KEGG   Homo sapiens (human): 3320Help
Entry
3320              CDS       T01001                                 

Gene name
HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2
Definition
heat shock protein 90kDa alpha (cytosolic), class A member 1
Orthology
K04079  
molecular chaperone HtpG
Organism
hsa  Homo sapiens (human)
Pathway
Protein processing in endoplasmic reticulum
PI3K-Akt signaling pathway
Antigen processing and presentation
NOD-like receptor signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Pathways in cancer
Prostate cancer
Drug target
Class
Genetic Information Processing; Folding, sorting and degradation; Protein processing in endoplasmic reticulum [PATH:hsa04141]
Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:hsa04151]
Organismal Systems; Immune system; NOD-like receptor signaling pathway [PATH:hsa04621]
Organismal Systems; Immune system; Antigen processing and presentation [PATH:hsa04612]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:hsa04915]
Organismal Systems; Endocrine system; Progesterone-mediated oocyte maturation [PATH:hsa04914]
Human Diseases; Cancers; Pathways in cancer [PATH:hsa05200]
Human Diseases; Cancers; Prostate cancer [PATH:hsa05215]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 
3T0H 3T10 3WHA 2YK9 3B28 3VHA 2YI7 3VHC 2YKE 2YKJ 3O0I 3T2S 3T1K 3B27 1BYQ 3VHD 2YEF 3EKO 3RKZ 3QTF 3R91 3R92 3HHU 4AWQ 4EGH 4EEH 2YI0 3BMY 3BM9 2YJW 3OWD 4NH8 4HY6 1YER 2XJX 2YKI 2YKC 2QFO 4EGK 4B7P 4AWO 4FCR 3B24 3RLP 3RLR 3R4M 3R4P 1YC1 4JQL 2YE5 2YEA 2YK2 2XDU 3D0B 3B25 3INX 1OSF 4EGI 3QDD 2CCS 3TUH 2YI6 3OW6 2QG2 1YC4 4AWP 2YJX 2QG0 4BQG 3RLQ 2YE2 2XJJ 3MNR 2XAB 3HYY 3HZ5 2WI3 3FT5 1YET 2YKB 2YE3 2XK2 3K97 3INW 3HEK 2JJC 2XDS 2XDK 2XDL 1UY8 4NH7 4BQJ 4FCP 4EFU 3R4N 3FT8 3EKR 2VCI 2H55 3OWB 2BSM 2WI2 3B26 2YEC 2YED 2YEH 3K99 2WI5 2FWY 2FWZ 4EFT 1YC3 4FCQ 2WI6 3T0Z 2YE7 2YE9 2YEI 2YEJ 2XHR 1YES 2XJG 2XHT 2YE4 2YE8 2YEE 3HYZ 3HZ1 2WI1 2YEB 3K98 2WI4 2XDX 2YI5 2YEG 2WI7 2VCJ 2YE6 3R4O 2XHX 3Q6M 3Q6N 2QF6 2K5B 2UWD 2CCT 2CCU 2BZ5 2BYH 2BYI 2BT0 1UY6 1UY7 1UY9 1UYC 1UYD 1UYE 1UYF 1UYG 1UYH 1UYI 1UYK 1UYL
Thumbnails

