KEGG T01001: 2

Homo sapiens (human): 2

Entry

2 CDS T01001

Gene name

A2M, A2MD, CPAMD5, FWP007, S863-7

Definition

alpha-2-macroglobulin

Orthology

K03910

alpha-2-macroglobulin

Organism

hsa Homo sapiens (human)

Pathway

hsa04610

Complement and coagulation cascades

Class

Organismal Systems; Immune system; Complement and coagulation cascades [PATH:hsa04610]

SSDB

Motif

Pfam:

A2M_comp A2M_N_2 A2M A2M_recep A2M_N Thiol-ester_cl Prenyltrans_2 SVA Prenyltrans_1

Other DBs

NCBI-GI:

66932947

NCBI-GeneID:

OMIM:

103950

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2P9R 4ACQ 1BV8

Position

12p13.31

AA seq 1474 aa
MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTV
SASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTV
MVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQS
FQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIIT
ILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCF
YQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFR
QGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLT
VRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHY
ILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARL
LIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAV
DQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYINGITYTPVSS
TNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARL
VHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGI
SSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVE
KEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVI
KPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQ
NTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKH
YDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCF
RSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDH
GSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQ
APSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHA
LSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEG
CVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAI
VDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVR
DLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA

NT seq 4425 nt +upstreamnt +downstreamnt
atggggaagaacaaactccttcatccaagtctggttcttctcctcttggtcctcctgccc
acagacgcctcagtctctggaaaaccgcagtatatggttctggtcccctccctgctccac
actgagaccactgagaagggctgtgtccttctgagctacctgaatgagacagtgactgta
agtgcttccttggagtctgtcaggggaaacaggagcctcttcactgacctggaggcggag
aatgacgtactccactgtgtcgccttcgctgtcccaaagtcttcatccaatgaggaggta
atgttcctcactgtccaagtgaaaggaccaacccaagaatttaagaagcggaccacagtg
atggttaagaacgaggacagtctggtctttgtccagacagacaaatcaatctacaaacca
gggcagacagtgaaatttcgtgttgtctccatggatgaaaactttcaccccctgaatgag
ttgattccactagtatacattcaggatcccaaaggaaatcgcatcgcacaatggcagagt
ttccagttagagggtggcctcaagcaattttcttttcccctctcatcagagcccttccag
ggctcctacaaggtggtggtacagaagaaatcaggtggaaggacagagcaccctttcacc
gtggaggaatttgttcttcccaagtttgaagtacaagtaacagtgccaaagataatcacc
atcttggaagaagagatgaatgtatcagtgtgtggcctatacacatatgggaagcctgtc
cctggacatgtgactgtgagcatttgcagaaagtatagtgacgcttccgactgccacggt
gaagattcacaggctttctgtgagaaattcagtggacagctaaacagccatggctgcttc
tatcagcaagtaaaaaccaaggtcttccagctgaagaggaaggagtatgaaatgaaactt
cacactgaggcccagatccaagaagaaggaacagtggtggaattgactggaaggcagtcc
agtgaaatcacaagaaccataaccaaactctcatttgtgaaagtggactcacactttcga
cagggaattcccttctttgggcaggtgcgcctagtagatgggaaaggcgtccctatacca
aataaagtcatattcatcagaggaaatgaagcaaactattactccaatgctaccacggat
gagcatggccttgtacagttctctatcaacaccaccaatgttatgggtacctctcttact
gttagggtcaattacaaggatcgtagtccctgttacggctaccagtgggtgtcagaagaa
