KEGG   Homo sapiens (human): 3265Help
Entry
3265              CDS       T01001                                 

Gene name
HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
Definition
Harvey rat sarcoma viral oncogene homolog
Orthology
K02833  
GTPase HRas
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Axon guidance
VEGF signaling pathway
Focal adhesion
Tight junction
Gap junction
Signaling pathways regulating pluripotency of stem cells
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Long-term potentiation
Neurotrophin signaling pathway
Cholinergic synapse
Serotonergic synapse
Long-term depression
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Alcoholism
Hepatitis C
Hepatitis B
HTLV-I infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Thyroid cancer
Melanoma
Bladder cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Central carbon metabolism in cancer
Choline metabolism in cancer
Disease
H00022  
Bladder cancer
H00025  
Penile cancer
H00030  
Cervical cancer
H00032  
Thyroid cancer
H00040  
Squamous cell carcinoma
H00048  
Hepatocellular carcinoma
H00523  
Noonan syndrome and related disorders
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    3265 (HRAS)
   04015 Rap1 signaling pathway
    3265 (HRAS)
   04010 MAPK signaling pathway
    3265 (HRAS)
   04012 ErbB signaling pathway
    3265 (HRAS)
   04370 VEGF signaling pathway
    3265 (HRAS)
   04068 FoxO signaling pathway
    3265 (HRAS)
   04151 PI3K-Akt signaling pathway
    3265 (HRAS)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    3265 (HRAS)
  Cell motility
   04810 Regulation of actin cytoskeleton
    3265 (HRAS)
  Cellular commiunity
   04510 Focal adhesion
    3265 (HRAS)
   04530 Tight junction
    3265 (HRAS)
   04540 Gap junction
    3265 (HRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    3265 (HRAS)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    3265 (HRAS)
   04660 T cell receptor signaling pathway
    3265 (HRAS)
   04662 B cell receptor signaling pathway
    3265 (HRAS)
   04664 Fc epsilon RI signaling pathway
    3265 (HRAS)
   04062 Chemokine signaling pathway
    3265 (HRAS)
  Endocrine system
   04910 Insulin signaling pathway
    3265 (HRAS)
   04912 GnRH signaling pathway
    3265 (HRAS)
   04915 Estrogen signaling pathway
    3265 (HRAS)
   04917 Prolactin signaling pathway
    3265 (HRAS)
   04921 Oxytocin signaling pathway
    3265 (HRAS)
   04919 Thyroid hormone signaling pathway
    3265 (HRAS)
   04916 Melanogenesis
    3265 (HRAS)
  Nervous system
   04725 Cholinergic synapse
    3265 (HRAS)
   04726 Serotonergic synapse
    3265 (HRAS)
   04720 Long-term potentiation
    3265 (HRAS)
   04730 Long-term depression
    3265 (HRAS)
   04722 Neurotrophin signaling pathway
    3265 (HRAS)
  Development
   04360 Axon guidance
    3265 (HRAS)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    3265 (HRAS)
   05230 Central carbon metabolism in cancer
    3265 (HRAS)
   05231 Choline metabolism in cancer
    3265 (HRAS)
   05206 MicroRNAs in cancer
    3265 (HRAS)
   05205 Proteoglycans in cancer
    3265 (HRAS)
   05203 Viral carcinogenesis
    3265 (HRAS)
   05214 Glioma
    3265 (HRAS)
   05216 Thyroid cancer
    3265 (HRAS)
   05221 Acute myeloid leukemia
    3265 (HRAS)
   05220 Chronic myeloid leukemia
    3265 (HRAS)
   05218 Melanoma
    3265 (HRAS)
   05211 Renal cell carcinoma
    3265 (HRAS)
   05219 Bladder cancer
    3265 (HRAS)
   05215 Prostate cancer
    3265 (HRAS)
   05213 Endometrial cancer
    3265 (HRAS)
   05223 Non-small cell lung cancer
    3265 (HRAS)
  Substance dependence
   05034 Alcoholism
    3265 (HRAS)
  Infectious diseases
   05166 HTLV-I infection
    3265 (HRAS)
   05161 Hepatitis B
    3265 (HRAS)
   05160 Hepatitis C
    3265 (HRAS)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   3265 (HRAS)
  Exosomal proteins of colorectal cancer cells
   3265 (HRAS)
GTP-binding proteins [BR:hsa04031]
 Small (Monomeric) G-proteins
  Ras Family
   Ras [OT]
    3265 (HRAS)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
11p15.5
AA seq 189 aa AA seqDB search
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG
CMSCKCVLS
NT seq 570 nt NT seq  +upstreamnt  +downstreamnt
atgacggaatataagctggtggtggtgggcgccggcggtgtgggcaagagtgcgctgacc
atccagctgatccagaaccattttgtggacgaatacgaccccactatagaggattcctac
cggaagcaggtggtcattgatggggagacgtgcctgttggacatcctggataccgccggc
caggaggagtacagcgccatgcgggaccagtacatgcgcaccggggagggcttcctgtgt
gtgtttgccatcaacaacaccaagtcttttgaggacatccaccagtacagggagcagatc
aaacgggtgaaggactcggatgacgtgcccatggtgctggtggggaacaagtgtgacctg
gctgcacgcactgtggaatctcggcaggctcaggacctcgcccgaagctacggcatcccc
tacatcgagacctcggccaagacccggcagggagtggaggatgccttctacacgttggtg
cgtgagatccggcagcacaagctgcggaagctgaaccctcctgatgagagtggccccggc
tgcatgagctgcaagtgtgtgctctcctga

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