KEGG   Homo sapiens (human): 2186
Entry
2186              CDS       T01001                                 
Symbol
BPTF, FAC1, FALZ, NEDDFL, NURF301
Name
(RefSeq) bromodomain PHD finger transcription factor
  KO
K11728  nucleosome-remodeling factor subunit BPTF
Organism
hsa  Homo sapiens (human)
Pathway
hsa03082  ATP-dependent chromatin remodeling
Disease
H02460  Neurodevelopmental disorder with dysmorphic facies and skeletal anomalies
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03082 ATP-dependent chromatin remodeling
    2186 (BPTF)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    2186 (BPTF)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Chromatin remodeling factors
   NuRF complex
    2186 (BPTF)
   NuRF complex (fruit fly)
    2186 (BPTF)
SSDB
Motif
Pfam: Bromodomain DDT PHD WSD WHIM1 PHD_5 Arc_PepC_II zf-HC5HC2H
Other DBs
NCBI-GeneID: 2186
NCBI-ProteinID: NP_872579
OMIM: 601819
HGNC: 3581
Ensembl: ENSG00000171634
UniProt: Q12830
Structure
Position
17:67825503..67984378
AA seq 2920 aa
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAP
KTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRA
VNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPN
EHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDT
SNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPP
LEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIE
EDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNK
ARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQ
SLEKDSDDKTPDDDPEQGKSEVGDFKSEKSNGELSESPGAGKGASGSTRIITRLRNPDSK
LSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEG
KYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTL
RLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIW
RESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEY
RVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKK
IKIEPDSEKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDD
DMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLE
KIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGC
SESDSSVLRMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRG
QEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKS
TNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFR
TREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIK
LKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKV
NNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDS
LETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSND
FIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENC
AKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSK
EYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREV
PYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKA
PPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRK
GLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRL
EQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQ
NKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTS
GSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQ
PVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHG
GNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATT
ASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQ
PQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSP
VRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSS
TQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQ
SGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIE
IKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILD
KIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIE
VQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLS
TPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCD
RCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAH
KMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYY
NPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS
NT seq 8763 nt   +upstreamnt  +downstreamnt
atgaggggccggcggggcaggccgcccaagcagcccgcggctcccgctgcggagcgctgc
gccccggccccgccgccaccgccgccgccgcccacgtccggacccatcggggggctccgc
tcgcggcaccgcggcagcagccggggcaggtgggccgccgcccaggctgaggtggcgccc
aagacgcggctgagctcgcccagggggggcagcagtagccggaggaagccgccgccgccg
ccgccggccccccccagcaccagcgccccgggccggggggggcgaggaggcgggggcggc
aggacggggggcgggggcggcggcggccacctggcccggaccaccgcggcccggagggcc
gtcaacaaagtggtgtacgatgaccacgagagcgaggaggaggaggaagaggaggacatg
gtctccgaggaggaggaggaggaggacggcgacgccgaggagacccaggattctgaggac
gacgaggaggatgagatggaagaggacgacgatgactccgattatccggaggagatggaa
gacgacgacgacgacgccagttactgcacggaaagcagcttcaggagccatagtacctac
agcagcactccaggtaggcgaaaaccaagagtacatcggcctcgttctcctatattggaa
gaaaaagacatcccgccccttgaatttcccaagtcctctgaggatttaatggtgcctaat
gagcatataatgaatgtcattgccatttacgaggtactgcggaactttggcactgttttg
agattatctccttttcgctttgaggacttttgtgcagctctggtgagccaagagcagtgc
acactcatggcagagatgcatgttgtgcttttgaaagcagttctgcgtgaagaagacact
tccaatactacctttggacctgctgatctgaaagatagcgttaattccacactgtatttc
atagatgggatgacgtggccagaggtgctgcgggtgtactgtgagagtgataaggagtac
catcacgttcttccttaccaagaggcagaggactacccatatggaccagtagagaacaag
atcaaagttctacagtttctagtcgatcagtttcttacaacaaatattgctcgagaggaa
ttgatgtctgaaggggtgatacagtatgatgaccattgtagggtttgtcacaaacttggg
gatttgctttgctgtgagacatgttcagcagtataccatttggaatgtgtgaagccacct
cttgaggaggtgccagaggacgagtggcagtgtgaagtctgtgtagcacacaaggtgcct
ggtgtgactgactgtgttgctgaaatccaaaaaaataaaccatatattcgacatgaacct
attggatatgatagaagtcggaggaaatactggttcttgaaccgaagactcataatagaa
gaagatacagaaaatgaaaatgaaaagaaaatttggtattacagcacaaaggtccaactt
gcagaattaattgactgtctagacaaagattattgggaagcagaactctgcaaaattcta
gaagaaatgcgtgaagaaatccaccgacacatggacataactgaagacctgaccaataag
gctcggggcagtaacaaatcctttctggcggcagctaatgaagaaattttggaatccata
agagccaaaaagggagacattgataatgttaaaagcccagaagaaacagaaaaagacaag
aatgagactgagaatgactctaaagatgctgagaaaaacagagaagaatttgaagaccag
tcccttgaaaaagacagtgacgacaaaacaccagatgatgaccctgagcaaggaaaatct
gaggtaggtgatttcaaatcggagaagtccaacggggagctaagtgaatctcctggagct
ggaaaaggagcatctggctcaactcgaatcatcaccagattgcggaatccagatagcaaa
cttagtcagctgaagagccagcaggtggcagccgctgcacatgaagcaaataaattattt
aaggagggcaaagaggtactggtagttaactctcaaggagaaatttcacggttgagcacc
aaaaaggaagtgatcatgaaaggaaatatcaacaattattttaaattgggtcaagaaggg
aagtatcgcgtctaccacaatcaatactccaccaattcatttgctttgaataagcaccag
cacagagaagaccatgataagagaaggcatcttgcacataagttctgtctgactccagca
ggagagttcaaatggaacggttctgtccatgggtccaaagttcttaccatatctactctg
agactgactatcacccaattagaaaacaacatcccttcatcctttcttcatcccaactgg
gcatcacatagggcaaattggatcaaggcagttcagatgtgtagcaaacccagagaattt
gcattggctttagccattttggagtgtgcagttaaaccagttgtgatgctaccaatatgg
cgagaatctttaggacataccaggttacaccggatgacatcaattgaaagagaagaaaag
gagaaagtcaaaaaaaaagagaagaaacaggaagaagaagaaacgatgcagcaagcgaca
tgggtaaaatacacatttccagttaagcatcaggtttggaaacaaaaaggtgaagagtac
