KEGG T01001: 4122

Homo sapiens (human): 4122

Entry

4122 CDS T01001

Gene name

MAN2A2, MANA2X

Definition

mannosidase, alpha, class 2A, member 2 (EC:3.2.1.114)

Orthology

K01231

alpha-mannosidase II [EC:3.2.1.114]

Organism

hsa Homo sapiens (human)

Pathway

hsa00510	N-Glycan biosynthesis
hsa01100	Metabolic pathways

Module

hsa_M00075

N-glycan biosynthesis, complex type

Class

Metabolism; Glycan biosynthesis and metabolism; N-Glycan biosynthesis [PATH:hsa00510]

SSDB

Motif

Pfam:

Glyco_hydro_38 Glyco_hydro_38C Alpha-mann_mid

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

UniProt:

Position

15q26.1

AA seq 1150 aa
MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPTRHQNGGNFPRSQISVLQNRIEQLEQL
LEENHEIISHIKDSVLELTANAEGPPAMLPYYTVNGSWVVPPEPRPSFFSISPQDCQFAL
GGRGQKPELQMLTVSEELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHNDPGW
IKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGN
GQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDPFGYSSTMPYL
LRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVPHTC
GPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLL
VPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNLHVQAQFGTLSDYFDALYKRTGVEPG
ARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHAR
RSGLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVII
HAAHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRFVVLFNPLEQER
FSMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQL
QLGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGL
LKSIRRVDEEHEQQVDMQVLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPF
FSEVVAYYEHIHQAVRLYNLPGVEGLSLDISSLVDIRDYVNKELALHIHTDIDSQGIFFT
DLNGFQVQPRRYLKKLPLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVIL
DRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSEVQDSHSTSYPSLLSHLTSMYLN
APALALPVARMQLPGPGLRSFHPLASSLPCDFHLLNLRTLQAEEDTLPSAETALILHRKG
FDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYLEPM
EIATFRLRLG

