KEGG T01001: 4312

Homo sapiens (human): 4312

Entry

4312 CDS T01001

Gene name

MMP1, CLG, CLGN

Definition

matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)

Orthology

K01388

matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]

Organism

hsa Homo sapiens (human)

Pathway

hsa03320	PPAR signaling pathway
hsa05200	Pathways in cancer
hsa05219	Bladder cancer
hsa05323	Rheumatoid arthritis

Disease

H00028

Choriocarcinoma

Drug target

Other:

D03517

Class

Organismal Systems; Endocrine system; PPAR signaling pathway [PATH:hsa03320]
Human Diseases; Cancers; Pathways in cancer [PATH:hsa05200]
Human Diseases; Cancers; Bladder cancer [PATH:hsa05219]
Human Diseases; Immune diseases; Rheumatoid arthritis [PATH:hsa05323]

SSDB

Motif

Pfam:

Peptidase_M10 Hemopexin PG_binding_1 Astacin Reprolysin_3 Reprolysin_5 Reprolysin_2 Peptidase_M54 Reprolysin_4 Peptidase_M66

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

1HFC 966C 1CGE 1CGF 3SHI 1SU3 2TCL 1CGL 2J0T 2CLT 4AUO 3AYK 4AYK 1AYK 2AYK

Position

11q22.3

AA seq 403 aa
MQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLP
RADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQ
PGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDV
QLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDRFYMRTN
PFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYS
SFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKV
DAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN

NT seq 1212 nt +upstreamnt +downstreamnt
atgcaggaattctttgggctgaaagtgactgggaaaccagatgctgaaaccctgaaggtg
atgaagcagcccagatgtggagtgcctgatgtggctcagtttgtcctcactgaggggaac
cctcgctgggagcaaacacatctgacctacaggattgaaaattacacgccagatttgcca
agagcagatgtggaccatgccattgagaaagccttccaactctggagtaatgtcacacct
ctgacattcaccaaggtctctgagggtcaagcagacatcatgatatcttttgtcagggga
gatcatcgggacaactctccttttgatggacctggaggaaatcttgctcatgcttttcaa
ccaggcccaggtattggaggggatgctcattttgatgaagatgaaaggtggaccaacaat
ttcagagagtacaacttacatcgtgttgcagctcatgaactcggccattctcttggactc
tcccattctactgatatcggggctttgatgtaccctagctacaccttcagtggtgatgtt
cagctagctcaggatgacattgatggcatccaagccatatatggacgttcccaaaatcct
gtccagcccatcggcccacaaaccccaaaagcgtgtgacagtaagctaacctttgatgct
ataactacgattcggggagaagtgatgttctttaaagacagattctacatgcgcacaaat
cccttctacccggaagttgagctcaatttcatttctgttttctggccacaactgccaaat
gggcttgaagctgcttacgaatttgccgacagagatgaagtccggtttttcaaagggaat
aagtactgggctgttcagggacagaatgtgctacacggataccccaaggacatctacagc
tcctttggcttccctagaactgtgaagcatatcgatgctgctctttctgaggaaaacact
ggaaaaacctacttctttgttgctaacaaatactggaggtatgatgaatataaacgatct
atggatccaggttatcccaaaatgatagcacatgactttcctggaattggccacaaagtt
gatgcagttttcatgaaagatggatttttctatttctttcatggaacaagacaatacaaa
tttgatcctaaaacgaagagaattttgactctccagaaagctaatagctggttcaactgc
aggaaaaattga

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (19)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (3)   
   RefSeq(pep) (2)   
DNA sequence (48)   
   RefSeq(nuc) (2)   
   GenBank (23)   
   EMBL (23)   
3D Structure (15)   
   PDB (15)   
Protein domain (10)   
   Pfam (10)   
All databases (118)   

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