KEGG   Homo sapiens (human): 283455
Entry
283455            CDS       T01001                                 
Symbol
KSR2
Name
(RefSeq) kinase suppressor of ras 2
  KO
K18529  kinase suppressor of Ras 2 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    283455 (KSR2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    283455 (KSR2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     283455 (KSR2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: TKL group
  RAF family [OT]
   283455 (KSR2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SAM_KSR1_N SAM_KSR1 C1_1 RIO1 Kdo Kinase-like FTA2
Other DBs
NCBI-GeneID: 283455
NCBI-ProteinID: NP_775869
OMIM: 610737
HGNC: 18610
Ensembl: ENSG00000171435
UniProt: Q6VAB6
Structure
Position
12:complement(117453012..117968990)
AA seq 950 aa
MDEENMTKSEEQQPLSLQKALQQCELVQNMIDLSISNLEGLRTKCATSNDLTQKEIRTLE
SKLVKYFSRQLSCKKKVALQERNAELDGFPQLRHWFRIVDVRKEVLEEISPGQLSLEDLL
EMTDEQVCETVEKYGANREECARLNASLSCLRNVHMSGGNLSKQDWTIQWPTTETGKENN
PVCPPEPTPWIRTHLSQSPRVPSKCVQHYCHTSPTPGAPVYTHVDRLTVDAYPGLCPPPP
LESGHRSLPPSPRQRHAVRTPPRTPNIVTTVTPPGTPPMRKKNKLKPPGTPPPSSRKLIH
LIPGFTALHRSKSHEFQLGHRVDEAHTPKAKKKSKPLNLKIHSSVGSCENIPSQQRSPLL
SERSLRSFFVGHAPFLPSTPPVHTEANFSANTLSVPRWSPQIPRRDLGNSIKHRFSTKYW
MSQTCTVCGKGMLFGLKCKNCKLKCHNKCTKEAPPCHLLIIHRGDPARLVRTESVPCDIN
NPLRKPPRYSDLHISQTLPKTNKINKDHIPVPYQPDSSSNPSSTTSSTPSSPAPPLPPSA
TPPSPLHPSPQCTRQQKNFNLPASHYYKYKQQFIFPDVVPVPETPTRAPQVILHPVTSNP
ILEGNPLLQIEVEPTSENEEVHDEAEESEDDFEEMNLSLLSARSFPRKASQTSIFLQEWD
IPFEQLEIGELIGKGRFGQVYHGRWHGEVAIRLIDIERDNEDQLKAFKREVMAYRQTRHE
NVVLFMGACMSPPHLAIITSLCKGRTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLHAK
GILHKDLKSKNVFYDNGKVVITDFGLFSISGVLQAGRREDKLRIQNGWLCHLAPEIIRQL
SPDTEEDKLPFSKHSDVFALGTIWYELHAREWPFKTQPAEAIIWQMGTGMKPNLSQIGMG
KEISDILLFCWAFEQEERPTFTKLMDMLEKLPKRNRRLSHPGHFWKSAEL
NT seq 2853 nt   +upstreamnt  +downstreamnt
atggatgaggaaaacatgacgaaaagcgaggagcagcagcctctgagtttgcaaaaagcc
ttacagcagtgcgaactggtccaaaacatgatagacttgagcatctccaacctggaaggg
cttaggaccaaatgtgctacctccaacgacctcacacaaaaagaaatccggaccctggag
agcaagctggtgaagtacttcagccggcagctgtcctgcaaaaagaaggtagccttgcag
gagcgcaacgcggagctggacggcttcccccagctacggcactggttccgaatcgtcgat
gtgcgcaaggaggtcctggaggaaatctcccccggccagctgagcctggaggacctcttg
gagatgacggatgaacaggtgtgcgagactgtggagaaatacggagccaaccgggaggag
tgtgcccgcctcaacgcctccctctcctgcctcaggaatgtccacatgtcaggaggcaac
ctttccaaacaagactggaccatccagtggcccacgacagagacggggaaggagaacaat
cccgtgtgccccccggagcccaccccgtggatccgcacccatctctcccagagccccagg
gtcccgtccaagtgcgtccagcactattgtcacaccagccccactcccggggcccctgtg