Jmol
Position
14q32.33
AA seq 854 aa AA seqDB search
MPPCSGGDGSTPPGPSLRDRDCPAQSAEYPRDRLDPRPGSPSEASSPPFLRSRAPVNWYQ
EKAQVFLWHLMVSGSTTLLCLWKQPFHVSAFPVTASLAFRQSQGAGQHLYKDLQPFILLR
LLMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDK
IRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAF
MEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGE
PMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEK
EDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWT
RNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKK
NNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVK
KCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLK
DYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEG
KTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCC
IVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKS
VKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPP
LEGDDDTSRMEEVD
NT seq 2565 nt NT seq  +upstreamnt  +downstreamnt
atgcccccgtgttcgggcggggacggctccacccctcctgggccctcccttcgggacagg
gactgtcccgcccagagtgctgaatacccgcgcgaccgtctggatccccgcccaggaagc
ccctctgaagcctcctcgccgccgtttctgagaagcagggcacctgttaactggtaccaa
gaaaaggcccaagtgtttctctggcatctgatggtgtctggatccaccactctactctgt
ctctggaaacagcccttccacgtctctgcattccctgtcaccgcgtcactggccttcaga
cagagccaaggtgcagggcaacacctctacaaggatctgcagccatttatattgcttagg
ctactgatgcctgaggaaacccagacccaagaccaaccgatggaggaggaggaggttgag
acgttcgcctttcaggcagaaattgcccagttgatgtcattgatcatcaatactttctac
tcgaacaaagagatctttctgagagagctcatttcaaattcatcagatgcattggacaaa
atccggtatgaaagcttgacagatcccagtaaattagactctgggaaagagctgcatatt
aaccttataccgaacaaacaagatcgaactctcactattgtggatactggaattggaatg
accaaggctgacttgatcaataaccttggtactatcgccaagtctgggaccaaagcgttc
atggaagctttgcaggctggtgcagatatctctatgattggccagttcggtgttggtttt
tattctgcttatttggttgctgagaaagtaactgtgatcaccaaacataacgatgatgag
cagtacgcttgggagtcctcagcagggggatcattcacagtgaggacagacacaggtgaa
cctatgggtcgtggaacaaaagttatcctacacctgaaagaagaccaaactgagtacttg
gaggaacgaagaataaaggagattgtgaagaaacattctcagtttattggatatcccatt
actctttttgtggagaaggaacgtgataaagaagtaagcgatgatgaggctgaagaaaag
gaagacaaagaagaagaaaaagaaaaagaagagaaagagtcggaagacaaacctgaaatt
gaagatgttggttctgatgaggaagaagaaaagaaggatggtgacaagaagaagaagaag
aagattaaggaaaagtacatcgatcaagaagagctcaacaaaacaaagcccatctggacc
agaaatcccgacgatattactaatgaggagtacggagaattctataagagcttgaccaat
gactgggaagatcacttggcagtgaagcatttttcagttgaaggacagttggaattcaga
gcccttctatttgtcccacgacgtgctccttttgatctgtttgaaaacagaaagaaaaag
aacaacatcaaattgtatgtacgcagagttttcatcatggataactgtgaggagctaatc
cctgaatatctgaacttcattagaggggtggtagactcggaggatctccctctaaacata
tcccgtgagatgttgcaacaaagcaaaattttgaaagttatcaggaagaatttggtcaaa
aaatgcttagaactctttactgaactggcggaagataaagagaactacaagaaattctat
gagcagttctctaaaaacataaagcttggaatacacgaagactctcaaaatcggaagaag
ctttcagagctgttaaggtactacacatctgcctctggtgatgagatggtttctctcaag
gactactgcaccagaatgaaggagaaccagaaacatatctattatatcacaggtgagacc
aaggaccaggtagctaactcagcctttgtggaacgtcttcggaaacatggcttagaagtg
atctatatgattgagcccattgatgagtactgtgtccaacagctgaaggaatttgagggg
aagactttagtgtcagtcaccaaagaaggcctggaacttccagaggatgaagaagagaaa
aagaagcaggaagagaaaaaaacaaagtttgagaacctctgcaaaatcatgaaagacata
ttggagaaaaaagttgaaaaggtggttgtgtcaaaccgattggtgacatctccatgctgt
attgtcacaagcacatatggctggacagcaaacatggagagaatcatgaaagctcaagcc
ctaagagacaactcaacaatgggttacatggcagcaaagaaacacctggagataaaccct
gaccattccattattgagaccttaaggcaaaaggcagaggctgataagaacgacaagtct
gtgaaggatctggtcatcttgctttatgaaactgcgctcctgtcttctggcttcagtctg
gaagatccccagacacatgctaacaggatctacaggatgatcaaacttggtctgggtatt
gatgaagatgaccctactgctgatgataccagtgctgctgtaactgaagaaatgccaccc
cttgaaggagatgacgacacatcacgcatggaagaagtagactaa

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