KEGG   Homo sapiens (human): 23382
Entry
23382             CDS       T01001                                 
Symbol
AHCYL2, ADOHCYASE3, IRBIT2
Name
(RefSeq) adenosylhomocysteinase like 2
  KO
K01251  adenosylhomocysteinase [EC:3.13.2.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00270  Cysteine and methionine metabolism
hsa01100  Metabolic pathways
Module
hsa_M00035  Methionine degradation
Network
nt06030  Methionine metabolism
  Element
N01607  Methionine degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    23382 (AHCYL2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    23382 (AHCYL2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    23382 (AHCYL2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.13  Acting on carbon-sulfur bonds
   3.13.2  Thioether and trialkylsulfonium hydrolases
    3.13.2.1  adenosylhomocysteinase
     23382 (AHCYL2)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     23382 (AHCYL2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   23382 (AHCYL2)
SSDB
Motif
Pfam: AdoHcyase AdoHcyase_NAD 2-Hacid_dh_C Shikimate_DH THF_DHG_CYH_C NAD_binding_7 IlvN TrkA_N AlaDh_PNT_C SR-25
Other DBs
NCBI-GeneID: 23382
NCBI-ProteinID: NP_056143
OMIM: 616520
HGNC: 22204
Ensembl: ENSG00000158467
UniProt: Q96HN2
Structure
Position
7:129225030..129430211
AA seq 611 aa
MSVQVVSAAAAAKVPEVELKDLSPSEAESQLGLSTAAVGAMAPPAGGGDPEAPAPAAERP
PVPGPGSGPAAALSPAAGKVPQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVK
KQIQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNS
KGSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTA
VLMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVE
GWQPNMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVN
DSVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYV
TEIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGH
SNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITA
TTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNK
NGPFKPNYYRY
NT seq 1836 nt   +upstreamnt  +downstreamnt
atgtcggtgcaggttgtgtcagccgcggctgccgccaaggtgcctgaggtggagctgaag
gacctgagcccctccgaggcggagtcgcaactaggactgagcacggccgccgtgggcgcc
atggcccccccggcgggcggtggagaccctgaggctccagctcccgccgcggagcggccc
ccggtccccggcccgggctcggggcccgccgccgctctcagccccgccgccgggaaggtg
cctcaggcgtcggccatgaagcggagcgacccacatcaccagcaccagcggcaccgcgac
ggcggcgaggccctggtcagccccgacggcaccgtcaccgaggcgccgcgcacagtcaag
aagcagatccagtttgctgaccagaagcaagaattcaacaaacgtcccaccaaaattgga
cgtcgctctttgtctcgttccatttctcagtcatctactgacagctacagctcagcggct
tcatatacagatagctctgatgatgagacatcgcccagggacaagcagcaaaagaactct
aagggaagcagtgacttctgtgttaagaacatcaaacaggcagagtttggacgaagagaa
attgaaattgctgaacaagaaatgcctgcattgatggctttgaggaagagagctcaagga
gaaaagcctttggctggagccaaaatcgtgggttgcacacacatcactgctcagactgct
gtgcttatggaaactctgggtgctctgggggcccagtgccgatgggctgcctgcaacatc
tattccactctcaatgaagtggctgctgctctagcagaaagtggatttcctgtttttgcc
tggaagggagagtcagaagatgacttttggtggtgtatcgatagatgtgtgaatgtggag
ggctggcagccaaacatgatcttggatgatggaggggatcttacccactggatttataaa
aagtatcccaacatgtttaagaaaatcaagggcatagtagaggagagtgttactggagtt
cacaggctgtaccaactgtccaaagctgggaagctgtgtgttccagccatgaatgtcaat
gactcagtcaccaaacagaaatttgacaacctctactgttgccgtgaatcaattcttgat
ggacttaaaaggacaacagacatgatgtttggtggaaagcaagtggtagtctgtggctat
ggagaggtggggaaagggtgctgtgctgccctgaaagccatgggctccattgtgtatgta
actgaaattgaccccatctgtgccctgcaagcctgtatggatggatttcgactggtgaaa
ttaaatgaggtcatccgacaagtggacattgttattacctgtacaggtaacaagaatgtg
gtaaccagagagcacttggaccgtatgaagaatagctgcatcgtttgtaacatgggacat
tccaacacagagattgacgtggcgagtctgcggacaccagaactgacctgggagcgagtg
agatctcaagttgaccatgtgatatggcctgatggcaagaggatagtactgctggcagag
ggccgcctgctgaaccttagctgctccacagtgcctacatttgtgctctcaatcactgct
actactcaggctcttgccttgatagagctttacaatgctcctgagggtcgctataagcag
gatgtctacctgttgcccaagaagatggatgagtatgtggccagcctacacctgcctacc
tttgatgcccacttgacagagctgacagatgaacaggccaagtatctgggactcaacaag
aatgggcccttcaagcctaattactacaggtattaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
Protein sequence (25)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (23)   
DNA sequence (42)   
   RefSeq(nuc) (24)   
   GenBank (9)   
   EMBL (9)   
3D Structure (1)   
   PDB (1)   
Protein domain (10)   
   Pfam (10)   
All databases (122)   

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