KEGG   Homo sapiens (human): 2203Help
Entry
2203              CDS       T01001                                 

Gene name
FBP1, FBP
Definition
fructose-1,6-bisphosphatase 1 (EC:3.1.3.11)
Orthology
K03841  
fructose-1,6-bisphosphatase I [EC:3.1.3.11]
Organism
hsa  Homo sapiens (human)
Pathway
Glycolysis / Gluconeogenesis
Pentose phosphate pathway
Fructose and mannose metabolism
Metabolic pathways
Carbon metabolism
AMPK signaling pathway
Insulin signaling pathway
Module
Gluconeogenesis, oxaloacetate => fructose-6P
Disease
H00114  
Fructose-1,6-bisphosphatase deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    2203 (FBP1)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    2203 (FBP1)
   00030 Pentose phosphate pathway
    2203 (FBP1)
   00051 Fructose and mannose metabolism
    2203 (FBP1)
 Environmental Information Processing
  Signal transduction
   04152 AMPK signaling pathway
    2203 (FBP1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    2203 (FBP1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.11  fructose-bisphosphatase
     2203 (FBP1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   2203 (FBP1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
9q22.3
AA seq 338 aa AA seqDB search
MADQAPFDTDVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGI
AGSTNVTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDP
LDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDC
GVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAP
YGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGK
EAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHSAQ
NT seq 1017 nt NT seq  +upstreamnt  +downstreamnt
atggctgaccaggcgcccttcgacacggacgtcaacaccctgacccgcttcgtcatggag
gagggcaggaaggcccgcggcacgggcgagttgacccagctgctcaactcgctctgcaca
gcagtcaaagccatctcttcggcggtgcgcaaggcgggcatcgcgcacctctatggcatt
gctggttctaccaacgtgacaggtgatcaagttaagaagctggacgtcctctccaacgac
ctggttatgaacatgttaaagtcatcctttgccacgtgtgttctcgtgtcagaagaagat
aaacacgccatcatagtggaaccggagaaaaggggtaaatatgtggtctgttttgatccc
cttgatggatcttccaacatcgattgccttgtgtccgttggaaccatttttggcatctat
agaaagaaatcaactgatgagccttctgagaaggatgctctgcaaccaggccggaacctg
gtggcagccggctacgcactgtatggcagtgccaccatgctggtccttgccatggactgt
ggggtcaactgcttcatgctggacccggccatcggggagttcattttggtggacaaggat
gtgaagataaaaaagaaaggtaaaatctacagccttaacgagggctacgccagggacttt
gaccctgccgtcactgagtacatccagaggaagaagttccccccagataattcagctcct
tatggggcccggtatgtgggctccatggtggctgatgttcatcgcactctggtctacgga
gggatatttctgtaccccgctaacaagaagagccccaatggaaagctgagactgctgtac
gaatgcaaccccatggcctacgtcatggagaaggctgggggaatggccaccactgggaag
gaggccgtgttagacgtcattcccacagacattcaccagagggcgccggtgatcttggga
tcccccgacgacgtgctcgagttcctgaaggtgtatgagaagcactctgcccagtga

DBGET integrated database retrieval system