KEGG T01001: 3980

Homo sapiens (human): 3980

Entry

3980 CDS T01001

Gene name

LIG3, LIG2

Definition

ligase III, DNA, ATP-dependent (EC:6.5.1.1)

Orthology

K10776

DNA ligase 3 [EC:6.5.1.1]

Organism

hsa Homo sapiens (human)

Pathway

hsa03410

Base excision repair

Module

hsa_M00296

BER complex

Class

Genetic Information Processing; Replication and repair; Base excision repair [PATH:hsa03410]

SSDB

Motif

Pfam:

DNA_ligase_A_M DNA_ligase_A_N zf-PARP DNA_ligase_A_C Synaptonemal_3 mRNA_cap_enzyme DUF3195 FAD_binding_1 Sec1

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

3L2P 1UW0

Position

17q11.2-q12

AA seq 949 aa
MSLAFKIFFPQTLRALSRKELCLFRKHHWRDVRQFSQWSETDLLHGHPLFLRRKPVLSFQ
GSHLRSRATYLVFLPGLHVGLCSGPCEMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIG
KVVPNPFSESGGDMKEWYHIKCMFEKLERARATTKKIEDLTELEGWEELEDNEKEQITQH
IADLSSKAAGTPKKKAVVQAKLTTTGQVTSPVKGASFVTSTNPRKFSGFSAKPNNSGEAP
SSPTPKRSLSSSKCDPRHKDCLLREFRKLCAMVADNPSYNTKTQIIQDFLRKGSAGDGFH
GDVYLTVKLLLPGVIKTVYNLNDKQIVKLFSRIFNCNPDDMARDLEQGDVSETIRVFFEQ
SKSFPPAAKSLLTIQEVDEFLLRLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHDL
KMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEVEKEPGQRRALSVQASLMTP
VQPMLAEACKSVEYAMKKCPNGMFSEIKYDGERVQVHKNGDHFSYFSRSLKPVLPHKVAH
FKDYIPQAFPGGHSMILDSEVLLIDNKTGKPLPFGTLGVHKKAAFQDANVCLFVFDCIYF
NDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEMKRVTKALDLADMITRVIQEGLEGLVLK
DVKGTYEPGKRHWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPGS
QKWCTVTKCAGGHDDATLARLQNELDMVKISKDPSKIPSWLKVNKIYYPDFIVPDPKKAA
VWEITGAEFSKSEAHTADGISIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEKADFTV
VAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPS
AMKVGEKLATKSSPVKVGEKRKAADETLCQTKRRPASEQRGRTVPAGRR

