KEGG   Homo sapiens (human): 3133Help
Entry
3133              CDS       T01001                                 

Gene name
HLA-E, EA1.2, EA2.1, HLA-6.2, MHC, QA1
Definition
major histocompatibility complex, class I, E
Orthology
K06751  
major histocompatibility complex, class I
Organism
hsa  Homo sapiens (human)
Pathway
Endocytosis
Phagosome
Cell adhesion molecules (CAMs)
Antigen processing and presentation
Natural killer cell mediated cytotoxicity
Type I diabetes mellitus
HTLV-I infection
Herpes simplex infection
Epstein-Barr virus infection
Viral carcinogenesis
Autoimmune thyroid disease
Allograft rejection
Graft-versus-host disease
Viral myocarditis
Disease
H00344  
Leprosy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    3133 (HLA-E)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    3133 (HLA-E)
   04145 Phagosome
    3133 (HLA-E)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    3133 (HLA-E)
   04612 Antigen processing and presentation
    3133 (HLA-E)
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    3133 (HLA-E)
  Immune diseases
   05320 Autoimmune thyroid disease
    3133 (HLA-E)
   05330 Allograft rejection
    3133 (HLA-E)
   05332 Graft-versus-host disease
    3133 (HLA-E)
  Cardiovascular diseases
   05416 Viral myocarditis
    3133 (HLA-E)
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    3133 (HLA-E)
  Infectious diseases
   05166 HTLV-I infection
    3133 (HLA-E)
   05168 Herpes simplex infection
    3133 (HLA-E)
   05169 Epstein-Barr virus infection
    3133 (HLA-E)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   3133 (HLA-E)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
6p21.3
AA seq 358 aa AA seqDB search
MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND
AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH
GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY
LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ
DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ
PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSESHSL
NT seq 1077 nt NT seq  +upstreamnt  +downstreamnt
atggtagatggaaccctccttttactcctctcggaggccctggcccttacccagacctgg
gcgggctcccactccttgaagtatttccacacttccgtgtcccggcccggccgcggggag
ccccgcttcatctctgtgggctacgtggacgacacccagttcgtgcgcttcgacaacgac
gccgcgagtccgaggatggtgccgcgggcgccgtggatggagcaggaggggtcagagtat
tgggaccgggagacacggagcgccagggacaccgcacagattttccgagtgaatctgcgg
acgctgcgcggctactacaatcagagcgaggccgggtctcacaccctgcagtggatgcat
ggctgcgagctggggcccgacgggcgcttcctccgcgggtatgaacagttcgcctacgac
ggcaaggattatctcaccctgaatgaggacctgcgctcctggaccgcggtggacacggcg
gctcagatctccgagcaaaagtcaaatgatgcctctgaggcggagcaccagagagcctac
ctggaagacacatgcgtggagtggctccacaaatacctggagaaggggaaggagacgctg
cttcacctggagcccccaaagacacacgtgactcaccaccccatctctgaccatgaggcc
accctgaggtgctgggccctgggcttctaccctgcggagatcacactgacctggcagcag
gatggggagggccatacccaggacacggagctcgtggagaccaggcctgcaggggatgga
accttccagaagtgggcagctgtggtggtgccttctggagaggagcagagatacacgtgc
catgtgcagcatgaggggctacccgagcccgtcaccctgagatggaagccggcttcccag
cccaccatccccatcgtgggcatcattgctggcctggttctccttggatctgtggtctct
ggagctgtggttgctgctgtgatatggaggaagaagagctcaggtggaaaaggagggagc
tactctaaggctgagtggagcgacagtgcccaggggtctgagtctcacagcttgtaa

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