KEGG T01001: 491

Homo sapiens (human): 491

Entry

491 CDS T01001

Gene name

ATP2B2, PMCA2, PMCA2a, PMCA2i

Definition

ATPase, Ca++ transporting, plasma membrane 2 (EC:3.6.3.8)

Orthology

K05850

Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]

Organism

hsa Homo sapiens (human)

Pathway

hsa04020	Calcium signaling pathway
hsa04970	Salivary secretion
hsa04972	Pancreatic secretion

Class

Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:hsa04020]
Organismal Systems; Digestive system; Salivary secretion [PATH:hsa04970]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:hsa04972]

SSDB

Motif

Pfam:

E1-E2_ATPase Cation_ATPase_C ATP_Ca_trans_C Hydrolase Hydrolase_like2 HAD Cation_ATPase_N Hydrolase_3 DUF106

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

3p25.3

AA seq 1243 aa
MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL
KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG
LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR
GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS
LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD
KKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ
PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT
FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL
VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN
AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY
TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV
IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC
QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK
IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA
GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT
QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV
YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER
NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV
IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ
IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS
SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL

NT seq 3732 nt +upstreamnt +downstreamnt
atgggtgacatgaccaacagcgacttttactccaaaaaccaaagaaatgagtcgagccat
gggggcgagttcgggtgcacaatggaggagctccgctccctcatggagctgcggggcact
gaggctgtggtcaagatcaaggagacttatggggacaccgaagccatctgccggcgcctc
aaaacctcacctgttgaaggtttgccgggcaccgctccagacctggaaaagagaaagcaa
atttttgggcaaaactttatacctccaaagaagccaaaaaccttcctgcagctcgtgtgg
gaggcgctgcaggacgtgacgctcatcatcctggagattgccgccatcatctccctgggg
ctgtccttctaccacccgcccggcgagggcaacgaaggatgtgcgacggcccagggtggg
gcagaggatgaaggagaggcagaggcaggttggatcgagggggccgccattctcctctca
gttatctgtgtggtcctggtcacggccttcaatgactggagcaaagagaaacagttccgg
ggcctgcagagccgcatcgagcaggaacagaaatttaccgtggtccgggctggccaggtg
gtccagatccctgtggctgagatcgtggttggggacatagcccaggtcaaatatggtgac
ctcctccctgccgacggcctcttcatccagggcaatgacctcaagattgatgaaagctcc
ctaactggagagtctgaccaggtgcgcaagtccgtggacaaggaccccatgctgctgtca
ggaacccacgtgatggagggctcaggacggatgttggtgactgctgtgggtgtgaactct
cagactggcatcatctttaccctcctgggggctggtggtgaagaggaagagaagaaagac
aaaaaaggtgtgaagaagggggatggccttcagctaccagcagcagacggtgcggcagct
tcaaatgctgcagatagtgcgaatgccagcctagtcaatggtaaaatgcaggatggcaat
gtggacgccagccagagcaaagccaaacaacaggacggggcagccgccatggagatgcag
