KEGG   Homo sapiens (human): 250
Entry
250               CDS       T01001                                 
Symbol
ALPP, ALP, ALPI, IAP, PALP, PLAP, PLAP-1
Name
(RefSeq) alkaline phosphatase, placental
  KO
K01077  alkaline phosphatase [EC:3.1.3.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00730  Thiamine metabolism
hsa00790  Folate biosynthesis
hsa01100  Metabolic pathways
hsa01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    250 (ALPP)
   00790 Folate biosynthesis
    250 (ALPP)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    250 (ALPP)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
    250 (ALPP)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.1  alkaline phosphatase
     250 (ALPP)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   250 (ALPP)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Enzymes
  250 (ALPP)
SSDB
Motif
Pfam: Alk_phosphatase Metalloenzyme
Other DBs
NCBI-GeneID: 250
NCBI-ProteinID: NP_001623
OMIM: 171800
HGNC: 439
Ensembl: ENSG00000163283
UniProt: P05187 B2R7C7
Structure
Position
2:232378751..232382889
AA seq 535 aa
MLGPCMLLLLLLLGLRLQLSLGIIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLII
FLGDGMGVSTVTAARILKGQKKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATA
YLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAG
TYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYP
DDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEI
HRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAI
ERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPG
YVLKDGARPDVTESESGSPEYRQQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFI
AHVMAFAACLEPYTACDLAPPAGTTDAAHPGRSVVPALLPLLAGTLLLLETATAP
NT seq 1608 nt   +upstreamnt  +downstreamnt
atgctggggccctgcatgctgctgctgctgctgctgctgggcctgaggctacagctctcc
ctgggcatcatcccagttgaggaggagaacccggacttctggaaccgcgaggcagccgag
gccctgggtgccgccaagaagctgcagcctgcacagacagccgccaagaacctcatcatc
ttcctgggcgatgggatgggggtgtctacggtgacagctgccaggatcctaaaagggcag
aagaaggacaaactggggcctgagatacccctggccatggaccgcttcccatatgtggct
ctgtccaagacatacaatgtagacaaacatgtgccagacagtggagccacagccacggcc
tacctgtgcggggtcaagggcaacttccagaccattggcttgagtgcagccgcccgcttt
aaccagtgcaacacgacacgcggcaacgaggtcatctccgtgatgaatcgggccaagaaa
gcagggaagtcagtgggagtggtaaccaccacacgagtgcagcacgcctcgccagccggc
acctacgcccacacggtgaaccgcaactggtactcggacgccgacgtgcctgcctccgcc
cgccaggaggggtgccaggacatcgctacgcagctcatctccaacatggacattgacgtg
atcctaggtggaggccgaaagtacatgtttcgcatgggaaccccagaccctgagtaccca
gatgactacagccaaggtgggaccaggctggacgggaagaatctggtgcaggaatggctg
gcgaagcgccagggtgcccggtatgtgtggaaccgcactgagctcatgcaggcttccctg
gacccgtctgtgacccatctcatgggtctctttgagcctggagacatgaaatacgagatc
caccgagactccacactggacccctccctgatggagatgacagaggctgccctgcgcctg
ctgagcaggaacccccgcggcttcttcctcttcgtggagggtggtcgcatcgaccatggt
catcatgaaagcagggcttaccgggcactgactgagacgatcatgttcgacgacgccatt
gagagggcgggccagctcaccagcgaggaggacacgctgagcctcgtcactgccgaccac
tcccacgtcttctccttcggaggctaccccctgcgagggagctccatcttcgggctggcc
cctggcaaggcccgggacaggaaggcctacacggtcctcctatacggaaacggtccaggc
tatgtgctcaaggacggcgcccggccggatgttaccgagagcgagagcgggagccccgag
tatcggcagcagtcagcagtgcccctggacgaagagacccacgcaggcgaggacgtggcg
gtgttcgcgcgcggcccgcaggcgcacctggttcacggcgtgcaggagcagaccttcata
gcgcacgtcatggccttcgccgcctgcctggagccctacaccgcctgcgacctggcgccc
cccgccggcaccaccgacgccgcgcacccggggcggtccgtggtccccgcgttgcttcct
ctgctggccgggaccctgctgctgctggagacggccactgctccctga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (23)   
   RefSeq(nuc) (1)   
   GenBank (11)   
   EMBL (11)   
3D Structure (8)   
   PDB (8)   
Protein domain (2)   
   Pfam (2)   
All databases (71)   

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