NT seq 2850 nt +upstreamnt +downstreamnt
atgtctttggctttcaagatcttctttccacaaaccctccgtgcactcagccgaaaagaa
ctgtgcctattccgaaaacatcactggcgtgatgtaagacaattcagccagtggtcagaa
acagatctgcttcatggacatcccctcttcctgagaagaaagcctgttctatcattccag
ggaagccatctaagatcacgtgccacctaccttgttttcttgccagggttgcatgtggga
ctctgcagtggcccctgtgagatggctgagcaacggttctgtgtggactatgccaagcgt
ggcacagctggctgcaaaaaatgcaaggaaaagattgtgaagggcgtatgccgaattggc
aaagtggtgcccaatcccttctcagagtctgggggtgatatgaaagagtggtaccacatt
aaatgcatgtttgagaaactagagcgggcccgggccaccacaaaaaaaatcgaggacctc
acagagctggaaggctgggaagagctggaagataatgagaaggaacagataacccagcac
attgcagatctgtcttctaaggcagcaggtacaccaaagaagaaagctgttgtccaggct
aagttgacaaccactggccaggtgacttctccagtgaaaggcgcctcatttgtcaccagt
accaatccccggaaattttctggcttttcagccaagcccaacaactctggggaagccccc
tcgagccccacccctaagagaagtctgtcttcaagcaaatgtgaccccaggcataaggac
tgtctgctacgggagtttcgaaagttatgcgccatggtggccgataatcctagctacaac
acgaagacccagatcatccaggacttccttcggaaaggctcagcaggagatggtttccac
ggtgatgtgtacctaacagtgaagctgctgctgccaggagtcattaagactgtttacaac
ttgaacgataagcagattgtgaagcttttcagtcgcatttttaactgcaacccagatgat
atggcacgggacctagagcagggtgacgtgtcagagacaatcagagtcttctttgagcag
agcaagtctttccccccagctgccaagagcctccttaccatccaggaagtggatgagttc
cttctgcggctgtccaagctcaccaaggaggatgagcagcaacaggccctacaggacatt
gcctccaggtgtacagccaatgaccttaaatgcatcatcaggttgatcaaacatgatctg
aagatgaactcaggtgcaaaacatgtgttagacgcccttgaccccaatgcctatgaagcc
ttcaaagcctcgcgcaacctgcaggatgtggtggagcgggtccttcacaacgcgcaggag
gtggagaaggagccgggccagagacgagctctgagcgtccaggcctcgctgatgacacct
gtgcagcccatgttggcggaggcctgcaagtccgttgagtatgcaatgaagaaatgtccc
aatggcatgttctctgagatcaagtacgatggagagcgagtccaggtgcataagaatgga
gaccacttcagctacttcagccgcagtctcaagcccgtccttcctcacaaggtggcccac
tttaaggactacattccccaggcttttcctgggggccacagcatgatcttggattctgaa
gtgcttctgattgacaacaagacaggcaaaccactgccctttgggactctgggagtacac
aagaaagcagccttccaggatgctaatgtctgcctgtttgtttttgattgtatctacttt
aatgatgtcagcttgatggacagacctctgtgtgagcggcggaagtttcttcatgacaac
atggttgaaattccaaaccggatcatgttctcagaaatgaagcgagtcacaaaagctttg
gacttggctgacatgataacccgggtgatccaggagggattggaggggctggtgctgaag
gatgtgaagggtacatatgagcctgggaagcggcactggctgaaagtgaagaaagactat
ttgaacgagggggccatggccgacacagctgacctggtggtccttggagccttctatggg
caagggagcaaaggcggcatgatgtcaatcttcctcatgggctgctacgaccctggcagc
cagaagtggtgcacagtcaccaagtgtgcaggaggccatgatgatgccacgcttgcccgc
ctgcagaatgaactagacatggtgaagatcagcaaggaccccagcaaaatacccagctgg
ttgaaggtcaacaagatctactatcctgacttcatcgtcccagacccaaagaaagctgcc
gtgtgggagatcacaggggctgaattctccaaatcggaggctcatacagctgacgggatc
tccatccgattccctcgctgcacccgaatccgagatgataaggactggaaatctgccact
aaccttccccaactcaaggaactgtaccagttgtccaaggagaaggcagacttcactgta
gtggctggagatgaggggagctccactacagggggtagcagtgaagagaataagggtccc
tcagggtctgctgtgtcccgcaaggcccccagcaagccctcagccagtaccaagaaagca
gaagggaagctgagtaactccaacagcaaagatggcaacatgcagactgcaaagccttcc
gctatgaaggtgggggagaagctggccacaaagtcttctccagtgaaagtaggggagaag
cggaaagctgctgatgagacgctgtgccaaacaaagaggcggccagccagtgagcagaga
ggaagaactgtgccagcaggcaggagatag

All links

Pathway (2)   
   KEGG PATHWAY (1)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (6)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (3)   
   RefSeq(pep) (2)   
DNA sequence (30)   
   RefSeq(nuc) (2)   
   GenBank (14)   
   EMBL (14)   
3D Structure (2)   
   PDB (2)   
Protein domain (9)   
   Pfam (9)   
All databases (65)   

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