KEGG T01001: 4629

Homo sapiens (human): 4629

Entry

4629 CDS T01001

Gene name

MYH11, AAT4, FAA4, SMHC, SMMHC

Definition

myosin, heavy chain 11, smooth muscle

Orthology

K10352

myosin heavy chain

Organism

hsa Homo sapiens (human)

Pathway

hsa04270	Vascular smooth muscle contraction
hsa04530	Tight junction
hsa05416	Viral myocarditis

Disease

H00801

Familial thoracic aortic aneurysm and dissection (TAAD)

Class

Cellular Processes; Cell communication; Tight junction [PATH:hsa04530]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:hsa04270]
Human Diseases; Cardiovascular diseases; Viral myocarditis [PATH:hsa05416]

SSDB

Motif

Pfam:

Myosin_head Myosin_tail_1 Myosin_N Reo_sigmaC IQ Filament ADIP

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

16p13.11

AA seq 1945 aa
MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV
ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL
FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES
GAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKT
VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE
KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV
LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT
KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ
LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA
LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT
KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV
GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ
GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG
VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ
WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ
EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML
DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT
NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD
LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA
RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ
VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK
KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL
SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL
SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV
VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE
EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED
ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA
LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA
TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR
LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ
NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE
ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES
NEAMGREVNALKSKLRGPPPQETSQ

