KEGG   Homo sapiens (human): 3108Help
Entry
3108              CDS       T01001                                 

Gene name
HLA-DMA, D6S222E, DMA, HLADM, RING6
Definition
major histocompatibility complex, class II, DM alpha
Orthology
K06752  
major histocompatibility complex, class II
Organism
hsa  Homo sapiens (human)
Pathway
Phagosome
Cell adhesion molecules (CAMs)
Antigen processing and presentation
Intestinal immune network for IgA production
Type I diabetes mellitus
Leishmaniasis
Toxoplasmosis
Staphylococcus aureus infection
Tuberculosis
Influenza A
HTLV-I infection
Herpes simplex infection
Asthma
Autoimmune thyroid disease
Inflammatory bowel disease (IBD)
Systemic lupus erythematosus
Rheumatoid arthritis
Allograft rejection
Graft-versus-host disease
Viral myocarditis
Disease
H00083  
Allograft rejection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    3108 (HLA-DMA)
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    3108 (HLA-DMA)
 Organismal Systems
  Immune system
   04612 Antigen processing and presentation
    3108 (HLA-DMA)
   04672 Intestinal immune network for IgA production
    3108 (HLA-DMA)
 Human Diseases
  Immune diseases
   05310 Asthma
    3108 (HLA-DMA)
   05322 Systemic lupus erythematosus
    3108 (HLA-DMA)
   05323 Rheumatoid arthritis
    3108 (HLA-DMA)
   05320 Autoimmune thyroid disease
    3108 (HLA-DMA)
   05321 Inflammatiory bowel disease (IBD)
    3108 (HLA-DMA)
   05330 Allograft rejection
    3108 (HLA-DMA)
   05332 Graft-versus-host disease
    3108 (HLA-DMA)
  Cardiovascular diseases
   05416 Viral myocarditis
    3108 (HLA-DMA)
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    3108 (HLA-DMA)
  Infectious diseases
   05150 Staphylococcus aureus infection
    3108 (HLA-DMA)
   05152 Tuberculosis
    3108 (HLA-DMA)
   05166 HTLV-I infection
    3108 (HLA-DMA)
   05164 Influenza A
    3108 (HLA-DMA)
   05168 Herpes simplex infection
    3108 (HLA-DMA)
   05145 Toxoplasmosis
    3108 (HLA-DMA)
   05140 Leishmaniasis
    3108 (HLA-DMA)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   3108 (HLA-DMA)
  Exosomal proteins of epithelial cells
   3108 (HLA-DMA)
  Exosomal proteins of breast milk
   3108 (HLA-DMA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
6p21.3
AA seq 261 aa AA seqDB search
MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLS
EAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKI
PVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVD
GLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLG
VLGIIVGIVLIIYFRKPCSGD
NT seq 786 nt NT seq  +upstreamnt  +downstreamnt
atgggtcatgaacagaaccaaggagctgcgctgctacagatgttaccacttctgtggctg
ctaccccactcctgggccgtccctgaagctcctactccaatgtggccagatgacctgcaa
aaccacacattcctgcacacagtgtactgccaggatgggagtcccagtgtgggactctct
gaggcctacgacgaggaccagcttttcttcttcgacttttcccagaacactcgggtgcct
cgcctgcccgaatttgctgactgggctcaggaacagggagatgctcctgccattttattt
gacaaagagttctgcgagtggatgatccagcaaatagggccaaaacttgatgggaaaatc
ccggtgtccagagggtttcctatcgctgaagtgttcacgctgaagcccctggagtttggc
aagcccaacactttggtctgttttgtcagtaatctcttcccacccatgctgacagtgaac
tggcagcatcattccgtccctgtggaaggatttgggcctacttttgtctcagctgtcgat
ggactcagcttccaggccttttcttacttaaacttcacaccagaaccttctgacattttc
tcctgcattgtgactcacgaaattgaccgctacacagcaattgcctattgggtaccccgg
aacgcactgccctcagatctgctggagaatgtgctgtgtggcgtggcctttggcctgggt
gtgctgggcatcatcgtgggcattgttctcatcatctacttccggaagccttgctcaggt
gactga

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