KEGG   Homo sapiens (human): 2565Help
Entry
2565              CDS       T01001                                 

Gene name
GABRG1
Definition
gamma-aminobutyric acid (GABA) A receptor, gamma 1
Orthology
K05186  
gmma-aminobutyric acid receptor subunit gamma
Organism
hsa  Homo sapiens (human)
Pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Drug target
Hexobarbital: 
Thiopental: 
Propofol: 
Methylphenobarbital: 
Phenobarbital: 
Clonazepam: 
Aminobutyric acid: 
Diazepam: 
Chlordiazepoxide: 
Medazepam: 
Oxazepam: 
Potassium clorazepate: 
Lorazepam: 
Adinazolam: 
Bromazepam: 
Clobazam: 
Prazepam: 
Alprazolam: 
Nordazepam: 
Fludiazepam: 
Ethyl loflazepate: 
Etizolam: 
Clotiazepam: 
Cloxazolam: 
Tofisopam: 
Meprobamate: 
Pentobarbital: 
Amobarbital: 
Barbital: 
Secobarbital: 
Flurazepam: 
Nitrazepam: 
Flunitrazepam: 
Estazolam: 
Triazolam: 
Lormetazepam: 
Temazepam: 
Midazolam: 
Brotizolam: 
Quazepam: 
Loprazolam: 
Glutethimide: 
Zopiclone: 
Zolpidem: 
Eszopiclone: 
Methaqualone: 
Pentetrazol: 
Flumazenil: 
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    2565 (GABRG1)
 Organismal Systems
  Nervous system
   04727 GABAergic synapse
    2565 (GABRG1)
   04723 Retrograde endocannabinoid signaling
    2565 (GABRG1)
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    2565 (GABRG1)
   05033 Nicotine addiction
    2565 (GABRG1)
Ion channels [BR:hsa04040]
 Cys-loop superfamily
  GABA-A
   2565 (GABRG1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
4p12
AA seq 465 aa AA seqDB search
MGPLKAFLFSPFLLRSQSRGVRLVFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIH
EGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWF
DSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTL
RLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAF
VGLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVP
ARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN
QKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCCFE
DCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL
NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt
atgggtcctttgaaagcttttctcttctccccttttcttctgcggagtcaaagtagaggg
gtgaggttggtcttcttgttactgaccctgcatttgggaaactgtgttgataaggcagat
gatgaagatgatgaggatttaacggtgaacaaaacctgggtcttggccccaaaaattcat
gaaggagatatcacacaaattctgaattcattgcttcaaggctatgacaataaacttcgt
ccagatataggagtgaggcccacagtaattgaaactgatgtttatgtaaacagcattgga
ccagttgatccaattaatatggaatatacaatagatataatttttgcccaaacctggttt
gacagtcgtttaaaattcaatagtaccatgaaagtgcttatgcttaacagtaatatggtt
ggaaaaatttggattcctgacactttcttcagaaactcaagaaaatctgatgctcactgg
ataacaactcctaatcgtctgcttcgaatttggaatgatggacgagttctgtatactcta
agattgacaattaatgcagaatgttatcttcagcttcataactttcccatggatgaacat
tcctgtccactggaattttcaagctatggataccctaaaaatgaaattgagtataagtgg
aaaaagccctccgtagaagtggctgatcctaaatactggagattatatcagtttgcattt
gtagggttacggaactcaactgaaatcactcacacgatctctggggattatgttatcatg
acaattttttttgacctgagcagaagaatgggatatttcactattcagacctacattcca
tgcattctgacagttgttctttcttgggtgtctttttggatcaataaagatgcagtgcct
gcaagaacatcgttgggtatcactacagttctgactatgacaaccctgagtacaattgcc
aggaagtctttacctaaggtttcttatgtgactgcgatggatctctttgtttctgtttgt
ttcatttttgtttttgcagccttgatggaatatggaaccttgcattattttaccagcaac
caaaaaggaaagactgctactaaagacagaaagctaaaaaataaagcctcgatgactcct
ggtctccatcctggatccactctgattccaatgaataatatttctgtgccgcaagaagat
gattatgggtatcagtgtttggagggcaaagattgtgccagcttcttctgttgctttgaa
gactgcagaacaggatcttggagggaaggaaggatacacatacgcattgccaaaattgac
tcttattctagaatatttttcccaaccgcttttgccctgttcaacttggtttattgggtt
ggctatctttacttataa

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