KEGG T01001: 4296

Homo sapiens (human): 4296

Entry

4296 CDS T01001

Gene name

MAP3K11, MEKK11, MLK-3, MLK3, PTK1, SPRK

Definition

mitogen-activated protein kinase kinase kinase 11 (EC:2.7.11.25)

Orthology

K04419

mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]

Organism

hsa Homo sapiens (human)

Pathway

hsa04010

MAPK signaling pathway

Class

Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:hsa04010]

SSDB

Motif

Pfam:

Pkinase_Tyr Pkinase SH3_9 SH3_2 SH3_1 DUF4393 APG6

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

11q13.1-q13.3

AA seq 847 aa
MEPLKSLFLKSPLGSWNGSGSGGGGGGGGGRPEGSPKAAGYANPVWTALFDYEPSGQDEL
ALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSRGGGPPPCEVASFQELRLE
EVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIALK
AVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHR
DLKSNNILLLQPIESDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVIKASTFS
KGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWA
QDPHRRPDFASILQQLEALEAQVLREMPRDSFHSMQEGWKREIQGLFDELRAKEKELLSR
EEELTRAAREQRSQAEQLRRREHLLAQWELEVFERELTLLLQQVDRERPHVRRRRGTFKR
SKLRARDGGERISMPLDFKHRITVQASPGLDRRRNVFEVGPGDSPTFPRFRAIQLEPAEP
GQAWGRQSPRRLEDSSNGERRACWAWGPSSPKPGEAQNGRRRSRMDEATWYLDSDDSSPL
GSPSTPPALNGNPPRPSLEPEEPKRPVPAERGSSSGTPKLIQRALLRGTALLASLGLGRD
LQPPGGPGRERGESPTTPPTPTPAPCPTEPPPSPLICFSLKTPDSPPTPAPLLLDLGIPV
GQRSAKSPRREEEPRGGTVSPPPGTSRSAPGTPGTPRSPPLGLISRPRPSPLRSRIDPWS
FVSAGPRPSPLPSPQPAPRRAPWTLFPDSDPFWDSPPANPFQGGPQDCRAQTKDMGAQAP
WVPEAGP

NT seq 2544 nt +upstreamnt +downstreamnt
atggagcccttgaagagcctcttcctcaagagccctctagggtcatggaatggcagtggc
agcgggggtggtgggggcggtggaggaggccggcctgaggggtctccaaaggcagcgggt
tatgccaacccggtgtggacagccctgttcgactacgagcccagtgggcaggatgagctg
gccctgaggaagggtgaccgtgtggaggtgctgtcccgggacgcagccatctcaggagac
gagggctggtgggcgggccaggtgggtggccaggtgggcatcttcccgtccaactatgtg
tctcggggtggcggcccgcccccctgcgaggtggccagcttccaggagctgcggctggag
gaggtgatcggcattggaggctttggcaaggtgtacaggggcagctggcgaggtgagctg
gtggctgtgaaggcagctcgccaggaccccgatgaggacatcagtgtgacagccgagagc
gttcgccaggaggcccggctcttcgccatgctggcacaccccaacatcattgccctcaag
gctgtgtgcctggaggagcccaacctgtgcctggtgatggagtatgcagccggtgggccc
ctcagccgagctctggccgggcggcgcgtgcctccccatgtgctggtcaactgggctgtg
cagattgcccgtgggatgcactacctgcactgcgaggccctggtgcccgtcatccaccgt
gatctcaagtccaacaacattttgctgctgcagcccattgagagtgacgacatggagcac
aagaccctgaagatcaccgactttggcctggcccgagagtggcacaaaaccacacaaatg
agtgccgcgggcacctacgcctggatggctcctgaggttatcaaggcctccaccttctct
aagggcagtgacgtctggagttttggggtgctgctgtgggaactgctgaccggggaggtg
ccataccgtggcattgactgccttgctgtggcctatggcgtagctgttaacaagctcaca
ctgcccatcccatccacctgccccgagcccttcgcacagcttatggccgactgctgggcg
caggacccccaccgcaggcccgacttcgcctccatcctgcagcagttggaggcgctggag
gcacaggtcctacgggaaatgccgcgggactccttccattccatgcaggaaggctggaag
cgcgagatccagggtctcttcgacgagctgcgagccaaggaaaaggaactactgagccgc
gaggaggagctgacgcgagcggcgcgcgagcagcggtcacaggcggagcagctgcggcgg
cgcgagcacctgctggcccagtgggagctagaggtgttcgagcgcgagctgacgctgctg
ctgcagcaggtggaccgcgagcgaccgcacgtgcgccgccgccgcgggacattcaagcgc
agcaagctccgggcgcgcgacggcggcgagcgtatcagcatgccactcgacttcaagcac
cgcatcaccgtgcaggcctcacccggccttgaccggaggagaaacgtcttcgaggtcggg
cctggggattcgcccacctttccccggttccgagccatccagttggagcctgcagagcca
ggccaggcatggggccgccagtccccccgacgtctggaggactcaagcaatggagagcgg
cgagcatgctgggcttggggtcccagttcccccaagcctggggaagcccagaatgggagg
agaaggtcccgcatggacgaagccacatggtacctggattcagatgactcatccccctta
ggatctccttccacacccccagcactcaatggtaaccccccgcggcctagcctggagccc
gaggagcccaagaggcctgtccccgcagagcgcggtagcagctctgggacgcccaagctg
atccagcgggcgctgctgcgcggcaccgccctgctcgcctcgctgggccttggccgcgac
ctgcagccgccgggaggcccaggacgcgagcgcggggagtccccgacaacaccccccacg
ccaacgcccgcgccctgcccgaccgagccgcccccttccccgctcatctgcttctcgctc
aagacgcccgactccccgcccactcctgcacccctgttgctggacctgggtatccctgtg
ggccagcggtcagccaagagcccccgacgtgaggaggagccccgcggaggcactgtctca
cccccaccggggacatcacgctctgctcctggcaccccaggcaccccacgttcaccaccc
ctgggcctcatcagccgacctcggccctcgccccttcgcagccgcattgatccctggagc
tttgtgtcagctgggccacggccttctcccctgccatcaccacagcctgcaccccgccga
gcaccctggaccttgttcccggactcagaccccttctgggactccccacctgccaacccc
ttccaggggggcccccaggactgcagggcacagaccaaagacatgggtgcccaggccccg
tgggtgccggaagcggggccttga

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (12)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (27)   
   RefSeq(nuc) (1)   
   GenBank (13)   
   EMBL (13)   
Protein domain (7)   
   Pfam (7)   
All databases (60)   

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