KEGG   Homo sapiens (human): 3122Help
Entry
3122              CDS       T01001                                 

Gene name
HLA-DRA, HLA-DRA1, MLRW
Definition
major histocompatibility complex, class II, DR alpha
Orthology
K06752  
major histocompatibility complex, class II
Organism
hsa  Homo sapiens (human)
Pathway
Phagosome
Cell adhesion molecules (CAMs)
Antigen processing and presentation
Hematopoietic cell lineage
Intestinal immune network for IgA production
Type I diabetes mellitus
Leishmaniasis
Toxoplasmosis
Staphylococcus aureus infection
Tuberculosis
Influenza A
HTLV-I infection
Herpes simplex infection
Epstein-Barr virus infection
Asthma
Autoimmune thyroid disease
Inflammatory bowel disease (IBD)
Systemic lupus erythematosus
Rheumatoid arthritis
Allograft rejection
Graft-versus-host disease
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    3122 (HLA-DRA)
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    3122 (HLA-DRA)
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    3122 (HLA-DRA)
   04612 Antigen processing and presentation
    3122 (HLA-DRA)
   04672 Intestinal immune network for IgA production
    3122 (HLA-DRA)
 Human Diseases
  Immune diseases
   05310 Asthma
    3122 (HLA-DRA)
   05322 Systemic lupus erythematosus
    3122 (HLA-DRA)
   05323 Rheumatoid arthritis
    3122 (HLA-DRA)
   05320 Autoimmune thyroid disease
    3122 (HLA-DRA)
   05321 Inflammatiory bowel disease (IBD)
    3122 (HLA-DRA)
   05330 Allograft rejection
    3122 (HLA-DRA)
   05332 Graft-versus-host disease
    3122 (HLA-DRA)
  Cardiovascular diseases
   05416 Viral myocarditis
    3122 (HLA-DRA)
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    3122 (HLA-DRA)
  Infectious diseases
   05150 Staphylococcus aureus infection
    3122 (HLA-DRA)
   05152 Tuberculosis
    3122 (HLA-DRA)
   05166 HTLV-I infection
    3122 (HLA-DRA)
   05164 Influenza A
    3122 (HLA-DRA)
   05168 Herpes simplex infection
    3122 (HLA-DRA)
   05169 Epstein-Barr virus infection
    3122 (HLA-DRA)
   05145 Toxoplasmosis
    3122 (HLA-DRA)
   05140 Leishmaniasis
    3122 (HLA-DRA)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   3122 (HLA-DRA)
  Exosomal proteins of epithelial cells
   3122 (HLA-DRA)
  Exosomal proteins of breast milk
   3122 (HLA-DRA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
6p21.3
AA seq 254 aa AA seqDB search
MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVD
MAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNS
PVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLP
STEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIK
GLRKSNAAERRGPL
NT seq 765 nt NT seq  +upstreamnt  +downstreamnt
atggccataagtggagtccctgtgctaggatttttcatcatagctgtgctgatgagcgct
caggaatcatgggctatcaaagaagaacatgtgatcatccaggccgagttctatctgaat
cctgaccaatcaggcgagtttatgtttgactttgatggtgatgagattttccatgtggat
atggcaaagaaggagacggtctggcggcttgaagaatttggacgatttgccagctttgag
gctcaaggtgcattggccaacatagctgtggacaaagccaacctggaaatcatgacaaag
cgctccaactatactccgatcaccaatgtacctccagaggtaactgtgctcacaaacagc
cctgtggaactgagagagcccaacgtcctcatctgtttcatagacaagttcaccccacca
gtggtcaatgtcacgtggcttcgaaatggaaaacctgtcaccacaggagtgtcagagaca
gtcttcctgcccagggaagaccaccttttccgcaagttccactatctccccttcctgccc
tcaactgaggacgtttacgactgcagggtggagcactggggcttggatgagcctcttctc
aagcactgggagtttgatgctccaagccctctcccagagactacagagaacgtggtgtgt
gccctgggcctgactgtgggtctggtgggcatcattattgggaccatcttcatcatcaag
ggattgcgcaaaagcaatgcagcagaacgcagggggcctctgtaa

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