KEGG   Homo sapiens (human): 3661Help
Entry
3661              CDS       T01001                                 

Gene name
IRF3
Definition
interferon regulatory factor 3
Orthology
K05411  
interferon regulatory factor 3
Organism
hsa  Homo sapiens (human)
Pathway
Toll-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Cytosolic DNA-sensing pathway
Pertussis
Hepatitis C
Hepatitis B
Measles
Influenza A
Herpes simplex infection
Epstein-Barr virus infection
Viral carcinogenesis
Class
Organismal Systems; Immune system; Toll-like receptor signaling pathway [PATH:hsa04620]
Organismal Systems; Immune system; RIG-I-like receptor signaling pathway [PATH:hsa04622]
Organismal Systems; Immune system; Cytosolic DNA-sensing pathway [PATH:hsa04623]
Human Diseases; Cancers; Viral carcinogenesis [PATH:hsa05203]
Human Diseases; Infectious diseases; Pertussis [PATH:hsa05133]
Human Diseases; Infectious diseases; Measles [PATH:hsa05162]
Human Diseases; Infectious diseases; Influenza A [PATH:hsa05164]
Human Diseases; Infectious diseases; Hepatitis B [PATH:hsa05161]
Human Diseases; Infectious diseases; Hepatitis C [PATH:hsa05160]
Human Diseases; Infectious diseases; Herpes simplex infection [PATH:hsa05168]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:hsa05169]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
19q13.3-q13.4
AA seq 452 aa AA seqDB search
MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA
TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP
DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT
PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG
WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL
PNSGHGPDGEVPKDKEGGVFDLGPFIVGSWAPRSDYLHGRKRTLTTLCPLVLCGGVMAPG
PAVDQEARDGQGCAHVPQGLGRNGPGRGCLLPGEYCGPAHFQQPPTLPHLRPVQGLPAGL
GGGHGFPGPWGELSPRSSWCASNPPVPHHLNQ
NT seq 1359 nt NT seq  +upstreamnt  +downstreamnt
atgggaaccccaaagccacggatcctgccctggctggtgtcgcagctggacctggggcaa
ctggagggcgtggcctgggtgaacaagagccgcacgcgcttccgcatcccttggaagcac
ggcctacggcaggatgcacagcaggaggatttcggaatcttccaggcctgggccgaggcc
actggtgcatatgttcccgggagggataagccagacctgccaacctggaagaggaatttc
cgctctgccctcaaccgcaaagaagggttgcgtttagcagaggaccggagcaaggaccct
cacgacccacataaaatctacgagtttgtgaactcaggagttggggacttttcccagcca
gacacctctccggacaccaatggtggaggcagtacttctgatacccaggaagacattctg
gatgagttactgggtaacatggtgttggccccactcccagatccgggacccccaagcctg
gctgtagcccctgagccctgccctcagcccctgcggagccccagcttggacaatcccact
cccttcccaaacctggggccctctgagaacccactgaagcggctgttggtgccgggggaa
gagtgggagttcgaggtgacagccttctaccggggccgccaagtcttccagcagaccatc
tcctgcccggagggcctgcggctggtggggtccgaagtgggagacaggacgctgcctgga
tggccagtcacactgccagaccctggcatgtccctgacagacaggggagtgatgagctac
gtgaggcatgtgctgagctgcctgggtgggggactggctctctggcgggccgggcagtgg
ctctgggcccagcggctggggcactgccacacatactgggcagtgagcgaggagctgctc
cccaacagcgggcatgggcctgatggcgaggtccccaaggacaaggaaggaggcgtgttt
gacctggggcccttcattgtaggctcctgggcccccagatctgattaccttcacggaagg
aagcggacgctcaccacgctatgccctctggttctgtgtgggggagtcatggccccagga
ccagccgtggaccaagaggctcgtgatggtcaaggttgtgcccacgtgcctcagggcctt
ggtagaaatggcccgggtagggggtgcctcctccctggagaatactgtggacctgcacat
ttccaacagccacccactctccctcacctccgaccagtacaaggcctacctgcaggactt
ggtggagggcatggatttccagggccctggggagagctgagccctcgctcctcatggtgt
gcctccaacccccctgttccccaccacctcaaccaataa

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