KEGG   Homo sapiens (human): 2885Help
Entry
2885              CDS       T01001                                 

Gene name
GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2
Definition
growth factor receptor-bound protein 2
Orthology
K04364  
growth factor receptor-binding protein 2
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Osteoclast differentiation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Hepatitis B
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    2885 (GRB2)
   04010 MAPK signaling pathway
    2885 (GRB2)
   04012 ErbB signaling pathway
    2885 (GRB2)
   04630 Jak-STAT signaling pathway
    2885 (GRB2)
   04068 FoxO signaling pathway
    2885 (GRB2)
   04151 PI3K-Akt signaling pathway
    2885 (GRB2)
 Cellular Processes
  Cell communication
   04510 Focal adhesion
    2885 (GRB2)
   04540 Gap junction
    2885 (GRB2)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    2885 (GRB2)
   04660 T cell receptor signaling pathway
    2885 (GRB2)
   04662 B cell receptor signaling pathway
    2885 (GRB2)
   04664 Fc epsilon RI signaling pathway
    2885 (GRB2)
   04062 Chemokine signaling pathway
    2885 (GRB2)
  Endocrine system
   04910 Insulin signaling pathway
    2885 (GRB2)
   04912 GnRH signaling pathway
    2885 (GRB2)
   04915 Estrogen signaling pathway
    2885 (GRB2)
   04917 Prolactin signaling pathway
    2885 (GRB2)
  Nervous system
   04722 Neurotrophin signaling pathway
    2885 (GRB2)
  Development
   04320 Dorso-ventral axis formation
    2885 (GRB2)
   04380 Osteoclast differentiation
    2885 (GRB2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    2885 (GRB2)
   05206 MicroRNAs in cancer
    2885 (GRB2)
   05205 Proteoglycans in cancer
    2885 (GRB2)
   05203 Viral carcinogenesis
    2885 (GRB2)
   05214 Glioma
    2885 (GRB2)
   05221 Acute myeloid leukemia
    2885 (GRB2)
   05220 Chronic myeloid leukemia
    2885 (GRB2)
   05211 Renal cell carcinoma
    2885 (GRB2)
   05215 Prostate cancer
    2885 (GRB2)
   05213 Endometrial cancer
    2885 (GRB2)
   05223 Non-small cell lung cancer
    2885 (GRB2)
  Substance dependence
   05034 Alcoholism
    2885 (GRB2)
  Infectious diseases
   05161 Hepatitis B
    2885 (GRB2)
   05160 Hepatitis C
    2885 (GRB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
17q24-q25
AA seq 217 aa AA seqDB search
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt NT seq  +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaacgaagaatgtgatcagaactggtacaaggcagag
cttaatggaaaagacggcttcattcccaagaactacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcacgat
ggggcctttcttatccgagagagtgagagcgctcctggggacttctccctctctgtcaag
tttggaaacgatgtgcagcacttcaaggtgctccgagatggagccgggaagtacttcctc
tgggtggtgaagttcaattctttgaatgagctggtggattatcacagatctacatctgtc
tccagaaaccagcagatattcctgcgggacatagaacaggtgccacagcagccgacatac
gtccaggccctctttgactttgatccccaggaggatggagagctgggcttccgccgggga
gattttatccatgtcatggataactcagaccccaactggtggaaaggagcttgccacggg
cagaccggcatgtttccccgcaattatgtcacccccgtgaaccggaacgtctaa

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