agagtgacaggatatggtggttggagctggattagtaaaactcatgtttataggtttgtt
cctaaattgccaggcaatactaatgtgaattacagaaagtcgttagaaggaaccaaaaat
aatatggatgaaaatatggatgagtcagataaaagaaaatgttcacgaagtccaaaaaaa
ataaaaatagagcctgattctgaaaaagatgaggtaaaaggttcagatgctgcaaaagga
gcagaccaaaatgaaatggatatctcaaagattactgagaagaaggaccaagatgtgaag
gagctcttagattctgacagtgataaaccctgcaaggaagaaccaatggaagtagacgat
gacatgaaaacagagtcacatgtaaattgtcaggagagttctcaagtagatgtggtcaat
gttagtgagggttttcatctaaggactagttacaaaaagaaaacaaaatcatccaaacta
gatggacttcttgaaaggagaattaaacagtttacactggaagaaaaacagcgactcgaa
aaaatcaagttggagggtggaattaagggtataggaaagacttctacaaattcttcaaaa
aatctctctgaatcaccagtaataacgaaagcaaaagaagggtgtcagagtgactcgatg
agacaagaacagagcccaaatgcaaataatgatcaacctgaggacttgattcagggatgt
tcagaaagtgattcctcagttcttagaatgagtgatcctagtcataccacaaacaaactt
tatccaaaagatcgagtgttagatgatgtctccattcggagcccagaaacaaaatgtccg
aaacaaaattccattgaaaatgacatagaagaaaaagtctctgaccttgccagtagaggc
caggaacccagtaagagtaaaacaaaaggaaatgattttttcatcgatgactctaaacta
gccagtgcagatgatattggtactttgatctgtaagaacaaaaaaccgctcatacaggag
gaaagtgacaccattgtttcttcttccaagagtgctttacattcatcagtgcctaaaagt
accaatgacagagatgccacacctctgtcaagagcaatggactttgaaggaaaactggga
tgtgactctgaatctaatagcactttggaaaatagttctgataccgtgtctattcaggat
agcagtgaagaagatatgattgttcagaatagcaatgaaagcatttctgaacagttcaga
actcgagaacaagatgttgaagtcttggagccgttaaagtgtgagttggtttctggtgag
tccactggaaactgtgaggacaggctgccggtcaaggggactgaagcaaatggtaaaaaa
ccaagtcagcagaagaaattagaggagagaccagttaataaatgtagtgatcaaataaag
ctaaaaaataccactgacaaaaagaataatgaaaatcgagagtctgaaaagaaaggacag
agaacaagtacatttcaaataaatggaaaagataataaacccaaaatatatttgaaaggt
gaatgcttgaaagaaatttctgagagtagagtagtaagtggtaatgttgaaccaaaggtt
aataatataaataaaataatccctgagaatgatattaaatcattgactgttaaagaatct
gctataaggccattcattaatggtgatgtcatcatggaagattttaatgaaagaaacagc
tccgaaacaaaatcgcatttgctgagttcttcagatgctgaaggtaactaccgagatagc
cttgagaccctgccatcaaccaaagagtctgacagtacacagacgaccacaccctcagca
tcttgtccagaaagcaattcagttaatcaggtagaagatatggaaatagaaacctcagaa
gttaagaaagttacttcatcacctattacttctgaagaggaatctaatctcagtaatgac
tttattgatgaaaatggtctgcccatcaacaaaaatgaaaatgtcaatggagaatctaaa
agaaaaaccgtcatcacagaagtcaccacgatgacctccacagtggccacagaatcaaaa
actgtgatcaaggtagaaaaaggcgataagcaaactgtggtttcttccacagaaaattgt
gcaaaatccactgtcacaaccaccactacaacagtgaccaagctttccacaccctccaca
ggcggcagtgtggacatcatctctgtaaaggagcagagcaaaaccgtggtcaccacgaca
gtgacagactccctgaccaccacgggaggcacactggttacatctatgactgtgagcaaa
gagtattccacacgagacaaagtgaaactgatgaaattttcaagaccaaagaagactcgt
tcaggtacagctctgccatcctatagaaaatttgttaccaagagcagcaagaagagcatt
tttgttttgcctaatgatgacttaaaaaagttggcccgaaaaggaggaatccgagaggtc
ccttattttaattacaatgcaaaacctgctttggatatatggccatatccttctcctaga
ccgacctttggcatcacttggaggtatagacttcagacagtaaagtccttagctggagtg
agcctgatgttacggttactgtgggcaagtttgagatgggatgatatggcggccaaggct
cctccaggaggagggactacacggacagaaacatccgaaactgaaatcacaacaacagaa
ataattaagaggagagatgttggtccttatggcattcgatctgaatattgtatcaggaaa
atcatttgtcccattggagttccagaaacaccaaaagaaacgcctacacctcagaggaaa
ggccttcgatcaagtgcactgcggccaaagagaccagaaacgcccaagcaaactggccct
gttattattgaaacctgggtagcagaagaagaactggaattgtgggagatcagggcattt
gctgagagagtggagaaagaaaaggcacaagcagttgagcaacaggctaagaaacgactg
gagcagcagaagccgacagtgattgcaacttccactacttccccaacaagcagtacaacc
agcaccatctctccagcacagaaggttatggtggcccccataagtggctcagttacaact
ggaaccaaaatggtactaactactaaagttggatctccagctacagtaacattccaacaa
