KEGG   Homo sapiens (human): 347733Help
Entry
347733            CDS       T01001                                 

Gene name
TUBB2B, CDCBM7, PMGYSA, bA506K6.1
Definition
(RefSeq) tubulin beta 2B class IIb
  KO
K07375  tubulin beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04540  Gap junction
hsa05130  Pathogenic Escherichia coli infection
Disease
H00271  Polymicrogyria
Drug target
Batabulin (DG01412): D03059 D06560
Brentuximab vedotin: D09587
Cabazitaxel (DG00695): D09755 D10452
Colchicine: D00570
Docetaxel (DG00694): D02165 D07866
Eribulin: D08914
Estramustine (DG00724): D02398 D04066 D06397
Glembatumumab vedotin: D09912
Indibulin: D10013
Ixabepilone: D04645
Lexibulin: D10073
Maytansine: D04864
Paclitaxel: D00491
Paclitaxel poliglumex: D05333
Podophyllotoxin: D05529
Soblidotin: D01919
Taltobulin: D06001
Trastuzumab emtansine: D09980
Verubulin (DG01411): D10029 D10030
Vinblastine (DG00689): D01068 D08675
Vincristine (DG00690): D02197 D08679
Vindesine (DG00691): D01769 D06304
Vinepidine sulfate: D06305
Vinflunine: D09032
Vinglycinate sulfate: D06306
Vinleurosine sulfate: D06307
Vinorelbine (DG00692): D01935 D08680
Vinrosidine sulfate: D06308
Vinzolidine sulfate: D06309
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    347733 (TUBB2B)
  Cellular community - eukaryotes
   04540 Gap junction
    347733 (TUBB2B)
 Human Diseases
  Infectious diseases
   05130 Pathogenic Escherichia coli infection
    347733 (TUBB2B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Microtubules and associated factors
    Other tubulins
     347733 (TUBB2B)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    347733 (TUBB2B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   347733 (TUBB2B)
  Exosomal proteins of colorectal cancer cells
   347733 (TUBB2B)
  Exosomal proteins of bladder cancer cells
   347733 (TUBB2B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Tubulin Tubulin_C Misat_Tub_SegII Tubulin_3 Tubulin_2
Motif
Other DBs
NCBI-GeneID: 347733
NCBI-ProteinID: NP_821080
OMIM: 612850
HGNC: 30829
Ensembl: ENSG00000137285
Vega: OTTHUMG00000014143
Pharos: Q9BVA1(Tclin)
UniProt: Q9BVA1
Position
6p25.2
AA seq 445 aa AA seqDB search
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV
PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
EYQQYQDATADEQGEFEEEEGEDEA
NT seq 1338 nt NT seq  +upstreamnt  +downstreamnt
atgcgtgagatcgtgcacatccaggcgggccagtgcggcaaccagatcggcgccaagttt
tgggaggtcatcagtgatgagcatgggattgaccccactggcagttaccatggagacagt
gatttgcagctggagagaatcaatgtttactacaatgaagccactggtaacaaatatgtt
cctcgggccatcctcgtggatctggagccaggcacgatggattcggttaggtctggacca
ttcggccagatcttcagaccagacaatttcgtgtttggccagagtggagccgggaataac
tgggccaagggccactacacagagggagccgagctggtcgactcggtcctggatgtggtg
aggaaggagtcagagagctgtgactgtctccagggcttccagctgacccactctctgggg
ggcggcacggggtccgggatgggcaccctgctcatcagcaagatccgggaagagtaccca
gaccgcatcatgaacaccttcagcgtcatgccctcacccaaggtgtcagacacggtggtg
gagccctacaacgccaccctctcggtccaccagctggtggaaaacacagatgaaacctac
tgcattgacaacgaggccctgtatgacatctgcttccgcaccctgaagctgaccaccccc
acctacggggacctcaaccacctggtgtcggccaccatgagcggggtcaccacctgcctg
cgcttcccgggccagctgaacgcagacctgcgcaagctggcggtgaacatggtgcccttc
cctcgcctgcacttcttcatgcccggcttcgcgcccctgaccagccggggcagccagcag
taccgggcgctcacggtgcccgagctcacccagcagatgttcgactccaagaacatgatg
gccgcctgcgacccgcgccacggccgctacctgacggtggctgccatcttccggggccgc
atgtccatgaaggaggtggacgagcagatgctcaacgtgcagaacaagaacagcagctac
ttcgtggagtggatccccaacaacgtgaagacggccgtgtgcgacatcccgccccgcggc
ctgaagatgtcggccaccttcatcggcaacagcacggccatccaggagctgttcaagcgc
atctccgagcagttcacggccatgttccggcgcaaggccttcctgcactggtacacgggc
gagggcatggacgagatggagttcaccgaggccgagagcaacatgaacgacctggtgtcc
gagtaccagcagtaccaggacgccacggccgacgaacaaggggagttcgaggaggaggag
ggcgaggacgaggcgtag

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