NT seq 3453 nt +upstreamnt +downstreamnt
atgaagctgaaaaagcaggtgacagtgtgtggggctgccatcttctgtgtggcagtcttc
tcgctctacctcatgctggaccgagtgcaacacgatcccacccgacaccagaatggtggg
aacttcccccggagccaaatttctgtgctgcagaaccgcattgagcagctggagcagctt
ttggaggagaaccatgagattatcagccatatcaaggactccgtgctggagctgacagcc
aacgcagagggcccgcccgccatgctgccctactacacggtcaatggctcctgggtggtg
ccaccggagccccggcccagcttcttctccatctccccgcaggactgccagtttgctttg
gggggccggggtcagaagccagagctgcagatgctcactgtgtcggaggagctgccgttt
gacaacgtggatggtggtgtgtggaggcaaggcttcgacatctcctacgacccgcacgac
tgggatgctgaagacctgcaggtgtttgtggtgccccactctcacaatgacccaggctgg
atcaagacctttgacaagtactacacagagcagacccaacacatcctcaatagcatggtg
tctaagctgcaggaggacccccggcggcgcttcctctgggcagaggtctccttcttcgcc
aagtggtgggacaacatcaatgtccaaaagagagcggcagtccgaaggctggtgggaaac
gggcagctggagattgcgacaggaggctgggtgatgccagatgaggccaattcccactac
tttgcattgattgaccagctcatcgaaggacaccagtggctggagagaaatcttggtgca
accccccgctctggctgggcagtggacccctttggatacagctccaccatgccttacctg
ctgcgccgtgccaacctcaccagcatgctgattcagagagtgcactatgccatcaagaag
cactttgctgccacccacagcctagagttcatgtggaggcagacatgggactcggactcc
agcacagacatcttctgtcacatgatgcccttctacagctatgacgtcccccatacctgt
ggcccagatcccaagatctgctgccaatttgatttcaaacgcctgcctggtgggcgcatc
aactgcccttggaaggtgccaccccgggccatcacagaggccaacgtggcagagagggca
gccctgcttctggaccaataccggaagaagtcccagctgttccgaagcaacgtcctcctg
gtgcctcttggagatgacttccgatatgacaagccccaggagtgggatgcccagttcttc
aactaccaacggctctttgacttcttcaacagcaggcctaacctccatgtgcaggcccag
tttggcactctttctgactattttgatgccctgtacaagaggacaggggtggagccaggg
gcccggcctccagggtttcctgtgctgagcggggatttcttctcctatgcggaccgggag
gatcattactggacaggctattacacttcccggcccttctacaagagcttagaccgagtc
ctggaagcccacctgcggggggcagaggttctgtacagcctggctgcagctcacgctcgc
cgctctggtctggctggccggtacccactgtctgatttcaccctcctgacggaagctcgg
cgcacattggggctcttccagcatcacgatgccatcactggcacggccaaggaggctgtg
gtggtggactatggggtcaggcttctgcgctcccttgtcaacctgaagcaggtcatcatt
catgcagcccactatctggtgctgggggacaaggagacctaccactttgaccctgaggcg
cccttcctccaagtggatgacactcgcttaagtcacgacgccctcccagagcgcacggtg
atccagctggattcctcgcccaggtttgtggtcctattcaacccactggaacaggagcga
ttcagcatggtgtccctgctggtcaactctccccgcgtgcgtgtcctttcggaggagggt
cagcccctggccgtgcagatcagcgcacactggagctctgccaccgaggcggtccctgac
gtctaccaggtgtctgtgcctgtccgcctgccagccctgggcctgggcgtgctgcagcta
cagctgggcctggatgggcaccgcacgctgccctcctctgtgcgcatctacctgcacggc
cggcagctgtccgtcagcaggcacgaagcgtttcctctccgtgtcattgactctggcacc
agcgacttcgccctcagcaaccgctacatgcaggtctggttctcaggccttactgggctc
ctcaagagcatccgaagggtggatgaggagcacgagcagcaggtggacatgcaggtcctt
gtctatggcacccgtacgtccaaagacaagagtggagcctacctcttcctgcccgatggc
gaggccaagccctacgtccccaaggagccccccgtgctgcgtgtcactgaaggccctttc
ttctcagaggtggttgcgtactatgagcacattcaccaggcggtccggctttacaatctg
ccaggggtggaggggctgtctctggacatatcatccctggtggacatccgggactacgtc
aacaaggagctggccctgcacatccatacagacatcgacagccagggtatcttcttcaca
gacctcaatggctttcaggtgcagccccgacggtatctgaagaagctccccctccaggcc
aacttctaccccatgccagtcatggcctatatccaggacgcacagaagcgcctcacgctg
cacactgcccaggccctgggtgtctctagcctcaaagatggccagctggaggtgatcttg
gaccggcggctgatgcaggatgacaaccggggcctaggccaagggctcaaggacaacaag
agaacctgcaaccgtttccgcctcctgctagagcggcgaaccgtgggcagtgaggtccaa
gatagccactctaccagctacccatccctcctcagccacctgacctccatgtacctgaac
gccccggcgctcgctctgcctgtagccaggatgcagctcccaggccctggtctgcgctca
tttcatcctctggcttcctcactgccctgtgacttccacctgctcaacctacgtacgctc
caggctgaggaggacaccctaccctcggcggagaccgcactcatcttacaccgcaagggt
tttgactgcggcctggaggccaagaacttgggcttcaactgcaccacaagccaaggcaag
gtagccctgggcagccttttccatggcctggatgtggtattccttcagccaacctccttg
acgttactgtaccctctggcctccccgtccaacagcactgacgtctatttggagcccatg
gagattgctacctttcgcctccgcttgggttag

All links

Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (10)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (33)   
   RefSeq(nuc) (1)   
   GenBank (16)   
   EMBL (16)   
Protein domain (3)   
   Pfam (3)   
All databases (65)   

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