aacaagaactttcatcaaacctttgctacatgggttaagcaaggccagtcaaattcaggc
gttgttcaagtacagcagaaagtcctgggtatcattccatcaagtacaggtaccagtcag
caaacctttacttcattccagcccaggacagcaacagtcacaattaggcccaatacctca
ggctctggaggaaccacaagcaattcacaagtaatcacagggcctcagattcgccctggt
atgaccgtgattagaacaccactccaacagtcaacactaggaaaggcaattattcgaaca
cctgtgatggtacagccaggtgctcctcagcaagtgatgactcaaatcatcagggggcag
cctgtctccactgcagtctccgcccctaacacggtttcctcaacacctgggcagaaaagc
ttaacttcagcaacgtccacttcaaatatacagtcttcagcctcacaaccccctcgcccc
caacaaggacaagtgaagctcaccatggctcaacttactcagttaacacagggccacggt
ggcaatcaaggtttgacagtagtaattcaaggacaaggtcaaactactggacagttgcag
ttgatacctcaaggggtgactgtactcccaggcccaggccagcagctaatgcaagctgca
atgccaaatggtactgttcagcgattcctctttaccccattggcaacaacagccaccaca
gccagcaccaccaccaccactgtttccacgacagcagcaggtacaggtgaacaaaggcag
agtaaactgtcaccccagatgcaggtacatcaagacaaaaccctgccaccagctcagtca
tcaagtgtgggtccagcagaagcccagccacagactgctcagccttcagctcagccccag
ccccaaacccagccccagtccccagctcagcctgaagttcagactcagcctgaagttcag
acccaaacaactgtttcatcccatgtcccttctgaagcacaacccacccacgcacagtca
tccaagccccaagttgcagcacagtctcagcctcaaagtaatgtccaaggacagtctcct
gttcgtgtccaaagtccatcacagactcgaatacgtccatcaactccatcccaactgtct
cctggacaacaatcccaggttcagactacaacctcacaaccgattccaattcaaccacat
acatctcttcagataccttcccaaggccagccacagtcacaaccccaggtacagtcttca
actcaaactctttcatcaggacaaactttaaatcaagttactgtttcatccccatcccgt
cctcagctacaaatacagcagccacagccccaagtcattgctgtgcctcagctgcaacaa
caagtccaggttctctctcagatccagtcacaggttgtggctcagatacaggctcagcaa
agtggtgtgccccagcaaatcaaactccagttacctatccaaattcagcaaagcagtgct
gtgcagactcaccagattcagaatgtggttacagtgcaggcagccagtgtgcaagagcag
ttgcaaagggttcagcaactcagggatcagcagcaaaagaagaaacagcaacagatagaa
attaagcgtgaacacaccctccaagcttctaatcaaagtgaaatcattcagaaacaggtg
gtgatgaagcataatgctgtaatagaacatttaaaacagaaaaagagcatgactccagct
gaaagagaagagaatcaaagaatgattgtctgtaaccaggtgatgaagtatattttggat
aagatagataaagaagaaaaacaggcagcaaaaaaacggaagcgtgaagagagtgtggag
cagaaacgtagcaagcagaatgccactaagctgtcagctctgctcttcaagcacaaagag
cagctcagagccgagatcctgaagaagagagcactcctggacaaggatctgcaaattgaa
gtgcaggaagagctgaagagagacctgaaaattaagaaagaaaaagacctgatgcagttg
gctcaggccacagcagtagctgcaccctgccccccagtgacaccagctcctccagcccct
ccagcccctccaccttcacctccccctccacctgctgtgcaacacacaggccttctgtcc
acgcccaccttacctgctgcttcccagaagaggaagcgggaagaggaaaaagactccagc
tcaaagtccaagaaaaagaaaatgatctctactacctcaaaggaaactaagaaggacaca
aagctttactgtatctgtaaaacgccttatgatgaatctaaattttatattggctgtgat
cggtgtcagaattggtaccatgggcgctgcgttggcatcttgcaaagtgaggcagagctc
attgatgagtatgtctgtccacagtgccagtcaacagaggatgccatgacagtgctcacg
ccactaacagagaaggattatgaggggttgaagagggtgctccgttccttacaggcccat
aagatggcctggcctttccttgaaccagtagaccctaatgatgcaccagattattatggt
gttattaaggaacctatggaccttgccaccatggaagaaagagtacaaagacgatattat
gaaaagctgacggaatttgtggcagatatgaccaaaatttttgataactgtcgttactac
aatccaagtgactccccattttaccagtgtgcagaagttctcgaatcattctttgtacag
aaattgaaaggcttcaaagctagcaggtctcataacaacaaactgcagtctacagcttct
taa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (73)   
   KEGG ORTHOLOGY (1)   
   RefGene (64)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (100)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (98)   
DNA sequence (140)   
   RefSeq(nuc) (98)   
   GenBank (21)   
   EMBL (21)   
3D Structure (43)   
   PDB (43)   
Protein domain (8)   
   Pfam (8)   
All databases (371)   

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