KEGG   Homo sapiens (human): 4312Help
Entry
4312              CDS       T01001                                 

Gene name
MMP1, CLG, CLGN
Definition
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)
Orthology
K01388  
matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
Organism
hsa  Homo sapiens (human)
Pathway
PPAR signaling pathway
Pathways in cancer
Bladder cancer
Rheumatoid arthritis
Disease
H00028  
Choriocarcinoma
Drug target
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Organismal Systems
  Endocrine system
   03320 PPAR signaling pathway
    4312 (MMP1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    4312 (MMP1)
   05219 Bladder cancer
    4312 (MMP1)
  Immune diseases
   05323 Rheumatoid arthritis
    4312 (MMP1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.7  interstitial collagenase
     4312 (MMP1)
Peptidases [BR:hsa01002]
 Metallo Peptidases
  Family M10
   4312 (MMP1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
11q22.3
AA seq 403 aa AA seqDB search
MQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLP
RADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQ
PGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDV
QLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDRFYMRTN
PFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYS
SFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKV
DAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
NT seq 1212 nt NT seq  +upstreamnt  +downstreamnt
atgcaggaattctttgggctgaaagtgactgggaaaccagatgctgaaaccctgaaggtg
atgaagcagcccagatgtggagtgcctgatgtggctcagtttgtcctcactgaggggaac
cctcgctgggagcaaacacatctgacctacaggattgaaaattacacgccagatttgcca
agagcagatgtggaccatgccattgagaaagccttccaactctggagtaatgtcacacct
ctgacattcaccaaggtctctgagggtcaagcagacatcatgatatcttttgtcagggga
gatcatcgggacaactctccttttgatggacctggaggaaatcttgctcatgcttttcaa
ccaggcccaggtattggaggggatgctcattttgatgaagatgaaaggtggaccaacaat
ttcagagagtacaacttacatcgtgttgcagctcatgaactcggccattctcttggactc
tcccattctactgatatcggggctttgatgtaccctagctacaccttcagtggtgatgtt
cagctagctcaggatgacattgatggcatccaagccatatatggacgttcccaaaatcct
gtccagcccatcggcccacaaaccccaaaagcgtgtgacagtaagctaacctttgatgct
ataactacgattcggggagaagtgatgttctttaaagacagattctacatgcgcacaaat
cccttctacccggaagttgagctcaatttcatttctgttttctggccacaactgccaaat
gggcttgaagctgcttacgaatttgccgacagagatgaagtccggtttttcaaagggaat
aagtactgggctgttcagggacagaatgtgctacacggataccccaaggacatctacagc
tcctttggcttccctagaactgtgaagcatatcgatgctgctctttctgaggaaaacact
ggaaaaacctacttctttgttgctaacaaatactggaggtatgatgaatataaacgatct
atggatccaggttatcccaaaatgatagcacatgactttcctggaattggccacaaagtt
gatgcagttttcatgaaagatggatttttctatttctttcatggaacaagacaatacaaa
tttgatcctaaaacgaagagaattttgactctccagaaagctaatagctggttcaactgc
aggaaaaattga

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