KEGG   Homo sapiens (human): 3685Help
Entry
3685              CDS       T01001                                 

Gene name
ITGAV, CD51, MSK8, VNRA, VTNR
Definition
integrin, alpha V
Orthology
K06487  
integrin alpha V
Organism
hsa  Homo sapiens (human)
Pathway
Phagosome
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Regulation of actin cytoskeleton
Thyroid hormone signaling pathway
Pathways in cancer
Proteoglycans in cancer
Small cell lung cancer
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Drug target
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    3685 (ITGAV)
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    3685 (ITGAV)
   04514 Cell adhesion molecules (CAMs)
    3685 (ITGAV)
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    3685 (ITGAV)
  Cell motility
   04810 Regulation of actin cytoskeleton
    3685 (ITGAV)
  Cell communication
   04510 Focal adhesion
    3685 (ITGAV)
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    3685 (ITGAV)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    3685 (ITGAV)
   05205 Proteoglycans in cancer
    3685 (ITGAV)
   05222 Small cell lung cancer
    3685 (ITGAV)
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    3685 (ITGAV)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    3685 (ITGAV)
   05414 Dilated cardiomyopathy (DCM)
    3685 (ITGAV)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   3685 (ITGAV)
  Exosomal proteins of epithelial cells
   3685 (ITGAV)
Cell adhesion molecules and their ligands [BR:hsa04516]
 1. Immunoglobulin Superfamily
  Neural system
   6/5 subfamily
    L1CAM; L1 cell adhesion molecule [KO:K06550]
     VNR Cell adhesion molecules (CAMs)
      3685 (ITGAV)
   N/0 subfamily
    THY1, CD90; Thy-1 cell surface antigen [KO:K06514]
      3685 (ITGAV)
Cellular antigens [BR:hsa04090]
 Proteins
  3685 (ITGAV)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
2q31-q32
AA seq 1002 aa AA seqDB search
MLLGTLLLILYILMLCRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATG
NRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKT
VEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYD
PNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY
DGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVS
VSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIF
NGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYR
ARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVE
LLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPIT
IFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKK
IYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQT
RQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDL
AVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLH
LQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHL
ITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNH
SYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLL
LLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET
NT seq 3009 nt NT seq  +upstreamnt  +downstreamnt
atgctcctaggcaccctccttctgatcctgtacatcttaatgttgtgccggatgtttctt
ctcgtgggagctcccaaagcaaacaccacccagcctgggattgtggaaggagggcaggtc
ctcaaatgtgactggtcttctacccgccggtgccagccaattgaatttgatgcaacaggc
aatagagattatgccaaggatgatccattggaatttaagtcccatcagtggtttggagca
tctgtgaggtcgaaacaggataaaattttggcctgtgccccattgtaccattggagaact
gagatgaaacaggagcgagagcctgttggaacatgctttcttcaagatggaacaaagact
gttgagtatgctccatgtagatcacaagatattgatgctgatggacagggattttgtcaa
ggaggattcagcattgattttactaaagctgacagagtacttcttggtggtcctggtagc
ttttattggcaaggtcagcttatttcggatcaagtggcagaaatcgtatctaaatacgac
cccaatgtttacagcatcaagtataataaccaattagcaactcggactgcacaagctatt
tttgatgacagctatttgggttattctgtggctgtcggagatttcaatggtgatggcata
gatgactttgtttcaggagttccaagagcagcaaggactttgggaatggtttatatttat
gatgggaagaacatgtcctccttatacaattttactggcgagcagatggctgcatatttc
ggattttctgtagctgccactgacattaatggagatgattatgcagatgtgtttattgga
gcacctctcttcatggatcgtggctctgatggcaaactccaagaggtggggcaggtctca
gtgtctctacagagagcttcaggagacttccagacgacaaagctgaatggatttgaggtc
tttgcacggtttggcagtgccatagctcctttgggagatctggaccaggatggtttcaat
gatattgcaattgctgctccatatgggggtgaagataaaaaaggaattgtttatatcttc
aatggaagatcaacaggcttgaacgcagtcccatctcaaatccttgaagggcagtgggct
gctcgaagcatgccaccaagctttggctattcaatgaaaggagccacagatatagacaaa
aatggatatccagacttaattgtaggagcttttggtgtagatcgagctatcttatacagg
gccagaccagttatcactgtaaatgctggtcttgaagtgtaccctagcattttaaatcaa
gacaataaaacctgctcactgcctggaacagctctcaaagtttcctgttttaatgttagg
ttctgcttaaaggcagatggcaaaggagtacttcccaggaaacttaatttccaggtggaa
cttcttttggataaactcaagcaaaagggagcaattcgacgagcactgtttctctacagc
aggtccccaagtcactccaagaacatgactatttcaagggggggactgatgcagtgtgag
gaattgatagcgtatctgcgggatgaatctgaatttagagacaaactcactccaattact
atttttatggaatatcggttggattatagaacagctgctgatacaacaggcttgcaaccc
attcttaaccagttcacgcctgctaacattagtcgacaggctcacattctacttgactgt
ggtgaagacaatgtctgtaaacccaagctggaagtttctgtagatagtgatcaaaagaag
atctatattggggatgacaaccctctgacattgattgttaaggctcagaatcaaggagaa
ggtgcctacgaagctgagctcatcgtttccattccactgcaggctgatttcatcggggtt
gtccgaaacaatgaagccttagcaagactttcctgtgcatttaagacagaaaaccaaact
cgccaggtggtatgtgaccttggaaacccaatgaaggctggaactcaactcttagctggt
cttcgtttcagtgtgcaccagcagtcagagatggatacttctgtgaaatttgacttacaa
atccaaagctcaaatctatttgacaaagtaagcccagttgtatctcacaaagttgatctt
gctgttttagctgcagttgagataagaggagtctcgagtcctgatcatatctttcttccg
attccaaactgggagcacaaggagaaccctgagactgaagaagatgttgggccagttgtt
cagcacatctatgagctgagaaacaatggtccaagttcattcagcaaggcaatgctccat
cttcagtggccttacaaatataataataacactctgttgtatatccttcattatgatatt
gatggaccaatgaactgcacttcagatatggagatcaaccctttgagaattaagatctca
tctttgcaaacaactgaaaagaatgacacggttgccgggcaaggtgagcgggaccatctc
atcactaagcgggatcttgccctcagtgaaggagatattcacactttgggttgtggagtt
gctcagtgcttgaagattgtctgccaagttgggagattagacagaggaaagagtgcaatc
ttgtacgtaaagtcattactgtggactgagacttttatgaataaagaaaatcagaatcat
tcctattctctgaagtcgtctgcttcatttaatgtcatagagtttccttataagaatctt
ccaattgaggatatcaccaactccacattggttaccactaatgtcacctggggcattcag
ccagcgcccatgcctgtgcctgtgtgggtgatcattttagcagttctagcaggattgttg
ctactggctgttttggtatttgtaatgtacaggatgggcttttttaaacgggtccggcca
cctcaagaagaacaagaaagggagcagcttcaacctcatgaaaatggtgaaggaaactca
gaaacttaa

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