KEGG T01001: 4772

Homo sapiens (human): 4772

Entry

4772 CDS T01001

Gene name

NFATC1, NF-ATC, NFAT2, NFATc

Definition

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

Orthology

K04446

nuclear factor of activated T-cells, cytoplasmic

Organism

hsa Homo sapiens (human)

Pathway

hsa04310	Wnt signaling pathway
hsa04360	Axon guidance
hsa04370	VEGF signaling pathway
hsa04380	Osteoclast differentiation
hsa04650	Natural killer cell mediated cytotoxicity
hsa04660	T cell receptor signaling pathway
hsa04662	B cell receptor signaling pathway
hsa05161	Hepatitis B
hsa05166	HTLV-I infection

Class

Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:hsa04310]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:hsa04370]
Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:hsa04650]
Organismal Systems; Immune system; T cell receptor signaling pathway [PATH:hsa04660]
Organismal Systems; Immune system; B cell receptor signaling pathway [PATH:hsa04662]
Organismal Systems; Development; Axon guidance [PATH:hsa04360]
Organismal Systems; Development; Osteoclast differentiation [PATH:hsa04380]
Human Diseases; Infectious diseases; HTLV-I infection [PATH:hsa05166]
Human Diseases; Infectious diseases; Hepatitis B [PATH:hsa05161]

SSDB

Motif

Pfam:

RHD TIG

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

O95644 B5B2M5 B5B2M8 B5B2M9 Q2M1S3

Structure

PDB:

1A66 1NFA

Position

18q23

AA seq 825 aa
MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQ
GLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGV
ASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQ

NT seq 2478 nt +upstreamnt +downstreamnt
atgccaagcaccagctttccagtcccttccaagtttccacttggccctgcggctgcggtc
ttcgggagaggagaaactttggggcccgcgccgcgcgccggcggcaccatgaagtcagcg
gaggaagaacactatggctatgcatcctccaacgtcagccccgccctgccgctccccacg
gcgcactccaccctgccggccccgtgccacaaccttcagacctccacaccgggcatcatc
ccgccggcggatcacccctcggggtacggagcagctttggacggtgggcccgcgggctac
ttcctctcctccggccacaccaggcctgatggggcccctgccctggagagtcctcgcatc
gagataacctcgtgcttgggcctgtaccacaacaataaccagtttttccacgatgtggag
gtggaagacgtcctccctagctccaaacggtccccctccacggccacgctgagtctgccc
agcctggaggcctacagagacccctcgtgcctgagcccggccagcagcctgtcctcccgg
agctgcaactcagaggcctcctcctacgagtccaactactcgtacccgtacgcgtccccc
cagacgtcgccatggcagtctccctgcgtgtctcccaagaccacggaccccgaggagggc
tttccccgcgggctgggggcctgcacactgctgggttccccgcggcactccccctccacc
tcgccccgcgccagcgtcactgaggagagctggctgggtgcccgctcctccagacccgcg
tccccttgcaacaagaggaagtacagcctcaacggccggcagccgccctactcaccccac
cactcgcccacgccgtccccgcacggctccccgcgggtcagcgtgaccgacgactcgtgg
ttgggcaacaccacccagtacaccagctcggccatcgtggccgccatcaacgcgctgacc
accgacagcagcctggacctgggagatggcgtccctgtcaagtcccgcaagaccaccctg
gagcagccgccctcagtggcgctcaaggtggagcccgtcggggaggacctgggcagcccc
ccgcccccggccgacttcgcgcccgaagactactcctctttccagcacatcaggaagggc
ggcttctgcgaccagtacctggcggtgccgcagcacccctaccagtgggcgaagcccaag
cccctgtcccctacgtcctacatgagcccgaccctgcccgccctggactggcagctgccg
tcccactcaggcccgtatgagcttcggattgaggtgcagcccaagtcccaccaccgagcc
cactacgagacggagggcagccggggggccgtgaaggcgtcggccggaggacaccccatc
gtgcagctgcatggctacttggagaatgagccgctgatgctgcagcttttcattgggacg
gcggacgaccgcctgctgcgcccgcacgccttctaccaggtgcaccgcatcacagggaag
accgtgtccaccaccagccacgaggccatcctctccaacaccaaagtcctggagatccca
ctcctgccggagaacagcatgcgagccgtcattgactgtgccggaatcctgaaactcaga
aactccgacattgaacttcggaaaggagagacggacatcgggaggaagaacacacgggta
cggctggtgttccgcgttcacgtcccgcaacccagcggccgcacgctgtccctgcaggtg
gcctccaaccccatcgaatgctcccagcgctcagctcaggagctgcctctggtggagaag
cagagcacggacagctatccggtcgtgggcgggaagaagatggtcctgtctggccacaac
ttcctgcaggactccaaggtcattttcgtggagaaagccccagatggccaccatgtctgg
gagatggaagcgaaaactgaccgggacctgtgcaagccgaattctctggtggttgagatc
ccgccatttcggaatcagaggataaccagccccgttcacgtcagtttctacgtctgcaac
gggaagagaaagcgaagccagtaccagcgtttcacctaccttcccgccaacgttccaatt
ataaaaacagaacccactgatgattatgagcctgctccaacctgtggaccggtgagccag
gggttaagtcctctcccaagaccatactacagccagcagctcgcgatgccacccgacccc
agctcctgcctcgtggccggcttcccgccctgtccgcagagaagcaccctgatgccagcg
gcccctggcgtgagccccaagctccacgacctttctcccgctgcctacaccaagggcgtt
gccagcccgggccactgtcacctcggactcccgcagccggccggagaggcccccgccgtc
caggacgtgcccaggccagtggccacgcaccccggctcgcccgggcagccacccccggcc
ctgctgccacagcagtaa

All links

Pathway (9)   
   KEGG PATHWAY (9)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (18)   
   UniGene (2)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (10)   
   UniProt (5)   
   RefSeq(pep) (5)   
DNA sequence (49)   
   RefSeq(nuc) (5)   
   GenBank (22)   
   EMBL (22)   
3D Structure (2)   
   PDB (2)   
Protein domain (2)   
   Pfam (2)   
All databases (101)   

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