcagcaaggaagtggaggagcggagtagagaacggccctcccag
cctgaggggctgcgcaaggcagctagcctcacggaggatcgggaccgtgggcgggatgcc
gtgaagcgagaagctgccctacccccagtgagccccctgaaggcggctctctctgaggag
gagttagagaagaaatccaaggctatcattgaggaatatctccatctcaatgacatgaaa
gaggcagtccagtgcgtgcaggagctggcctcaccctccttgctcttcatctttgtacgg
catggtgtcgagtctacgctggagcgcagtgccattgctcgtgagcatatggggcagctg
ctgcaccagctgctctgtgctgggcatctgtctactgctcagtactaccaagggttgtat
gaaatcttggaattggctgaggacatggaaattgacatcccccacgtgtggctctaccta
gcggaactggtaacacccattctgcaggaaggtggggtgcccatgggggagctgttcagg
gagattacaaagcctctgagaccgttgggcaaagctgcttccctgttgctggagatcctg
ggcctcctgtgcaaaagcatgggtcctaaaaaggtggggacgctgtggcgagaagccggg
cttagctggaaggaatttctacctgaaggccaggacattggtgcattcgtcgctgaacag
aaggtggagtataccctgggagaggagtcggaagcccctggccagagggcactcccctcc
gaggagctgaacaggcagctggagaagctgctgaaggagggcagcagtaaccagcgggtg
ttcgactggatagaggccaacctgagtgagcagcagatagtatccaacacgttagttcga
gccctcatgacggctgtctgctattctgcaattatttttgagactcccctccgagtggac
gttgcagtgctgaaagcgcgagcgaagctgctgcagaaatacctgtgtgacgagcagaag
gagctacaggcgctctacgccctccaggcccttgtagtgaccttagaacagcctcccaac
ctgctgcggatgttctttgacgcactgtatgacgaggacgtggtgaaggaggatgccttc
tacagttgggagagtagcaaggaccccgctgagcagcagggcaagggtgtggcccttaaa
tctgtcacagccttcttcaagtggctccgtgaagcagaggaggagtctgaccacaactga

DBGET integrated database retrieval system