KEGG   Homo sapiens (human): 4629Help
Entry
4629              CDS       T01001                                 

Gene name
MYH11, AAT4, FAA4, SMHC, SMMHC
Definition
myosin, heavy chain 11, smooth muscle
Orthology
K10352  
myosin heavy chain
Organism
hsa  Homo sapiens (human)
Pathway
Vascular smooth muscle contraction
Tight junction
Disease
H00801  
Familial thoracic aortic aneurysm and dissection (TAAD)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Cellular Processes
  Cell communication
   04530 Tight junction
    4629 (MYH11)
 Organismal Systems
  Circulatory system
   04270 Vascular smooth muscle contraction
    4629 (MYH11)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   4629 (MYH11)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
16p13.11
AA seq 1945 aa AA seqDB search
MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV
ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL
FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES
GAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKT
VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE
KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV
LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT
KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ
LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA
LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT
KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV
GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ
GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG
VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ
WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ
EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML
DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT
NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD
LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA
RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ
VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK
KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL
SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL
SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV
VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE
EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED
ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA
LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA
TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR
LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ
NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE
ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES
NEAMGREVNALKSKLRGPPPQETSQ
NT seq 5838 nt NT seq  +upstreamnt  +downstreamnt
atggcgcagaagggccaactcagtgacgatgagaagttcctctttgtggacaaaaacttc
atcaacagcccagtggcccaggctgactgggccgccaagagactcgtctgggtcccctcg
gagaagcagggcttcgaggcagccagcattaaggaggagaagggggatgaggtggttgtg
gagctggtggagaatggcaagaaggtcacggttgggaaagatgacatccagaagatgaac
ccacccaagttctccaaggtggaggacatggcggagctgacgtgcctcaacgaagcctcc
gtgctacacaacctgagggagcggtacttctcagggctaatatatacgtactctggcctc
ttctgcgtggtggtcaacccctataaacacctgcccatctactcggagaagatcgtcgac
atgtacaagggcaagaagaggcacgagatgccgcctcacatctacgccatcgcagacacg
gcctaccggagcatgcttcaagatcgggaggaccagtccattctatgcacaggcgagtct
ggagccgggaaaaccgaaaacaccaagaaggtcattcagtacctggccgtggtggcctcc
tcccacaagggcaagaaagacacaagtatcacgcaaggcccatcttttgcctacggagag
ctggaaaagcagcttctacaagcaaacccgattctggaggctttcggcaacgccaaaaca
gtgaagaacgacaactcctcacgattcggcaaattcatccgcatcaacttcgacgtcacg
ggttacatcgtgggagccaacattgagacctatctgctagaaaaatcacgggcaattcgc
caagccagagacgagaggacattccacatcttttactacatgattgctggagccaaggag
aagatgagaagtgacttgcttttggagggcttcaacaactacaccttcctctccaatggc
tttgtgcccatcccagcagcccaggatgatgagatgttccaggaaaccgtggaggccatg
gcaatcatgggtttcagcgaggaggagcagctatccatattgaaggtggtatcatcggtc
ctgcagcttggaaatatcgtcttcaagaaggaaagaaacacagaccaggcgtccatgcca
gataacacagctgctcagaaagtttgccacctcatgggaattaatgtgacagatttcacc
agatccatcctcactcctcgtatcaaggttgggcgagatgtggtacagaaagctcagaca
aaagaacaggctgactttgctgtagaggctttggccaaggcaacatatgagcgccttttc
cgctggatactcacccgcgtgaacaaagccctggacaagacccatcggcaaggggcttcc
ttcctggggatcctggatatagctggatttgagatctttgaggtgaactccttcgagcag
ctgtgcatcaactacaccaacgagaagctgcagcagctcttcaaccacaccatgttcatc
ctggagcaggaggagtaccagcgcgagggcatcgagtggaacttcatcgactttgggctg
gacctacagccctgcatcgagctcatcgagcgaccgaacaaccctccaggtgtgctggcc