NT seq 5838 nt +upstreamnt +downstreamnt
atggcgcagaagggccaactcagtgacgatgagaagttcctctttgtggacaaaaacttc
atcaacagcccagtggcccaggctgactgggccgccaagagactcgtctgggtcccctcg
gagaagcagggcttcgaggcagccagcattaaggaggagaagggggatgaggtggttgtg
gagctggtggagaatggcaagaaggtcacggttgggaaagatgacatccagaagatgaac
ccacccaagttctccaaggtggaggacatggcggagctgacgtgcctcaacgaagcctcc
gtgctacacaacctgagggagcggtacttctcagggctaatatatacgtactctggcctc
ttctgcgtggtggtcaacccctataaacacctgcccatctactcggagaagatcgtcgac
atgtacaagggcaagaagaggcacgagatgccgcctcacatctacgccatcgcagacacg
gcctaccggagcatgcttcaagatcgggaggaccagtccattctatgcacaggcgagtct
ggagccgggaaaaccgaaaacaccaagaaggtcattcagtacctggccgtggtggcctcc
tcccacaagggcaagaaagacacaagtatcacgcaaggcccatcttttgcctacggagag
ctggaaaagcagcttctacaagcaaacccgattctggaggctttcggcaacgccaaaaca
gtgaagaacgacaactcctcacgattcggcaaattcatccgcatcaacttcgacgtcacg
ggttacatcgtgggagccaacattgagacctatctgctagaaaaatcacgggcaattcgc
caagccagagacgagaggacattccacatcttttactacatgattgctggagccaaggag
aagatgagaagtgacttgcttttggagggcttcaacaactacaccttcctctccaatggc
tttgtgcccatcccagcagcccaggatgatgagatgttccaggaaaccgtggaggccatg
gcaatcatgggtttcagcgaggaggagcagctatccatattgaaggtggtatcatcggtc
ctgcagcttggaaatatcgtcttcaagaaggaaagaaacacagaccaggcgtccatgcca
gataacacagctgctcagaaagtttgccacctcatgggaattaatgtgacagatttcacc
agatccatcctcactcctcgtatcaaggttgggcgagatgtggtacagaaagctcagaca
aaagaacaggctgactttgctgtagaggctttggccaaggcaacatatgagcgccttttc
cgctggatactcacccgcgtgaacaaagccctggacaagacccatcggcaaggggcttcc
ttcctggggatcctggatatagctggatttgagatctttgaggtgaactccttcgagcag
ctgtgcatcaactacaccaacgagaagctgcagcagctcttcaaccacaccatgttcatc
ctggagcaggaggagtaccagcgcgagggcatcgagtggaacttcatcgactttgggctg
gacctacagccctgcatcgagctcatcgagcgaccgaacaaccctccaggtgtgctggcc
ctgctggacgaggaatgctggttccccaaagccacggacaagtctttcgtggagaagctg
tgcacggagcagggcagccaccccaagttccagaagcccaagcagctcaaggacaagact
gagttctccatcatccattatgctgggaaggtggactataatgcgagtgcctggctgacc
aagaatatggacccgctgaatgacaacgtgacttccctgctcaatgcctcctccgacaag
tttgtggccgacctgtggaaggacgtggaccgcatcgtgggcctggaccagatggccaag
atgacggagagctcgctgcccagcgcctccaagaccaagaagggcatgttccgcacagtg
gggcagctgtacaaggagcagctgggcaagctgatgaccacgctacgcaacaccacgccc
aacttcgtgcgctgcatcatccccaaccacgagaagaggtccggcaagctggatgcgttc
ctggtgctggagcagctgcggtgcaatggggtgctggaaggcattcgcatctgccggcag
ggcttccccaaccggatcgtcttccaggagttccgccaacgctacgagatcctggcggcg
aatgccatccccaaaggcttcatggacgggaagcaggcctgcattctcatgatcaaagcc
ctggaacttgaccccaacttatacaggatagggcagagcaaaatcttcttccgaactggc
gtcctggcccacctagaggaggagcgagatttgaagatcaccgatgtcatcatggccttc
caggcgatgtgtcgtggctacttggccagaaaggcttttgccaagaggcagcagcagctg
accgccatgaaggtgattcagaggaactgcgccgcctacctcaagctgcggaactggcag
tggtggaggcttttcaccaaagtgaagccactgctgcaggtgacacggcaggaggaggag
atgcaggccaaggaggatgaactgcagaagaccaaggagcggcagcagaaggcagagaat
gagcttaaggagctggaacagaagcactcgcagctgaccgaggagaagaacctgctacag
gaacagctgcaggcagagacagagctgtatgcagaggctgaggagatgcgggtgcggctg
gcggccaagaagcaggagctggaggagatactgcatgagatggaggcccgcctggaggag
gaggaagacaggggccagcagctacaggctgaaaggaagaagatggcccagcagatgctg
gaccttgaagaacagctggaggaggaggaagctgccaggcagaagctgcaacttgagaag
gtcacggctgaggccaagatcaagaaactggaggatgagatcctggtcatggatgatcag
aacaataaactatcaaaagaacgaaaactccttgaggagaggattagtgacttaacgaca
aatcttgcagaagaggaagaaaaggccaagaatcttaccaagctgaaaaacaagcatgaa
tctatgatttcagaactggaagtgcggctaaagaaggaagagaagagccgacaggagctg
gagaagctgaaacggaagctggagggtgatgccagcgacttccacgagcagatcgctgac
ctccaggcgcagatcgcagagctcaagatgcagctggccaagaaggaggaggagctgcag
gcggccctggccaggcttgacgatgaaatcgctcagaagaacaatgccctgaagaagatc
cgggagctggagggccacatctcagacctccaggaggacctggactcagagcgggccgcc
aggaacaaggctgaaaagcagaagcgagacctcggcgaggagctggaggccctaaagaca
gagctggaagacacactggacagcacagccactcagcaggagctcagggccaagagggag
caggaggtgacggtgctgaagaaggccctggatgaagagacgcggtcccatgaggctcag
gtccaggagatgaggcagaaacacgcacaggcggtggaggagctcacagagcagcttgag
cagttcaagagggccaaggcgaacctagacaagaataagcagacgctggagaaagagaac
gcagacctggccggggagctgcgggtcctgggccaggccaagcaggaggtggaacataag
aagaagaagctggaggcgcaggtgcaggagctgcagtccaagtgcagcgatggggagcgg
gcccgggcggagctcaatgacaaagtccacaagctgcagaatgaagttgagagcgtcaca
gggatgcttaacgaggccgaggggaaggccattaagctggccaaggacgtggcgtccctc
agttcccagctccaggacacccaggagctgcttcaagaagaaacccggcagaagctcaac
gtgtctacgaagctgcgccagctggaggaggagcggaacagcctgcaagaccagctggac
gaggagatggaggccaagcagaacctggagcgccacatctccactctcaacatccagctc
tccgactcgaagaagaagctgcaggactttgccagcaccgtggaagctctggaagagggg
aagaagaggttccagaaggagatcgagaacctcacccagcagtacgaggagaaggcggcc
gcttatgataaactggaaaagaccaagaacaggcttcagcaggagctggacgacctggtt
gttgatttggacaaccagcggcaactcgtgtccaacctggaaaagaagcagaggaaattt
gatcagttgttagccgaggagaaaaacatctcttccaaatacgcggatgagagggacaga
gctgaggcagaagccagggagaaggaaaccaaggccctgtccctggctcgggcccttgaa
gaggccttggaagccaaagaggaactcgagcggaccaacaaaatgctcaaagccgaaatg
gaagacctggtcagctccaaggatgacgtgggcaagaacgtccatgagctggagaagtcc
aagcgggccctggagacccagatggaggagatgaagacgcagctggaagagctggaggac
gagctgcaagccacggaggacgccaaactgcggctggaagtcaacatgcaggcgctcaag
ggccagttcgaaagggatctccaagcccgggacgagcagaatgaggagaagaggaggcaa
ctgcagagacagcttcacgagtatgagacggaactggaagacgagcgaaagcaacgtgcc
ctggcagctgcagcaaagaagaagctggaaggggacctgaaagacctggagcttcaggcc
gactctgccatcaaggggagggaggaagccatcaagcagctacgcaaactgcaggctcag
atgaaggactttcaaagagagctggaagatgcccgtgcctccagagatgagatctttgcc
acagccaaagagaatgagaagaaagccaagagcttggaagcagacctcatgcagctacaa
gaggacctcgccgccgctgagagggctcgcaaacaagcggacctcgagaaggaggaactg
gcagaggagctggccagtagcctgtcgggaaggaacgcactccaggacgagaagcgccgc
ctggaggcccggatcgcccagctggaggaggagctggaggaggagcagggcaacatggag
gccatgagcgaccgggtccgcaaagccacacagcaggccgagcagctcagcaacgagctg
gccacagagcgcagcacggcccagaagaatgagagtgcccggcagcagctcgagcggcag
aacaaggagctccggagcaagctccacgagatggagggggccgtcaagtccaagttcaag
tccaccatcgcggcgctggaggccaagattgcacagctggaggagcaggtcgagcaggag
gccagagagaaacaggcggccaccaagtcgctgaagcagaaagacaagaagctgaaggaa
atcttgctgcaggtggaggacgagcgcaagatggccgagcagtacaaggagcaggcagag
aaaggcaatgccagggtcaagcagctcaagaggcagctggaggaggcagaggaggagtcc
cagcgcatcaacgccaaccgcaggaagctgcagcgggagctggatgaggccacggagagc
aacgaggccatgggccgcgaggtgaacgcactcaagagcaagctcagagggcccccccca
caggaaacttcgcagtga

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (17)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (2)   
   RefSeq(pep) (4)   
DNA sequence (48)   
   RefSeq(nuc) (4)   
   GenBank (22)   
   EMBL (22)   
Protein domain (7)   
   Pfam (7)   
All databases (95)   

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