KEGG T01001: 23411

Homo sapiens (human): 23411

Entry

23411 CDS T01001

Gene name

SIRT1, SIR2L1

Definition

sirtuin 1

Orthology

K11411

NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]

Organism

hsa Homo sapiens (human)

Pathway

hsa05031

Amphetamine addiction

Class

Human Diseases; Substance dependence; Amphetamine addiction [PATH:hsa05031]

SSDB

Motif

Pfam:

SIR2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

4I5I

Position

10q21.3

AA seq 452 aa
MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAG
IQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFG
ENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFD
VELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVS
EDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQM
ENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGA
EVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGA
GFGTDGDDQEAINEAISVKQEVTDMNYPSNKS

NT seq 1359 nt +upstreamnt +downstreamnt
atgtttgatattgaatatttcagaaaagatccaagaccattcttcaagtttgcaaaggaa
atatatcctggacaattccagccatctctctgtcacaaattcatagccttgtcagataag
gaaggaaaactacttcgcaactatacccagaacatagacacgctggaacaggttgcggga
atccaaaggataattcagtgtcatggttcctttgcaacagcatcttgcctgatttgtaaa
tacaaagttgactgtgaagctgtacgaggagatatttttaatcaggtagttcctcgatgt
cctaggtgcccagctgatgaaccgcttgctatcatgaaaccagagattgtgttttttggt
gaaaatttaccagaacagtttcatagagccatgaagtatgacaaagatgaagttgacctc
ctcattgttattgggtcttccctcaaagtaagaccagtagcactaattccaagttccata
ccccatgaagtgcctcagatattaattaatagagaacctttgcctcatctgcattttgat
gtagagcttcttggagactgtgatgtcataattaatgaattgtgtcataggttaggtggt
gaatatgccaaactttgctgtaaccctgtaaagctttcagaaattactgaaaaacctcca
cgaacacaaaaagaattggcttatttgtcagagttgccacccacacctcttcatgtttca
gaagactcaagttcaccagaaagaacttcaccaccagattcttcagtgattgtcacactt
ttagaccaagcagctaagagtaatgatgatttagatgtgtctgaatcaaaaggttgtatg
gaagaaaaaccacaggaagtacaaacttctaggaatgttgaaagtattgctgaacagatg
gaaaatccggatttgaagaatgttggttctagtactggggagaaaaatgaaagaacttca
gtggctggaacagtgagaaaatgctggcctaatagagtggcaaaggagcagattagtagg
cggcttgatggtaatcagtatctgtttttgccaccaaatcgttacattttccatggcgct
gaggtatattcagactctgaagatgacgtcttatcctctagttcttgtggcagtaacagt
gatagtgggacatgccagagtccaagtttagaagaacccatggaggatgaaagtgaaatt
gaagaattctacaatggcttagaagatgagcctgatgttccagagagagctggaggagct
ggatttgggactgatggagatgatcaagaggcaattaatgaagctatatctgtgaaacag
gaagtaacagacatgaactatccatcaaacaaatcatag

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (3)   
   RefSeq(pep) (2)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
3D Structure (1)   
   PDB (1)   
Protein domain (1)   
   Pfam (1)   
All databases (50)   

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