KEGG   Homo sapiens (human): 3620Help
Entry
3620              CDS       T01001                                 

Gene name
IDO1, IDO, IDO-1, INDO
Definition
indoleamine 2,3-dioxygenase 1 (EC:1.13.11.52)
Orthology
K00463  
indoleamine 2,3-dioxygenase [EC:1.13.11.52]
Organism
hsa  Homo sapiens (human)
Pathway
Tryptophan metabolism
Metabolic pathways
African trypanosomiasis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Amino acid metabolism
   00380 Tryptophan metabolism
    3620 (IDO1)
 Human Diseases
  Infectious diseases
   05143 African trypanosomiasis
    3620 (IDO1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.52  indoleamine 2,3-dioxygenase
     3620 (IDO1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
UniProt: 
Structure
PDB: 

Jmol
Position
8p12-p11
AA seq 403 aa AA seqDB search
MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE
KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLEL
PPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKV
IPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGN
PQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMP
PAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ
QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
NT seq 1212 nt NT seq  +upstreamnt  +downstreamnt
atggcacacgctatggaaaactcctggacaatcagtaaagagtaccatattgatgaagaa
gtgggctttgctctgccaaatccacaggaaaatctacctgatttttataatgactggatg
ttcattgctaaacatctgcctgatctcatagagtctggccagcttcgagaaagagttgag
aagttaaacatgctcagcattgatcatctcacagaccacaagtcacagcgccttgcacgt
ctagttctgggatgcatcaccatggcatatgtgtggggcaaaggtcatggagatgtccgt
aaggtcttgccaagaaatattgctgttccttactgccaactctccaagaaactggaactg
cctcctattttggtttatgcagactgtgtcttggcaaactggaagaaaaaggatcctaat
aagcccctgacttatgagaacatggacgttttgttctcatttcgtgatggagactgcagt
aaaggattcttcctggtctctctattggtggaaatagcagctgcttctgcaatcaaagta
attcctactgtattcaaggcaatgcaaatgcaagaacgggacactttgctaaaggcgctg
ttggaaatagcttcttgcttggagaaagcccttcaagtgtttcaccaaatccacgatcat
gtgaacccaaaagcatttttcagtgttcttcgcatatatttgtctggctggaaaggcaac
ccccagctatcagacggtctggtgtatgaagggttctgggaagacccaaaggagtttgca
gggggcagtgcaggccaaagcagcgtctttcagtgctttgacgtcctgctgggcatccag
cagactgctggtggaggacatgctgctcagttcctccaggacatgagaagatatatgcca
ccagctcacaggaacttcctgtgctcattagagtcaaatccctcagtccgtgagtttgtc
ctttcaaaaggtgatgctggcctgcgggaagcttatgacgcctgtgtgaaagctctggtc
tccctgaggagctaccatctgcaaatcgtgactaagtacatcctgattcctgcaagccag
cagccaaaggagaataagacctctgaagacccttcaaaactggaagccaaaggaactgga
ggcactgatttaatgaatttcctgaagactgtaagaagtacaactgagaaatcccttttg
aaggaaggttaa

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