KEGG   Homo sapiens (human): 4360Help
Entry
4360              CDS       T01001                                 

Gene name
MRC1, CD206, CLEC13D, CLEC13DL, MMR, MRC1L1, bA541I19.1, hMR
Definition
(RefSeq) mannose receptor C-type 1
  KO
K06560  mannose receptor, C type
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa05152  Tuberculosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    4360 (MRC1)
 Human Diseases
  Infectious diseases
   05152 Tuberculosis
    4360 (MRC1)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Phagocytosis
   C-lectin receptors
    4360 (MRC1)
Pattern recognition receptors [BR:hsa04054]
 Membrane-bound pattern recognition receptors
  C-type lectin receptors
   4360 (MRC1)
CD molecules [BR:hsa04090]
 Proteins
  4360 (MRC1)
Lectins [BR:hsa04091]
 C-Type lectins
  Group 6: Mannose receptor family
   4360 (MRC1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Lectin_C fn2 Ricin_B_lectin UL45 Xlink CDtoxinA
Motif
Other DBs
NCBI-GeneID: 4360
NCBI-ProteinID: NP_002429
OMIM: 153618
HGNC: 7228
Ensembl: ENSG00000260314
Vega: OTTHUMG00000174646
Pharos: P22897(Tbio)
UniProt: P22897
Structure
PDB: 

