KEGG T01001: 2876

Homo sapiens (human): 2876

Entry

2876 CDS T01001

Gene name

GPX1, GPXD, GSHPX1

Definition

glutathione peroxidase 1 (EC:1.11.1.9)

Orthology

K00432

glutathione peroxidase [EC:1.11.1.9]

Organism

hsa Homo sapiens (human)

Pathway

hsa00480	Glutathione metabolism
hsa00590	Arachidonic acid metabolism
hsa05014	Amyotrophic lateral sclerosis (ALS)
hsa05016	Huntington's disease

Disease

H00668

Anemia due to disorders of glutathione metabolism

Class

Metabolism; Lipid metabolism; Arachidonic acid metabolism [PATH:hsa00590]
Metabolism; Metabolism of other amino acids; Glutathione metabolism [PATH:hsa00480]
Human Diseases; Neurodegenerative diseases; Amyotrophic lateral sclerosis (ALS) [PATH:hsa05014]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:hsa05016]

SSDB

Motif

Pfam:

GSHPx Redoxin

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2F8A

Position

3p21.3

AA seq 203 aa
MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMN
ELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGA
GAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYS
RRFQTIDIEPDIEALLSQGPSCA

NT seq 612 nt +upstreamnt +downstreamnt
atgtgtgctgctcggctagcggcggcggcggcggcggcccagtcggtgtatgccttctcg
gcgcgcccgctggccggcggggagcctgtgagcctgggctccctgcggggcaaggtacta
cttatcgagaatgtggcgtccctctgaggcaccacggtccgggactacacccagatgaac
gagctgcagcggcgcctcggaccccggggcctggtggtgctcggcttcccgtgcaaccag
tttgggcatcaggagaacgccaagaacgaagagattctgaattccctcaagtacgtccgg
cctggtggtgggttcgagcccaacttcatgctcttcgagaagtgcgaggtgaacggtgcg
ggggcgcaccctctcttcgccttcctgcgggaggccctgccagctcccagcgacgacgcc
accgcgcttatgaccgaccccaagctcatcacctggtctccggtgtgtcgcaacgatgtt
gcctggaactttgagaagttcctggtgggccctgacggtgtgcccctacgcaggtacagc
cgccgcttccagaccattgacatcgagcctgacatcgaagccctgctgtctcaagggccc
agctgtgcctag

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (20)   
   RefSeq(nuc) (2)   
   GenBank (9)   
   EMBL (9)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (64)   

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