KEGG   Homo sapiens (human): 3949Help
Entry
3949              CDS       T01001                                 

Gene name
LDLR, FH, FHC, LDLCQ2
Definition
low density lipoprotein receptor
Orthology
K12473  
low-density lipoprotein receptor
Organism
hsa  Homo sapiens (human)
Pathway
Endocytosis
Ovarian steroidogenesis
Bile secretion
Toxoplasmosis
Hepatitis C
Disease
H00155  
Hypercholesterolemia
Class
Cellular Processes; Transport and catabolism; Endocytosis [PATH:hsa04144]
Organismal Systems; Endocrine system; Ovarian Steroidogenesis [PATH:hsa04913]
Organismal Systems; Digestive system; Bile secretion [PATH:hsa04976]
Human Diseases; Infectious diseases; Hepatitis C [PATH:hsa05160]
Human Diseases; Infectious diseases; Toxoplasmosis [PATH:hsa05145]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
19p13.2
AA seq 860 aa AA seqDB search
MGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQ
ETCLSVTCKSGDFSCGGRVNRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGK
CISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEW
PQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDE
FQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMAR
DCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQD
PDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYT
SLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLA
VDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPA
KIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILE
DEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQ
PRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAEAAVA
TQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQALGDVAGRGN
EKKPSSVRALSIVLPIVLLVFLCLGVFLLWKNWRLKNINSINFDNPVYQKTTEDEVHICH
NQDGYSYPSRQMVSLEDDVA
NT seq 2583 nt NT seq  +upstreamnt  +downstreamnt
atggggccctggggctggaaattgcgctggaccgtcgccttgctcctcgccgcggcgggg
actgcagtgggcgacagatgcgaaagaaacgagttccagtgccaagacgggaaatgcatc
tcctacaagtgggtctgcgatggcagcgctgagtgccaggatggctctgatgagtcccag
gagacgtgcttgtctgtcacctgcaaatccggggacttcagctgtgggggccgtgtcaac
cgctgcattcctcagttctggaggtgcgatggccaagtggactgcgacaacggctcagac
gagcaaggctgtccccccaagacgtgctcccaggacgagtttcgctgccacgatgggaag
tgcatctctcggcagttcgtctgtgactcagaccgggactgcttggacggctcagacgag
gcctcctgcccggtgctcacctgtggtcccgccagcttccagtgcaacagctccacctgc
atcccccagctgtgggcctgcgacaacgaccccgactgcgaagatggctcggatgagtgg
ccgcagcgctgtaggggtctttacgtgttccaaggggacagtagcccctgctcggccttc
gagttccactgcctaagtggcgagtgcatccactccagctggcgctgtgatggtggcccc
gactgcaaggacaaatctgacgaggaaaactgcgctgtggccacctgtcgccctgacgaa
ttccagtgctctgatggaaactgcatccatggcagccggcagtgtgaccgggaatatgac
tgcaaggacatgagcgatgaagttggctgcgttaatgtgacactctgcgagggacccaac
aagttcaagtgtcacagcggcgaatgcatcaccctggacaaagtctgcaacatggctaga
gactgccgggactggtcagatgaacccatcaaagagtgcgggaccaacgaatgcttggac
aacaacggcggctgttcccacgtctgcaatgaccttaagatcggctacgagtgcctgtgc
cccgacggcttccagctggtggcccagcgaagatgcgaagatatcgatgagtgtcaggat
cccgacacctgcagccagctctgcgtgaacctggagggtggctacaagtgccagtgtgag
gaaggcttccagctggacccccacacgaaggcctgcaaggctgtgggctccatcgcctac
ctcttcttcaccaaccggcacgaggtcaggaagatgacgctggaccggagcgagtacacc
agcctcatccccaacctgaggaacgtggtcgctctggacacggaggtggccagcaataga
atctactggtctgacctgtcccagagaatgatctgcagcacccagcttgacagagcccac
ggcgtctcttcctatgacaccgtcatcagcagagacatccaggcccccgacgggctggct
gtggactggatccacagcaacatctactggaccgactctgtcctgggcactgtctctgtt
gcggataccaagggcgtgaagaggaaaacgttattcagggagaacggctccaagccaagg
gccatcgtggtggatcctgttcatggcttcatgtactggactgactggggaactcccgcc
aagatcaagaaagggggcctgaatggtgtggacatctactcgctggtgactgaaaacatt
cagtggcccaatggcatcaccctagatctcctcagtggccgcctctactgggttgactcc
aaacttcactccatctcaagcatcgatgtcaacgggggcaaccggaagaccatcttggag
gatgaaaagaggctggcccaccccttctccttggccgtctttgaggacaaagtattttgg
acagatatcatcaacgaagccattttcagtgccaaccgcctcacaggttccgatgtcaac
ttgttggctgaaaacctactgtccccagaggatatggttctcttccacaacctcacccag
ccaagaggagtgaactggtgtgagaggaccaccctgagcaatggcggctgccagtatctg
tgcctccctgccccgcagatcaacccccactcgcccaagtttacctgcgcctgcccggac
ggcatgctgctggccagggacatgaggagctgcctcacagaggctgaggctgcagtggcc
acccaggagacatccaccgtcaggctaaaggtcagctccacagccgtaaggacacagcac
acaaccacccgacctgttcccgacacctcccggctgcctggggccacccctgggctcacc
acggtggagatagtgacaatgtctcaccaagctctgggcgacgttgctggcagaggaaat
gagaagaagcccagtagcgtgagggctctgtccattgtcctccccatcgtgctcctcgtc
ttcctttgcctgggggtcttccttctatggaagaactggcggcttaagaacatcaacagc
atcaactttgacaaccccgtctatcagaagaccacagaggatgaggtccacatttgccac
aaccaggacggctacagctacccctcgagacagatggtcagtctggaggatgacgtggcg
tga

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