KEGG T01001: 3620

Homo sapiens (human): 3620

Entry

3620 CDS T01001

Gene name

IDO1, IDO, IDO-1, INDO

Definition

indoleamine 2,3-dioxygenase 1 (EC:1.13.11.52)

Orthology

K00463

indoleamine 2,3-dioxygenase [EC:1.13.11.52]

Organism

hsa Homo sapiens (human)

Pathway

hsa00380	Tryptophan metabolism
hsa01100	Metabolic pathways
hsa05143	African trypanosomiasis

Class

Metabolism; Amino acid metabolism; Tryptophan metabolism [PATH:hsa00380]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:hsa05143]

SSDB

Motif

Pfam:

IDO DUF1864 Meckelin Erf4

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

UniProt:

Structure

PDB:

2D0T 2D0U

Position

8p12-p11

AA seq 403 aa
MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE
KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLEL
PPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKV
IPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGN
PQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMP
PAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ
QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG

NT seq 1212 nt +upstreamnt +downstreamnt
atggcacacgctatggaaaactcctggacaatcagtaaagagtaccatattgatgaagaa
gtgggctttgctctgccaaatccacaggaaaatctacctgatttttataatgactggatg
ttcattgctaaacatctgcctgatctcatagagtctggccagcttcgagaaagagttgag
aagttaaacatgctcagcattgatcatctcacagaccacaagtcacagcgccttgcacgt
ctagttctgggatgcatcaccatggcatatgtgtggggcaaaggtcatggagatgtccgt
aaggtcttgccaagaaatattgctgttccttactgccaactctccaagaaactggaactg
cctcctattttggtttatgcagactgtgtcttggcaaactggaagaaaaaggatcctaat
aagcccctgacttatgagaacatggacgttttgttctcatttcgtgatggagactgcagt
aaaggattcttcctggtctctctattggtggaaatagcagctgcttctgcaatcaaagta
attcctactgtattcaaggcaatgcaaatgcaagaacgggacactttgctaaaggcgctg
ttggaaatagcttcttgcttggagaaagcccttcaagtgtttcaccaaatccacgatcat
gtgaacccaaaagcatttttcagtgttcttcgcatatatttgtctggctggaaaggcaac
ccccagctatcagacggtctggtgtatgaagggttctgggaagacccaaaggagtttgca
gggggcagtgcaggccaaagcagcgtctttcagtgctttgacgtcctgctgggcatccag
cagactgctggtggaggacatgctgctcagttcctccaggacatgagaagatatatgcca
ccagctcacaggaacttcctgtgctcattagagtcaaatccctcagtccgtgagtttgtc
ctttcaaaaggtgatgctggcctgcgggaagcttatgacgcctgtgtgaaagctctggtc
tccctgaggagctaccatctgcaaatcgtgactaagtacatcctgattcctgcaagccag
cagccaaaggagaataagacctctgaagacccttcaaaactggaagccaaaggaactgga
ggcactgatttaatgaatttcctgaagactgtaagaagtacaactgagaaatcccttttg
aaggaaggttaa

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (23)   
   RefSeq(nuc) (1)   
   GenBank (11)   
   EMBL (11)   
3D Structure (2)   
   PDB (2)   
Protein domain (4)   
   Pfam (4)   
All databases (64)   

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