cccctcaagagtgccgagggcggcgacgctgacgacaggaagaaggccagcatgcacaag
aaggagaagtccgtgctgcagggcaagctcaccaagctggctgtgcagatcgggaaggcg
ggcttggtgatgtcagccatcacggtgatcatcctggtgctctacttcactgtggacacc
ttcgtggtcaacaagaagccgtggctgcctgagtgcacgcccgtctacgtgcagtacttt
gtcaagttcttcatcattggcgtgacggtgctggtggtcgccgtgcccgaggggctccct
ctggccgtcaccatctcgttggcctattcggtgaagaaaatgatgaaggacaacaacctg
gtacgccacctggatgcctgtgagaccatgggcaatgccacagccatctgctcagacaag
acaggcacgctgaccaccaatcgcatgacagtggtacaggcctatgtcggcgacgtccac
tataaagagatccccgaccccagctccatcaacaccaagaccatggagctgctgatcaat
gccatcgccatcaacagcgcctacaccaccaagattctgcccccagagaaggagggcgcc
ctgcctcggcaggtgggcaacaagacggagtgcggcctgctgggcttcgtgctggacctg
aagcaggactacgagcccgtgcgcagccagatgccagaggagaagttgtacaaagtgtac
accttcaactccgtgcgcaagtccatgagcactgtcatcaagctgcccgacgagagcttc
cgcatgtacagcaagggggcttctgagatcgtgctcaagaagtgctgcaaaatcctcaat
ggggcgggagagcctcgtgtcttccggccccgcgaccgggacgagatggtaaagaaggtg
attgagcccatggcttgcgatgggctccgcactatctgcgtggcctaccgcgacttcccc
agcagcccggagccggactgggacaatgagaatgacatcctcaacgaactcacctgcatc
tgcgtggtgggcatcgaggacccggtgcggccagaggtcccagaagccatccgcaagtgc
cagcgggcaggcatcacggtccgcatggtcactggcgacaatatcaacacggctcgggcc
atcgccatcaagtgtggcatcatccatcctggggaggactttctgtgcctcgagggcaag
gagttcaacaggaggatccgcaacgagaagggggagattgagcaggagcgaattgacaag
atctggccaaagctgcgggtgctggctcgctcctccccaacggacaagcataccctggtt
aaaggcatcatcgacagcacacacactgagcagcggcaggtggtggccgtgacgggggac
gggaccaacgacgggcctgcactcaagaaggccgacgtgggcttcgccatgggcatcgca
ggcactgacgtggccaaggaggcctcagacatcatcctgacagacgacaatttcagcagc
atcgtcaaggcagtgatgtggggccgcaacgtctatgacagcatctccaaattcttgcag
ttccagctcaccgtcaacgtggtggccgtgattgtggccttcacaggcgcctgcatcacg
caggactcccctctgaaggccgtgcagatgctctgggtgaacctcatcatggacacgttt
gcctcgctggcactggccactgagccgcccacggagaccctgctgctgaggaagccgtac
ggccgcaacaagccgctcatctccaggaccatgatgaagaacatcctgggccatgctgtc
taccagcttgccctcatcttcaccctgctctttgttggcgagaagatgttccagatcgac
agcgggaggaacgcgcccctgcattcgccaccctcagaacattacaccatcatcttcaac
accttcgtcatgatgcagctcttcaacgagatcaacgcccgcaagatccacggcgagcgc
aatgtctttgacggcatcttccggaaccccatcttctgcaccatcgtgctgggcaccttt
gccatccagatagtgatcgtgcagtttggagggaagccattcagctgctctccactgcag
ctggaccagtggatgtggtgcatattcattgggttaggagagctcgtttggggccaggtc
atcgccaccatcccgaccagcagactcaagttcctcaaggaggcaggcaggctcacacag
aaggaggagatcccggaggaggagctcaacgaggacgtggaggagatcgaccacgcggag
cgggagctgcggcggggccagatcctgtggttccgaggcctgaatcggatccagacacag
atccgcgtcgtgaaggcgttccgtagctctctctatgaaggtttagaaaagcctgaatct
cgaacctccatccataacttcatggctcatcctgaattccggatcgaagattcccagccc
cacatccccctcattgatgacaccgacctggaagaagatgccgcgctcaagcagaactcg
agcccgccgtcatccctcaacaagaacaacagcgccatcgacagtgggatcaacctgacg
accgacacaagcaaatcagctacctcttcaagtccagggagccccatccacagcctggag
acgtcgctttag

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (2)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (12)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (3)   
   RefSeq(pep) (2)   
DNA sequence (42)   
   RefSeq(nuc) (2)   
   GenBank (20)   
   EMBL (20)   
Protein domain (9)   
   Pfam (9)   
All databases (83)   

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