KEGG   Homo sapiens (human): 353497
Entry
353497            CDS       T01001                                 
Symbol
POLN, POL4P
Name
(RefSeq) DNA polymerase nu
  KO
K16618  DNA polymerase nu [EC:2.7.7.7]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03460  Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03460 Fanconi anemia pathway
    353497 (POLN)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    353497 (POLN)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     353497 (POLN)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  TLS (translesion DNA synthesis) factors
   A-family DNA polymerase
    353497 (POLN)
SSDB
Motif
Pfam: DNA_pol_A DNA_pol_P_Exo
Other DBs
NCBI-GeneID: 353497
NCBI-ProteinID: NP_861524
OMIM: 610887
HGNC: 18870
Ensembl: ENSG00000130997
UniProt: Q7Z5Q5
Structure
Position
4:complement(2071918..2242121)
AA seq 900 aa
MENYEALVGFDLCNTPLSSVAQKIMSAMHSGDLVDSKTWGKSTETMEVINKSSVKYSVQL
EDRKTQSPEKKDLKSLRSQTSRGSAKLSPQSFSVRLTDQLSADQKQKSISSLTLSSCLIP
QYNQEASVLQKKGHKRKHFLMENINNENKGSINLKRKHITYNNLSEKTSKQMALEEDTDD
AEGYLNSGNSGALKKHFCDIRHLDDWAKSQLIEMLKQAAALVITVMYTDGSTQLGADQTP
VSSVRGIVVLVKRQAEGGHGCPDAPACGPVLEGFVSDDPCIYIQIEHSAIWDQEQEAHQQ
FARNVLFQTMKCKCPVICFNAKDFVRIVLQFFGNDGSWKHVADFIGLDPRIAAWLIDPSD
ATPSFEDLVEKYCEKSITVKVNSTYGNSSRNIVNQNVRENLKTLYRLTMDLCSKLKDYGL
WQLFRTLELPLIPILAVMESHAIQVNKEEMEKTSALLGARLKELEQEAHFVAGERFLITS
NNQLREILFGKLKLHLLSQRNSLPRTGLQKYPSTSEAVLNALRDLHPLPKIILEYRQVHK
IKSTFVDGLLACMKKGSISSTWNQTGTVTGRLSAKHPNIQGISKHPIQITTPKNFKGKED
KILTISPRAMFVSSKGHTFLAADFSQIELRILTHLSGDPELLKLFQESERDDVFSTLTSQ
WKDVPVEQVTHADREQTKKVVYAVVYGAGKERLAACLGVPIQEAAQFLESFLQKYKKIKD
FARAAIAQCHQTGCVVSIMGRRRPLPRIHAHDQQLRAQAERQAVNFVVQGSAADLCKLAM
IHVFTAVAASHTLTARLVAQIHDELLFEVEDPQIPECAALVRRTMESLEQVQALELQLQV
PLKVSLSAGRSWGHLVPLQEAWGPPPGPCRTESPSNSLAAPGSPASTQPPPLHFSPSFCL
NT seq 2703 nt   +upstreamnt  +downstreamnt
atggaaaattatgaggcattggtaggctttgatctctgtaatacaccgctctccagtgtt
gctcagaagattatgtctgctatgcattcaggtgatttagtggattctaagacttgggga
aagagtacagagactatggaagtgataaacaagtccagtgttaagtattcagtacaactt
gaagacaggaagactcaatcaccagaaaaaaaggatcttaaatctttaagaagtcagaca
tcaagaggttctgccaagctgtctcctcagtccttcagtgtcaggctcacagatcagctg
tctgctgaccaaaaacagaagagcatcagctcattgactctttcaagttgtttaattcca
cagtataatcaagaggcttcagttctacagaaaaaggggcataaaagaaagcatttccta
atggagaatataaataatgaaaataaaggaagcattaatcttaaaagaaaacatattaca
tataataatttgtcagagaaaacaagtaaacaaatggcattggaagaagatactgatgac
gccgaaggctacctaaattctgggaactcaggagcattgaaaaaacatttttgtgatatt
aggcatttggatgattgggcaaaaagccagctgattgaaatgctcaaacaggcagcagcc
ctggtgataactgtgatgtatactgatggttccacccagctaggagctgaccagaccccc
gtttcttctgttagaggaattgtggtgttagtaaaacgccaagcagagggtggccatggc
tgtccagatgccccggcctgtggtcctgttctggagggctttgtgtcagatgatccatgc
atctacattcaaatagagcactctgctatctgggaccaagaacaggaggcacatcaacaa
tttgcccggaacgtgctatttcaaacaatgaaatgtaaatgtcctgttatttgttttaat
gctaaggattttgtgagaatagtgctgcagttttttggcaatgatggcagttggaagcat
gttgctgattttatagggctagatcccagaattgctgcatggcttatagatcctagtgat
gccacaccctcttttgaagatttagtagaaaaatactgtgaaaaatccattacagttaaa
gtgaacagcacatatggaaattcctcaagaaatattgtgaatcagaatgtacgtgagaac
ctgaagacactctacagacttacaatggacctttgctctaaactgaaggattatggttta
tggcaactatttcgtactttggagcttcctctgataccaattttggcagtgatggaaagc
catgccattcaggtgaacaaagaggagatggagaagacgtcagcacttcttggggctcgt
ctcaaggaattggagcaagaagctcattttgttgcaggagaacggtttcttataacgagc
aataaccagcttcgagagatcctctttggcaagttaaagctgcacctgctgagtcaaagg
aacagtctccccagaacggggttgcagaaatacccgtctacatcagaagcagtgttaaat
gctctgcgagaccttcatccattacccaagataattttggaatacaggcaggttcacaag
atcaagtcaacctttgtagatggattactagcttgcatgaaaaagggctccatttcctct
acatggaatcagactggaactgtgactggaagactttcagccaagcatcctaatatccaa
ggtatctccaagcacccaattcagattactacacctaagaattttaaaggtaaagaagac
aagattctcacgatctccccgagggccatgtttgtttcatccaaaggccacacctttcta
gcagcagacttttcacagattgaattgcgcattcttacacatttatctggagatccggaa
cttctgaagttattccaggaatctgaaagagatgatgtattttctactctgacttcacag
tggaaggatgtgcccgtggaacaggtgacacacgcagacagagagcaaaccaagaaggtg
gtgtacgcggtggtctatggagcagggaaggagcggctggctgcttgccttggagttcct
attcaggaagctgcccagtttttggagagttttttgcagaagtacaagaaaatcaaggac
ttcgcccgagcagctattgcccagtgtcaccagacaggctgtgtggtgtccatcatgggc
agaaggagacccctgccaaggattcacgctcatgaccagcaactccgggcacaagcagag
cgacaggcagtgaacttcgtggtgcaaggctccgctgctgacctctgcaagctggccatg
atccatgtcttcactgcagtggctgcttcccacaccttgacggccaggctggtggcccag
atccatgatgagctgctgtttgaagtggaagatccgcagatcccggagtgtgcagctctc
gtcaggaggaccatggagtccttggaacaggtgcaggcattggagctgcagcttcaggta
cccctcaaggtgagcctgagtgccggccgctcatggggacacctggtgccactgcaggag
gcctggggccctccgccaggcccatgtcgcactgagtctcccagcaacagcctggctgcc
cctgggtcccctgccagcacccagcccccacccctgcatttttcgccttcattttgtctg
tag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
3D Structure (4)   
   PDB (4)   
Protein domain (2)   
   Pfam (2)   
All databases (48)   

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