KEGG   Homo sapiens (human): 4077
Entry
4077              CDS       T01001                                 
Symbol
NBR1, 1A1-3B, IAI3B, M17S2, MIG19
Name
(RefSeq) NBR1 autophagy cargo receptor
  KO
K17987  next to BRCA1 gene 1 protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa04137  Mitophagy - animal
hsa04140  Autophagy - animal
Network
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
nt06532  Autophagy
nt06536  Mitophagy
  Element
N01137  PINK-Parkin-mediated autophagosome formation
N01140  TBK1-mediated autophagosome formation
N01141  Mutation-inactivated TBK1 to TBK1-mediated autophagosome formation
N01716  Autophagy-vesicle nucleation/elongation/maturation, sequestosome-1-like receptor
N01756  PINK-Parkin-independent ubiquitin-mediated mitophagy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    4077 (NBR1)
   04137 Mitophagy - animal
    4077 (NBR1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    4077 (NBR1)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    4077 (NBR1)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    4077 (NBR1)
  Pexophagy
   Other pexophagy associated proteins
    4077 (NBR1)
  Aggrephagy
   Cargo receptors
    4077 (NBR1)
  Xenophagy
    4077 (NBR1)
  Other autophagy associated proteins
   Midbophagy
    4077 (NBR1)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Other mitophagy factors
    4077 (NBR1)
SSDB
Motif
Pfam: N_BRCA1_IG PB1 ZZ CENP-B_dimeris Sgf11
Other DBs
NCBI-GeneID: 4077
NCBI-ProteinID: NP_005890
OMIM: 166945
HGNC: 6746
Ensembl: ENSG00000188554
UniProt: Q14596
Structure
Position
17:43170409..43211688
AA seq 966 aa
MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
WYSQRY
NT seq 2901 nt   +upstreamnt  +downstreamnt
atggaaccacaggttactctaaatgtgacttttaaaaatgaaattcaaagctttctggtt
tctgatccagaaaatacaacttgggctgatatcgaagctatggtaaaagtttcatttgat
ctgaatactattcaaataaaatacctggatgaggaaaatgaagaggtatccatcaacagt
caaggagaatatgaagaagcgcttaagatggcagttaaacagggaaaccaactgcagatg
caagtccacgaagggcaccatgtcgttgatgaagccccacccccagttgtaggagcaaaa
cgactagctgccagggcagggaagaagccacttgcacattactcttcactggtgagagtc
ttgggatcagacatgaagaccccagaggatcctgcagtgcagtcgtttccacttgttcca
tgtgacacagaccagcctcaagacaagcccccagactggttcacaagctacctggagacg
ttcagagaacaagtggttaacgaaacggttgagaagcttgaacagaaattacatgaaaag
cttgtcctccagaacccatccttgggttcttgtccctcagaagtctcaatgcctacttca
gaagaaacattgtttttgccagaaaaccagttcagctggcatattgcttgcaacaactgc
caaagaaggattgttggtgtccgctaccagtgtagcctatgcccatcctacaatatctgt
gaagattgtgaagcagggccatatggccatgacactaaccacgtcctgctgaagttgcgg
agacctgttgtgggctcctctgaaccgttctgtcactcaaagtactctactcctcgtctt
cctgctgctctggaacaagtcaggctccagaaacaggttgataagaactttcttaaagca
gaaaagcaaaggttgcgagctgagaagaaacaacgtaaagcagaggtcaaggaacttaaa
aagcagcttaaactccataggaaaattcacctgtggaattcaatccatggactccagagc
cccaagtctcctttaggccgacctgagagcttgctccagtctaataccctgatgctccct
ttgcagccctgtacctccgttatgccaatgctcagtgcagcatttgtggatgagaatttg
cctgatgggactcaccttcagccaggaaccaagtttatcaaacactggaggatgaaaaat
acaggaaatgtaaagtggagtgcagacacaaagctcaagttcatgtggggaaacctgact
ttggcttccacagaaaagaaggatgttttggttccctgcctcaaggccggccatgtggga
gttgtatctgtggagttcattgccccagccttggagggaacgtatacttcccattggcgt
ctttctcacaaaggccagcaatttgggcctcgggtctggtgcagtatcatagtagatcct
ttcccctccgaagagagccctgataacattgaaaagggcatgatcagctcaagcaaaact
gatgatctcacctgccagcaagaggaaacttttcttctggctaaagaagaaagacagctt
ggtgaagtgactgagcagacagaagggacagcagcctgcatcccacagaaggcaaaaaat
gttgccagtgagagggagctctacatcccatctgtggatcttctgactgcccaggacctg
ctgtcctttgagctgttggatataaacattgttcaagagttggagagagtgccccacaac
acccctgtggatgtgactccctgcatgtctcctctgccacatgacagtcctttaatagag
aagccaggcttggggcagatagaggaagagaatgaaggggcaggatttaaagcacttcct
gattctatggtgtcagtaaagaggaaggctgagaacattgcttctgtggaggaagcagaa
gaagacctgagtgggacccagtttgtgtgtgagacagtaatccgatcccttaccttggat
gctgccccagaccacaaccctccttgcagacagaagtccttgcagatgacatttgccttg
cctgaaggaccacttggaaatgagaaggaggagattatccatatcgctgaggaagaagct
gtcatggaggaggaggaggatgaggaggatgaggaggaggaggatgagctcaaagatgaa
gttcaaagtcagtcctctgcttcctcagaggattacatcatcatcctgcctgagtgcttt
gataccagccgccccctgggggattctatgtacagctctgcgctctcacagccaggcctg
gagcgaggtgctgaaggcaagcctggggttgaggctgggcaggaaccagctgaggctggg
gaaagactccctggaggggagaaccagccacaggagcacagcataagtgacatcctcacg
acctcacagactctggaaacagtgcccctaatcccagaggtagtggagcttccaccgtca
ctgcccaggagctctccttgtgtacatcatcatggttccccaggagtggatttaccagtt
accataccagaagtttcttcagtccctgatcagatcagaggagagcccagaggctcatca
ggacttgtaaacagcagacagaagagctatgaccactcaaggcaccatcatgggagcagc
attgctggaggactggtgaagggggctttgtctgttgctgcctctgcatacaaggccctg
tttgctgggccaccagtcactgcacagccaataatttctgaagatcagacagcagccctg
atggcccatctctttgaaatgggattctgtgacaggcagctgaacctacggctgctgaag
aaacacaattacaatatcctgcaggttgtgacagaacttcttcagttaaacaacaacgac
tggtacagccaacgctattga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (9)   
   KEGG NETWORK (9)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (16)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (49)   
   RefSeq(nuc) (15)   
   GenBank (17)   
   EMBL (17)   
3D Structure (8)   
   PDB (8)   
Protein domain (5)   
   Pfam (5)   
All databases (116)   

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