cacgaagaggcacatcacactgcttatcttgtgttctccccaagcaagagctttgtccac
cttgagcccatgtctcatgaactaccctgtggccatactcagacagtccaggcacattat
attctgaatggaggcaccctgctggggctgaagaagctctccttctattatctgataatg
gcaaagggaggcattgtccgaactgggactcatggactgcttgtgaagcaggaagacatg
aagggccatttttccatctcaatccctgtgaagtcagacattgctcctgtcgctcggttg
ctcatctatgctgttttacctaccggggacgtgattggggattctgcaaaatatgatgtt
gaaaattgtctggccaacaaggtggatttgagcttcagcccatcacaaagtctcccagcc
tcacacgcccacctgcgagtcacagcggctcctcagtccgtctgcgccctccgtgctgtg
gaccaaagcgtgctgctcatgaagcctgatgctgagctctcggcgtcctcggtttacaac
ctgctaccagaaaaggacctcactggcttccctgggcctttgaatgaccaggacgatgaa
gactgcatcaatcgtcataatgtctatattaatggaatcacatatactccagtatcaagt
acaaatgaaaaggatatgtacagcttcctagaggacatgggcttaaaggcattcaccaac
tcaaagattcgtaaacccaaaatgtgtccacagcttcaacagtatgaaatgcatggacct
gaaggtctacgtgtaggtttttatgagtcagatgtaatgggaagaggccatgcacgcctg
gtgcatgttgaagagcctcacacggagaccgtacgaaagtacttccctgagacatggatc
tgggatttggtggtggtaaactcagcaggtgtggctgaggtaggagtaacagtccctgac
accatcaccgagtggaaggcaggggccttctgcctgtctgaagatgctggacttggtatc
tcttccactgcctctctccgagccttccagcccttctttgtggagctcacaatgccttac
tctgtgattcgtggagaggccttcacactcaaggccacggtcctaaactaccttcccaaa
tgcatccgggtcagtgtgcagctggaagcctctcccgccttcctagctgtcccagtggag
aaggaacaagcgcctcactgcatctgtgcaaacgggcggcaaactgtgtcctgggcagta
accccaaagtcattaggaaatgtgaatttcactgtgagcgcagaggcactagagtctcaa
gagctgtgtgggactgaggtgccttcagttcctgaacacggaaggaaagacacagtcatc
aagcctctgttggttgaacctgaaggactagagaaggaaacaacattcaactccctactt
tgtccatcaggtggtgaggtttctgaagaattatccctgaaactgccaccaaatgtggta
gaagaatctgcccgagcttctgtctcagttttgggagacatattaggctctgccatgcaa
aacacacaaaatcttctccagatgccctatggctgtggagagcagaatatggtcctcttt
gctcctaacatctatgtactggattatctaaatgaaacacagcagcttactccagagatc
aagtccaaggccattggctatctcaacactggttaccagagacagttgaactacaaacac
tatgatggctcctacagcacctttggggagcgatatggcaggaaccagggcaacacctgg
ctcacagcctttgttctgaagacttttgcccaagctcgagcctacatcttcatcgatgaa
gcacacattacccaagccctcatatggctctcccagaggcagaaggacaatggctgtttc
aggagctctgggtcactgctcaacaatgccataaagggaggagtagaagatgaagtgacc
ctctccgcctatatcaccatcgcccttctggagattcctctcacagtcactcaccctgtt
gtccgcaatgccctgttttgcctggagtcagcctggaagacagcacaagaaggggaccat
ggcagccatgtatataccaaagcactgctggcctatgcttttgccctggcaggtaaccag
gacaagaggaaggaagtactcaagtcacttaatgaggaagctgtgaagaaagacaactct
gtccattgggagcgccctcagaaacccaaggcaccagtggggcatttttacgaaccccag
gctccctctgctgaggtggagatgacatcctatgtgctcctcgcttatctcacggcccag
ccagccccaacctcggaggacctgacctctgcaaccaacatcgtgaagtggatcacgaag
cagcagaatgcccagggcggtttctcctccacccaggacacagtggtggctctccatgct
ctgtccaaatatggagcagccacatttaccaggactgggaaggctgcacaggtgactatc
cagtcttcagggacattttccagcaaattccaagtggacaacaacaaccgcctgttactg
cagcaggtctcattgccagagctgcctggggaatacagcatgaaagtgacaggagaagga
tgtgtctacctccagacatccttgaaatacaatattctcccagaaaaggaagagttcccc
tttgctttaggagtgcagactctgcctcaaacttgtgatgaacccaaagcccacaccagc
ttccaaatctccctaagtgtcagttacacagggagccgctctgcctccaacatggcgatc
gttgatgtgaagatggtctctggcttcattcccctgaagccaacagtgaaaatgcttgaa
agatctaaccatgtgagccggacagaagtcagcagcaaccatgtcttgatttaccttgat
aaggtgtcaaatcagacactgagcttgttcttcacggttctgcaagatgtcccagtaaga
gatctgaaaccagccatagtgaaagtctatgattactacgagacggatgagtttgcaatt
gctgagtacaatgctccttgcagcaaagatcttggaaatgcttga

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (23)   
   RefSeq(nuc) (1)   
   GenBank (11)   
   EMBL (11)   
3D Structure (3)   
   PDB (3)   
Protein domain (9)   
   Pfam (9)   
All databases (58)   

Download RDF

DBGET integrated database retrieval system