KEGG   Homo sapiens (human): 483Help
Entry
483               CDS       T01001                                 

Gene name
ATP1B3, ATPB-3, CD298
Definition
ATPase, Na+/K+ transporting, beta 3 polypeptide (EC:3.6.3.9)
Orthology
K01540  
sodium/potassium-transporting ATPase subunit beta
Organism
hsa  Homo sapiens (human)
Pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Insulin secretion
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Aldosterone-regulated sodium reabsorption
Endocrine and other factor-regulated calcium reabsorption
Proximal tubule bicarbonate reclamation
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Carbohydrate digestion and absorption
Protein digestion and absorption
Bile secretion
Mineral absorption
Drug target
Acetyldigitoxin: 
Acetyldigoxin: 
Digitoxin: 
Digoxin: 
Lanatoside C: 
Deslanoside: 
Metildigoxin: 
Gitoformate: 
Proscillaridin: 
G-strophanthin: 
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04024 cAMP signaling pathway
    483 (ATP1B3)
   04022 cGMP - PKG signaling pathway
    483 (ATP1B3)
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    483 (ATP1B3)
   04918 Thyroid hormone synthesis
    483 (ATP1B3)
   04919 Thyroid hormone signaling pathway
    483 (ATP1B3)
  Circulatory system
   04260 Cardiac muscle contraction
    483 (ATP1B3)
   04261 Adrenergic signaling in cardiomyocytes
    483 (ATP1B3)
  Digestive system
   04970 Salivary secretion
    483 (ATP1B3)
   04971 Gastric acid secretion
    483 (ATP1B3)
   04972 Pancreatic secretion
    483 (ATP1B3)
   04976 Bile secretion
    483 (ATP1B3)
   04973 Carbohydrate digestion and absorption
    483 (ATP1B3)
   04974 Protein digestion and absorption
    483 (ATP1B3)
   04978 Mineral absorption
    483 (ATP1B3)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    483 (ATP1B3)
   04961 Endocrine and other factor-regulated calcium reabsorption
    483 (ATP1B3)
   04964 Proximal tubule bicarbonate reclamation
    483 (ATP1B3)
Cellular antigens [BR:hsa04090]
 Proteins
  483 (ATP1B3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
3q23
AA seq 279 aa AA seqDB search
MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWV
MLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLE
EQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIG
LKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPN
NTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA
NT seq 840 nt NT seq  +upstreamnt  +downstreamnt
atgacgaagaacgagaagaagtccctcaaccagagcctggccgagtggaagctcttcatc
tacaacccgaccaccggagaattcctggggcgcaccgccaagagctggggtttgatcttg
ctcttctacctagttttttatgggttcctggctgcactcttctcattcacgatgtgggtt
atgcttcagactctcaacgatgaggttccaaaataccgtgaccagattcctagcccagga
ctcatggtttttccaaaaccagtgaccgcattggaatatacattcagtaggtctgatcca
acttcgtatgcagggtacattgaagaccttaagaagtttctaaaaccatatactttagaa
gaacagaagaacctcacagtctgtcctgatggagcactttttgaacagaagggtccagtt
tatgttgcatgtcagtttcctatttcattacttcaagcatgcagtggtatgaatgatcct
gattttggctattctcaaggaaacccttgtattcttgtgaaaatgaacagaataattgga
ttaaagcctgaaggagtgccaaggatagattgtgtttcaaagaatgaagatataccaaat
gtagcagtttatcctcataatggaatgatagacttaaaatatttcccatattatgggaaa
aaactgcatgttgggtatctacagccattggttgctgttcaggtcagctttgctcctaac
aacactgggaaagaagtaacagttgagtgcaagattgatggatcagccaacctaaaaagt
caggatgatcgtgacaagtttttgggacgagttatgttcaaaatcacagcacgtgcatag

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