Jmol
Position
10p12.33
AA seq 1456 aa AA seqDB search
MRLPLLLVFASVIPGAVLLLDTRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRW
VSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYG
NRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYA
DCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTW
HQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRY
LNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNTTLNSFVIPSESDVPT
HCPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPND
ELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEW
PLGYICKMKSRSQGPEIVEVEKGCRKGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLT
TIEDRYEQAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNSDMPGRKPGC
VAMRTGIAGGLWDVLKCDEKAKFVCKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCF
KLYAKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYG
SPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQ
KGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQS
ESEKKFLWKYVNRNDAQSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCV
TMYSNSGFWNDINCGYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIF
GFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTF
LWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQ
TRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNA
FAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGYWK
TAHCNESFYFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRNWGQAS
LECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRNVEGTWLWINNSPVSFVNW
NTGDPSGERNDCVALHASSGFWSNIHCSSYKGYICKRPKIIDAKPTHELLTTKADTRKMD
PSKPSSNVAGVVIIVILLILTGAGLAAYFFYKKRRVHLPQEGAFENTLYFNSQSSPGTSD
MKDLVGNIEQNEHSVI
NT seq 4371 nt NT seq  +upstreamnt  +downstreamnt
atgaggctacccctgctcctggtttttgcctctgtcattccgggtgctgttctcctactg
gacaccaggcaatttttaatctataatgaagatcacaagcgctgcgtggatgcagtgagt
cccagtgccgtccaaaccgcagcttgcaaccaggatgccgaatcacagaaattccgatgg
gtgtccgaatctcagattatgagtgttgcatttaaattatgcctgggagtgccatcaaaa
acggactgggttgctatcactctctatgcctgtgactcaaaaagtgaatttcagaaatgg
gagtgcaaaaatgacacacttttggggatcaaaggagaagatttattttttaactacggc
aacagacaagaaaagaatattatgctctacaagggatcgggtttatggagcaggtggaag
atctatggaaccacagacaatctgtgctccagaggttatgaagccatgtatacgctacta
ggcaatgccaatggagcaacctgtgcattcccgttcaagtttgaaaacaagtggtacgca
gattgcacgagtgctgggcggtcggatggatggctctggtgcggaaccactactgactat
gacacagacaagctatttggatattgtccattgaaatttgagggcagtgaaagcttatgg
aataaagacccgctgaccagcgtttcctaccagataaactccaaatccgctttaacgtgg
caccaggcgaggaaaagctgccaacaacagaacgctgagctcctgagcatcacagagatt
catgagcaaacatacctgacaggattaaccagttccttgacctcaggactctggattgga
cttaacagtctgagcttcaacagcggttggcagtggagtgaccgcagtcctttccgatat
ttgaactggttaccaggaagtccatcagctgaacctggaaaaagctgtgtgtcactaaat
cctggaaaaaatgctaaatgggaaaatctggaatgtgttcagaaactgggctatatttgc
aaaaagggcaacaccactttaaattcttttgttattccctcagaaagtgatgtgcctact
cactgtcctagtcagtggtggccgtatgccggtcactgttacaagattcacagagatgag
aaaaaaatccagagggatgctctgaccacctgcaggaaggaaggcggtgacctcacaagt
atccacaccatcgaggaattggactttattatctcccagctaggatatgagccaaatgac
gaattgtggatcggcttaaatgacattaagattcaaatgtactttgagtggagtgatggg
acccctgtaacgtttaccaaatggcttcgtggagaaccaagccatgaaaacaacagacag
gaggattgtgtggtgatgaaaggcaaggatgggtactgggcagatcggggctgtgagtgg
cctcttggctacatctgcaagatgaaatcacgaagccaaggtccagaaatagtggaagtc
gaaaaaggctgcaggaaaggctggaaaaaacatcacttttactgctatatgattggacat
acgctttcaacatttgcagaagcaaaccaaacctgtaataatgagaatgcttatttaaca
actattgaagacagatatgaacaagccttcctgactagtttcgttggcttaaggcctgaa
aaatatttctggacaggactttcagatatacaaaccaaagggacttttcagtggaccatc
gaggaagaggttcggttcacccactggaattcagatatgccagggcgaaagccagggtgt
gttgccatgagaaccgggattgcagggggcttatgggatgttttgaaatgtgatgaaaag
gcaaaatttgtgtgcaagcactgggcagaaggagtaacccacccaccgaagcccacgacg
actcccgaacccaaatgtccggaggattggggcgccagcagtagaacaagcttgtgtttc
aagctgtatgcaaaaggaaaacatgagaagaaaacgtggtttgaatctcgagatttttgt
cgagctctgggtggagacttagctagcatcaataacaaagaggaacagcaaacaatatgg
cgattaataacagctagtggaagctaccacaaactgttttggttgggattgacatatgga
agcccttcagaaggttttacttggagtgatggttctcctgtttcatatgaaaactgggct
tatggagaacctaataattatcaaaatgttgaatactgtggtgagctgaaaggtgaccct
actatgtcttggaatgatattaattgtgaacaccttaacaactggatttgccagatacaa
aaaggacaaacaccaaaacctgagccaacaccagctcctcaagacaatccaccagttact
gaagatgggtgggttatttacaaagactaccagtattatttcagcaaagagaaggaaacc
atggacaatgcgcgagcgttttgcaagaggaattttggtgatcttgtttctattcaaagt
gaaagtgaaaagaagtttctatggaaatatgtaaacagaaatgatgcacagtctgcatat
tttattggtttattgatcagcttggataaaaagtttgcttggatggatggaagcaaagtg
gattacgtgtcttgggccacaggtgaacccaattttgcaaatgaagatgaaaactgtgtg
accatgtattcaaattcagggttttggaatgacattaactgtggctatccaaacgccttc
atttgccagcgacataacagtagtatcaatgctaccacagttatgcctaccatgccctcg
gtcccatcagggtgcaaggaaggttggaatttctacagcaacaagtgtttcaaaatcttt
ggatttatggaagaagaaagaaaaaattggcaagaggcacgaaaagcttgtataggcttt
ggagggaatctggtctccatacaaaatgaaaaagagcaagcatttcttacctatcacatg
aaggactccactttcagtgcctggactgggctgaatgatgtcaattcagaacacacgttc
ctttggacggatggacgaggagtccattacacaaactgggggaaaggttaccctggtgga
agaagaagcagtctttcttatgaagatgctgactgtgttgttattattggaggtgcatca
aatgaagcaggaaaatggatggatgatacctgcgacagtaaacgaggctacatatgccag
acacgatccgacccttccttgactaatcctccagcaacgattcaaacagatggctttgtt
aaatatggcaaaagcagctattcactcatgagacaaaaatttcaatggcatgaagcggag
acatactgcaagcttcacaattcccttatagccagcattctggatccctacagtaatgca
tttgcgtggctgcagatggaaacatctaatgaacgtgtgtggatcgccctgaacagtaac
ttgactgataatcaatacacttggactgataagtggagggtgaggtacactaactgggct
gctgatgagcccaaattgaaatcagcatgtgtttatctggatcttgatggctactggaag
acagcacattgcaatgaaagtttttactttctctgtaaaagatcagatgaaatccctgct
actgaacccccacaactgcctggcagatgcccggagtcagatcacacagcatggattcct
ttccatggtcactgttactatattgagtcctcatatacaagaaactggggccaagcttct
ctggaatgtcttcgaatgggttcctctctggtttccattgaaagtgctgcagaatccagt
tttctgtcatatcgggttgagccacttaaaagtaaaaccaatttttggataggattgttc
agaaatgttgaagggacgtggctgtggataaataacagtccggtctcctttgtcaactgg
aacacaggagatccctctggtgaacggaatgattgtgtagctttacatgcgtcttctggg
ttttggagtaatattcactgttcatcctacaaaggatatatttgtaaaagaccaaaaatt
attgatgctaaacctactcatgaattacttacaacaaaagctgacacaaggaagatggac
ccttctaaaccgtcttccaacgtggccggagtagtcatcattgtgatcctcctgatttta
acgggtgctggccttgccgcctatttcttttataagaaaagacgtgtgcacctacctcaa
gagggcgcctttgaaaacactctgtattttaacagtcagtcaagcccaggaactagtgat
atgaaagatctcgtgggcaatattgaacagaatgaacactcggtcatctag

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