KEGG   Homo sapiens (human): 491Help
Entry
491               CDS       T01001                                 

Gene name
ATP2B2, PMCA2, PMCA2a, PMCA2i
Definition
ATPase, Ca++ transporting, plasma membrane 2 (EC:3.6.3.8)
Orthology
K05850  
Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
Organism
hsa  Homo sapiens (human)
Pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Adrenergic signaling in cardiomyocytes
Salivary secretion
Pancreatic secretion
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    491 (ATP2B2)
   04024 cAMP signaling pathway
    491 (ATP2B2)
   04022 cGMP - PKG signaling pathway
    491 (ATP2B2)
 Organismal Systems
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    491 (ATP2B2)
  Digestive system
   04970 Salivary secretion
    491 (ATP2B2)
   04972 Pancreatic secretion
    491 (ATP2B2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.3  Acting on acid anhydrides to catalyse transmembrane movement of substances
    3.6.3.8  Ca2+-transporting ATPase
     491 (ATP2B2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
3p25.3
AA seq 1243 aa AA seqDB search
MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL
KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG
LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR
GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS
LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD
KKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ
PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT
FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL
VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN
AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY
TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV
IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC
QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK
IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA
GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT
QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV
YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER
NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV
IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ
IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS
SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL
NT seq 3732 nt NT seq  +upstreamnt  +downstreamnt
atgggtgacatgaccaacagcgacttttactccaaaaaccaaagaaatgagtcgagccat
gggggcgagttcgggtgcacaatggaggagctccgctccctcatggagctgcggggcact
gaggctgtggtcaagatcaaggagacttatggggacaccgaagccatctgccggcgcctc
aaaacctcacctgttgaaggtttgccgggcaccgctccagacctggaaaagagaaagcaa
atttttgggcaaaactttatacctccaaagaagccaaaaaccttcctgcagctcgtgtgg
gaggcgctgcaggacgtgacgctcatcatcctggagattgccgccatcatctccctgggg
ctgtccttctaccacccgcccggcgagggcaacgaaggatgtgcgacggcccagggtggg
gcagaggatgaaggagaggcagaggcaggttggatcgagggggccgccattctcctctca
gttatctgtgtggtcctggtcacggccttcaatgactggagcaaagagaaacagttccgg
ggcctgcagagccgcatcgagcaggaacagaaatttaccgtggtccgggctggccaggtg
gtccagatccctgtggctgagatcgtggttggggacatagcccaggtcaaatatggtgac
ctcctccctgccgacggcctcttcatccagggcaatgacctcaagattgatgaaagctcc
ctaactggagagtctgaccaggtgcgcaagtccgtggacaaggaccccatgctgctgtca
ggaacccacgtgatggagggctcaggacggatgttggtgactgctgtgggtgtgaactct
cagactggcatcatctttaccctcctgggggctggtggtgaagaggaagagaagaaagac
aaaaaaggtgtgaagaagggggatggccttcagctaccagcagcagacggtgcggcagct
tcaaatgctgcagatagtgcgaatgccagcctagtcaatggtaaaatgcaggatggcaat
gtggacgccagccagagcaaagccaaacaacaggacggggcagccgccatggagatgcag
cccctcaagagtgccgagggcggcgacgctgacgacaggaagaaggccagcatgcacaag
aaggagaagtccgtgctgcagggcaagctcaccaagctggctgtgcagatcgggaaggcg
ggcttggtgatgtcagccatcacggtgatcatcctggtgctctacttcactgtggacacc
ttcgtggtcaacaagaagccgtggctgcctgagtgcacgcccgtctacgtgcagtacttt
gtcaagttcttcatcattggcgtgacggtgctggtggtcgccgtgcccgaggggctccct
ctggccgtcaccatctcgttggcctattcggtgaagaaaatgatgaaggacaacaacctg
gtacgccacctggatgcctgtgagaccatgggcaatgccacagccatctgctcagacaag
acaggcacgctgaccaccaatcgcatgacagtggtacaggcctatgtcggcgacgtccac
tataaagagatccccgaccccagctccatcaacaccaagaccatggagctgctgatcaat
gccatcgccatcaacagcgcctacaccaccaagattctgcccccagagaaggagggcgcc
ctgcctcggcaggtgggcaacaagacggagtgcggcctgctgggcttcgtgctggacctg
aagcaggactacgagcccgtgcgcagccagatgccagaggagaagttgtacaaagtgtac
accttcaactccgtgcgcaagtccatgagcactgtcatcaagctgcccgacgagagcttc
cgcatgtacagcaagggggcttctgagatcgtgctcaagaagtgctgcaaaatcctcaat
ggggcgggagagcctcgtgtcttccggccccgcgaccgggacgagatggtaaagaaggtg
attgagcccatggcttgcgatgggctccgcactatctgcgtggcctaccgcgacttcccc
agcagcccggagccggactgggacaatgagaatgacatcctcaacgaactcacctgcatc
tgcgtggtgggcatcgaggacccggtgcggccagaggtcccagaagccatccgcaagtgc
cagcgggcaggcatcacggtccgcatggtcactggcgacaatatcaacacggctcgggcc
atcgccatcaagtgtggcatcatccatcctggggaggactttctgtgcctcgagggcaag
gagttcaacaggaggatccgcaacgagaagggggagattgagcaggagcgaattgacaag
atctggccaaagctgcgggtgctggctcgctcctccccaacggacaagcataccctggtt
aaaggcatcatcgacagcacacacactgagcagcggcaggtggtggccgtgacgggggac
gggaccaacgacgggcctgcactcaagaaggccgacgtgggcttcgccatgggcatcgca
ggcactgacgtggccaaggaggcctcagacatcatcctgacagacgacaatttcagcagc
atcgtcaaggcagtgatgtggggccgcaacgtctatgacagcatctccaaattcttgcag
ttccagctcaccgtcaacgtggtggccgtgattgtggccttcacaggcgcctgcatcacg
caggactcccctctgaaggccgtgcagatgctctgggtgaacctcatcatggacacgttt
gcctcgctggcactggccactgagccgcccacggagaccctgctgctgaggaagccgtac
ggccgcaacaagccgctcatctccaggaccatgatgaagaacatcctgggccatgctgtc
taccagcttgccctcatcttcaccctgctctttgttggcgagaagatgttccagatcgac
agcgggaggaacgcgcccctgcattcgccaccctcagaacattacaccatcatcttcaac
accttcgtcatgatgcagctcttcaacgagatcaacgcccgcaagatccacggcgagcgc
aatgtctttgacggcatcttccggaaccccatcttctgcaccatcgtgctgggcaccttt
gccatccagatagtgatcgtgcagtttggagggaagccattcagctgctctccactgcag
ctggaccagtggatgtggtgcatattcattgggttaggagagctcgtttggggccaggtc
atcgccaccatcccgaccagcagactcaagttcctcaaggaggcaggcaggctcacacag
aaggaggagatcccggaggaggagctcaacgaggacgtggaggagatcgaccacgcggag
cgggagctgcggcggggccagatcctgtggttccgaggcctgaatcggatccagacacag
atccgcgtcgtgaaggcgttccgtagctctctctatgaaggtttagaaaagcctgaatct
cgaacctccatccataacttcatggctcatcctgaattccggatcgaagattcccagccc
cacatccccctcattgatgacaccgacctggaagaagatgccgcgctcaagcagaactcg
agcccgccgtcatccctcaacaagaacaacagcgccatcgacagtgggatcaacctgacg
accgacacaagcaaatcagctacctcttcaagtccagggagccccatccacagcctggag
acgtcgctttag

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