KEGG   Homo sapiens (human): 25902Help
Entry
25902             CDS       T01001                                 

Gene name
MTHFD1L, FTHFSDC1, MTC1THFS, dJ292B18.2
Definition
(RefSeq) methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (EC:6.3.4.3)
  KO
K13402  
monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3]
Organism
hsa  Homo sapiens (human)
Pathway
One carbon pool by folate
Metabolic pathways
Module
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    25902 (MTHFD1L)
Enzymes [BR:hsa01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     25902 (MTHFD1L)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
6q25.1
AA seq 978 aa AA seqDB search
MGTRLPLVLRQLRRPPQPPGPPRRLRVPCRASSGGGGGGGGGREGLLGQRRPQDGQARSS
CSPGGRTPAARDSIVREVIQNSKEVLSLLQEKNPAFKPVLAIIQAGDDNLMQEINQNLAE
EAGLNITHICLPPDSSEAEIIDEILKINEDTRVHGLALQISENLFSNKVLNALKPEKDVD
GVTDINLGKLVRGDAHECFVSPVAKAVIELLEKSGVNLDGKKILVVGAHGSLEAALQCLF
QRKGSMTMSIQWKTRQLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNCSHDFLSGKV
GCGSPRIHFGGLIEEDDVILLAAALRIQNMVSSGRRWLREQQHRRWRLHCLKLQPLSPVP
SDIEISRGQTPKAVDVLAKEIGLLADEIEIYGKSKAKVRLSVLERLKDQADGKYVLVAGI
TPTPLGEGKSTVTIGLVQALTAHLNVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEE
FNLHLTGDIHAITAANNLLAAAIDTRILHENTQTDKALYNRLVPLVNGVREFSEIQLARL
KKLGINKTDPSTLTEEEVSKFARLDIDPSTITWQRVLDTNDRFLRKITIGQGNTEKGHYR
QAQFDIAVASEIMAVLALTDSLADMKARLGRMVVASDKSGQPVTADDLGVTGALTVLMKD
AIKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGEEGFVVTEAGFGADIGM
EKFFNIKCRASGLVPNVVVLVATVRALKMHGGGPSVTAGVPLKKEYTEENIQLVADGCCN
LQKQIQITQLFGVPVVVALNVFKTDTRAEIDLVCELAKRAGAFDAVPCYHWSVGGKGSVD
LARAVREAASKRSRFQFLYDVQVPIVDKIRTIAQAVYGAKDIELSPEAQAKIDRYTQQGF
GNLPICMAKTHLSLSHQPDKKGVPRDFILPISDVRASIGAGFIYPLVGTMSTMPGLPTRP
CFYDIDLDTETEQVKGLF
NT seq 2937 nt NT seq  +upstreamnt  +downstreamnt
atgggcacgcgtctgccgctcgtcctgcgccagctccgccgcccgccccagcccccgggc
cctccgcgccgcctccgtgtgccctgtcgcgctagcagcggcggcggcggaggcggcggc
ggtggccgggagggcctgcttggacagcggcggccgcaggatggccaggcccggagcagc
tgcagccccggcggccgaacgcccgcggcgcgggactccatcgtcagagaagtcattcag
aattcaaaagaagttctaagtttattgcaagaaaaaaaccctgccttcaagccggttctt
gcaattatccaggcaggtgacgacaacttgatgcaggaaatcaaccagaatttggctgag
gaggctggtctgaacatcactcacatttgcctccctccagatagcagtgaagccgagatt
atagatgaaatcttaaagatcaatgaagataccagagtacatggccttgcccttcagatc
tctgagaacttgtttagcaacaaagtcctcaatgccttgaaaccagaaaaagatgtggat
ggagtaacagacataaacctggggaagctggtgcgaggggatgcccatgaatgttttgtt
tcacctgttgccaaagctgtaattgaacttcttgaaaaatcaggtgtcaacctagatgga
aagaagattttggtagtgggggcccatgggtctttggaagctgctctacaatgcctgttc
cagagaaaagggtccatgacaatgagcatccagtggaaaacacgccagcttcaaagcaag
cttcacgaggctgacattgtggtcctaggctcacctaagccagaagagattccccttact
tggatacaaccaggaactactgttctcaactgctcccatgacttcctgtcagggaaggtt
gggtgtggctctccaagaatacattttggtggactcattgaggaagatgatgtgattctc
cttgctgcagctctgcgaattcagaacatggtcagtagtggaaggagatggcttcgtgaa
cagcagcacaggcggtggagacttcactgcttgaaacttcagcctctctcccctgtgcca
agtgacattgagatttcaagaggacaaactccaaaagctgtggatgtccttgccaaggag
attggattgcttgcagatgaaattgaaatctatggcaaaagcaaagccaaagtacgtttg
tccgtgctagaaaggttaaaggatcaagcagatggaaaatacgtcttagttgctgggatc
acacccacccctcttggagaagggaagagcacagtcaccatcgggcttgtgcaggctctg
accgcacacctgaatgtcaactcctttgcctgcttgaggcagccttcccaaggaccgacg
tttggagtgaaaggaggagccgcgggtggtggatatgcccaggtcatccccatggaggag
ttcaaccttcacttgactggagacatccacgccatcaccgctgccaataacttgctggct
gccgccatcgacacgaggattcttcatgaaaacacgcaaacagataaggctctgtataat
cggctggttcctttagtgaatggtgtcagagaattttcagaaattcagcttgctcggcta
aaaaaactgggaataaataagactgatccgagcacactgacagaagaggaagtgagtaaa
tttgcccgtctcgacatcgacccatctaccatcacgtggcagagagtattggatacaaat
gaccgatttctacgaaaaataaccatcgggcagggaaacacagagaagggccattaccgg
caggcgcagtttgacatcgcagtggccagcgagatcatggcggtgctggccctgacggac
agcctcgcagacatgaaggcacggctgggaaggatggtggtggccagtgacaaaagcggg
cagcctgtgacagcagatgatttgggggtgacaggtgctttgacagttttgatgaaagat
gcaataaaaccaaacctgatgcagaccctggaagggacacctgtgttcgtgcatgcgggc
ccttttgctaacattgctcacggcaactcttcagtgttggctgataaaattgccctgaaa
ctggttggtgaagaaggatttgtagtgaccgaagctggctttggtgctgacatcggaatg
gagaaattcttcaacatcaagtgccgagcttccggcttggtgcccaacgtggttgtgtta
gtggcaacggtgcgagctctgaagatgcatggaggcgggccaagtgtaacggctggtgtt
cctcttaagaaagaatatacagaggagaacatccagctggtggcagacggctgctgtaac
ctccagaagcaaattcagatcactcagctctttggggttcccgttgtggtggctctgaat
gtcttcaagaccgacacccgcgctgagattgacttggtgtgtgagcttgcaaagcgggct
ggtgcctttgatgcagtcccctgctatcactggtccgttggtggaaaaggatcggtggac
ttggctcgggctgtgagagaggctgcgagtaaaagaagccgattccagttcctgtatgat
gttcaggttccaattgtggacaagataaggaccattgctcaggctgtctatggagccaaa
gatattgaactctctcctgaggcacaagccaaaatagatcgttacactcaacagggtttt
ggaaatttgcccatctgcatggcaaagacccacctttctctatctcaccaacctgacaaa
aaaggtgtgccaagggacttcatcttacctatcagtgacgtccgggccagcataggcgct
gggttcatttaccctttggtcggaacgatgagcaccatgccaggactgcccacccggccc
tgcttttatgacatagatcttgataccgaaacagaacaagttaaaggcttgttctaa

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