tacacccacgtggacaggcttaccgtggacgcctacccgggcttgtgcccgcccccgcca
ctggagtcgggccaccgttccctgcccccatcgccccggcagcggcacgcggtccgcacc
ccgccgcgcacccccaacatcgtcaccaccgtgaccccgccgggcacgccgcccatgagg
aagaagaacaagctgaagcccccggggaccccaccgccctcctcccgaaaactgatacac
ttgatcccgggattcaccgcgctgcatcggagcaaatcccacgagttccagctggggcac
cgcgtggacgaggcccacacgcccaaagccaagaagaagagcaaacccttgaacctcaag
atccacagcagcgtaggcagctgcgagaacatcccctctcagcagcgctccccgctgctg
tccgagcgctccctccgctccttctttgtgggacacgcacctttcctgccttccacccct
cctgttcacactgaggccaacttctctgcaaacacactgtcagtgccacgctggtccccg
cagatccctcgcagagatctcggcaactccatcaagcacaggttttccaccaagtactgg
atgtctcagacgtgcacagtctgtgggaaagggatgctttttggcctcaagtgtaaaaac
tgcaagttaaagtgccacaacaaatgcaccaaagaagccccaccctgtcatcttctgatc
atccaccgaggagatccagcaaggttagtccggacagagtccgttccgtgtgacatcaac
aaccctctacggaagccacctcgctattcagacctgcacatcagtcagacgctccccaaa
accaacaaaatcaacaaggaccacatccctgtcccttaccagccagactccagcagcaac
ccctcctccacgacgtcctccacgccctcctcgccagcaccccccctccctcctagtgcc
acgccgccttctcccctacacccttccccacagtgcacacggcagcagaagaacttcaac
ctgccagcatcccactactacaaatacaagcagcagttcatcttcccagatgtggtgccg
gtgccggagacgccgacccgggcgccccaggtcatcctgcatccggtgacctcgaatcca
atcttggaaggaaatccattacttcaaattgaagtggagccaacgtcggagaatgaagag
gtccatgatgaggccgaagagtcagaggatgacttcgaggagatgaacctgtccctcctc
tcggcccggagcttcccacgcaaggccagccagaccagcatcttccttcaggagtgggac
atcccctttgagcagctggagatcggcgagctcattggaaagggccgctttgggcaagtg
taccacggccgctggcatggcgaggtggccatccggctgattgacattgagagggacaac
gaggaccagctcaaggccttcaagcgggaggtgatggcctacaggcagacacggcatgag
aacgtggtgcttttcatgggtgcctgcatgagcccgcctcacctggccatcatcaccagc
ctctgtaagggacggacgctctattccgttgtgagggatgccaaaatcgttttggatgtc
aacaaaaccaggcagattgctcaagaaattgtgaagggcatgggctacctccacgccaag
ggaatcctacacaaggacctcaagtcaaagaacgtcttctatgacaacggcaaagtggtc
atcacggactttggactcttcagcatttctggggtgctgcaggctggcaggcgggaggac
aaactgcgcatccagaatggctggctatgccacctggcaccagagatcatccgccagctg
tcccccgacacagaggaggataagctccccttctccaagcactctgacgtctttgccctt
ggcacaatctggtatgaactccacgccagggaatggcctttcaagacccaaccagcagag
gcaataatctggcaaatgggcacaggcatgaaacccaacctcagccagattggcatggga
aaagaaatctcggacattcttctcttctgctgggcctttgaacaagaagagagacctacc
ttcaccaagctcatggacatgctggagaaactgccaaagcgaaaccgtcgcctgtctcac
cctggacatttctggaagtctgcagagctgtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (17)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (15)   
DNA sequence (31)   
   RefSeq(nuc) (15)   
   GenBank (8)   
   EMBL (8)   
3D Structure (9)   
   PDB (9)   
Protein domain (9)   
   Pfam (9)   
All databases (95)   

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