ctgctggacgaggaatgctggttccccaaagccacggacaagtctttcgtggagaagctg
tgcacggagcagggcagccaccccaagttccagaagcccaagcagctcaaggacaagact
gagttctccatcatccattatgctgggaaggtggactataatgcgagtgcctggctgacc
aagaatatggacccgctgaatgacaacgtgacttccctgctcaatgcctcctccgacaag
tttgtggccgacctgtggaaggacgtggaccgcatcgtgggcctggaccagatggccaag
atgacggagagctcgctgcccagcgcctccaagaccaagaagggcatgttccgcacagtg
gggcagctgtacaaggagcagctgggcaagctgatgaccacgctacgcaacaccacgccc
aacttcgtgcgctgcatcatccccaaccacgagaagaggtccggcaagctggatgcgttc
ctggtgctggagcagctgcggtgcaatggggtgctggaaggcattcgcatctgccggcag
ggcttccccaaccggatcgtcttccaggagttccgccaacgctacgagatcctggcggcg
aatgccatccccaaaggcttcatggacgggaagcaggcctgcattctcatgatcaaagcc
ctggaacttgaccccaacttatacaggatagggcagagcaaaatcttcttccgaactggc
gtcctggcccacctagaggaggagcgagatttgaagatcaccgatgtcatcatggccttc
caggcgatgtgtcgtggctacttggccagaaaggcttttgccaagaggcagcagcagctg
accgccatgaaggtgattcagaggaactgcgccgcctacctcaagctgcggaactggcag
tggtggaggcttttcaccaaagtgaagccactgctgcaggtgacacggcaggaggaggag
atgcaggccaaggaggatgaactgcagaagaccaaggagcggcagcagaaggcagagaat
gagcttaaggagctggaacagaagcactcgcagctgaccgaggagaagaacctgctacag
gaacagctgcaggcagagacagagctgtatgcagaggctgaggagatgcgggtgcggctg
gcggccaagaagcaggagctggaggagatactgcatgagatggaggcccgcctggaggag
gaggaagacaggggccagcagctacaggctgaaaggaagaagatggcccagcagatgctg
gaccttgaagaacagctggaggaggaggaagctgccaggcagaagctgcaacttgagaag
gtcacggctgaggccaagatcaagaaactggaggatgagatcctggtcatggatgatcag
aacaataaactatcaaaagaacgaaaactccttgaggagaggattagtgacttaacgaca
aatcttgcagaagaggaagaaaaggccaagaatcttaccaagctgaaaaacaagcatgaa
tctatgatttcagaactggaagtgcggctaaagaaggaagagaagagccgacaggagctg
gagaagctgaaacggaagctggagggtgatgccagcgacttccacgagcagatcgctgac
ctccaggcgcagatcgcagagctcaagatgcagctggccaagaaggaggaggagctgcag
gcggccctggccaggcttgacgatgaaatcgctcagaagaacaatgccctgaagaagatc
cgggagctggagggccacatctcagacctccaggaggacctggactcagagcgggccgcc
aggaacaaggctgaaaagcagaagcgagacctcggcgaggagctggaggccctaaagaca
gagctggaagacacactggacagcacagccactcagcaggagctcagggccaagagggag
caggaggtgacggtgctgaagaaggccctggatgaagagacgcggtcccatgaggctcag
gtccaggagatgaggcagaaacacgcacaggcggtggaggagctcacagagcagcttgag
cagttcaagagggccaaggcgaacctagacaagaataagcagacgctggagaaagagaac
gcagacctggccggggagctgcgggtcctgggccaggccaagcaggaggtggaacataag
aagaagaagctggaggcgcaggtgcaggagctgcagtccaagtgcagcgatggggagcgg
gcccgggcggagctcaatgacaaagtccacaagctgcagaatgaagttgagagcgtcaca
gggatgcttaacgaggccgaggggaaggccattaagctggccaaggacgtggcgtccctc
agttcccagctccaggacacccaggagctgcttcaagaagaaacccggcagaagctcaac
gtgtctacgaagctgcgccagctggaggaggagcggaacagcctgcaagaccagctggac
gaggagatggaggccaagcagaacctggagcgccacatctccactctcaacatccagctc
tccgactcgaagaagaagctgcaggactttgccagcaccgtggaagctctggaagagggg
aagaagaggttccagaaggagatcgagaacctcacccagcagtacgaggagaaggcggcc
gcttatgataaactggaaaagaccaagaacaggcttcagcaggagctggacgacctggtt
gttgatttggacaaccagcggcaactcgtgtccaacctggaaaagaagcagaggaaattt
gatcagttgttagccgaggagaaaaacatctcttccaaatacgcggatgagagggacaga
gctgaggcagaagccagggagaaggaaaccaaggccctgtccctggctcgggcccttgaa
gaggccttggaagccaaagaggaactcgagcggaccaacaaaatgctcaaagccgaaatg
gaagacctggtcagctccaaggatgacgtgggcaagaacgtccatgagctggagaagtcc
aagcgggccctggagacccagatggaggagatgaagacgcagctggaagagctggaggac
gagctgcaagccacggaggacgccaaactgcggctggaagtcaacatgcaggcgctcaag
ggccagttcgaaagggatctccaagcccgggacgagcagaatgaggagaagaggaggcaa
ctgcagagacagcttcacgagtatgagacggaactggaagacgagcgaaagcaacgtgcc
ctggcagctgcagcaaagaagaagctggaaggggacctgaaagacctggagcttcaggcc
gactctgccatcaaggggagggaggaagccatcaagcagctacgcaaactgcaggctcag
atgaaggactttcaaagagagctggaagatgcccgtgcctccagagatgagatctttgcc
acagccaaagagaatgagaagaaagccaagagcttggaagcagacctcatgcagctacaa
gaggacctcgccgccgctgagagggctcgcaaacaagcggacctcgagaaggaggaactg
gcagaggagctggccagtagcctgtcgggaaggaacgcactccaggacgagaagcgccgc
ctggaggcccggatcgcccagctggaggaggagctggaggaggagcagggcaacatggag
gccatgagcgaccgggtccgcaaagccacacagcaggccgagcagctcagcaacgagctg
gccacagagcgcagcacggcccagaagaatgagagtgcccggcagcagctcgagcggcag
aacaaggagctccggagcaagctccacgagatggagggggccgtcaagtccaagttcaag
tccaccatcgcggcgctggaggccaagattgcacagctggaggagcaggtcgagcaggag
gccagagagaaacaggcggccaccaagtcgctgaagcagaaagacaagaagctgaaggaa
atcttgctgcaggtggaggacgagcgcaagatggccgagcagtacaaggagcaggcagag
aaaggcaatgccagggtcaagcagctcaagaggcagctggaggaggcagaggaggagtcc
cagcgcatcaacgccaaccgcaggaagctgcagcgggagctggatgaggccacggagagc
aacgaggccatgggccgcgaggtgaacgcactcaagagcaagctcagagggcccccccca
caggaaacttcgcagtga

DBGET integrated database retrieval system