KEGG   Homo sapiens (human): 491Help
Entry
491               CDS       T01001                                 

Gene name
ATP2B2, PMCA2, PMCA2a, PMCA2i
Definition
(RefSeq) ATPase plasma membrane Ca2+ transporting 2
  KO
K05850  
Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
Organism
hsa  Homo sapiens (human)
Pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Adrenergic signaling in cardiomyocytes
Aldosterone synthesis and secretion
Salivary secretion
Pancreatic secretion
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    491 (ATP2B2)
   04024 cAMP signaling pathway
    491 (ATP2B2)
   04022 cGMP - PKG signaling pathway
    491 (ATP2B2)
 Organismal Systems
  Endocrine system
   04925 Aldosterone synthesis and secretion
    491 (ATP2B2)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    491 (ATP2B2)
  Digestive system
   04970 Salivary secretion
    491 (ATP2B2)
   04972 Pancreatic secretion
    491 (ATP2B2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.3  Acting on acid anhydrides to catalyse transmembrane movement of substances
    3.6.3.8  Ca2+-transporting ATPase
     491 (ATP2B2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
Q01814(Tbio)
UniProt: 
Position
3p25.3
AA seq 1243 aa AA seqDB search
MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL
KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG
LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR
GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS
LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD
KKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ
PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT
FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL
VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN
AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY
TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV
IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC
QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK
IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA
GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT
QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV
YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER
NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV
IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ
IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS
SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL
NT seq 3732 nt NT seq  +upstreamnt  +downstreamnt
atgggtgacatgaccaacagcgacttttactccaaaaaccaaagaaatgagtcgagccat
gggggcgagttcgggtgcacaatggaggagctccgctccctcatggagctgcggggcact
gaggctgtggtcaagatcaaggagacttatggggacaccgaagccatctgccggcgcctc
aaaacctcacctgttgaaggtttgccgggcaccgctccagacctggaaaagagaaagcaa
atttttgggcaaaactttatacctccaaagaagccaaaaaccttcctgcagctcgtgtgg
gaggcgctgcaggacgtgacgctcatcatcctggagattgccgccatcatctccctgggg
ctgtccttctaccacccgcccggcgagggcaacgaaggatgtgcgacggcccagggtggg
gcagaggatgaaggagaggcagaggcaggttggatcgagggggccgccattctcctctca
gttatctgtgtggtcctggtcacggccttcaatgactggagcaaagagaaacagttccgg
ggcctgcagagccgcatcgagcaggaacagaaatttaccgtggtccgggctggccaggtg
gtccagatccctgtggctgagatcgtggttggggacatagcccaggtcaaatatggtgac
ctcctccctgccgacggcctcttcatccagggcaatgacctcaagattgatgaaagctcc
ctaactggagagtctgaccaggtgcgcaagtccgtggacaaggaccccatgctgctgtca
ggaacccacgtgatggagggctcaggacggatgttggtgactgctgtgggtgtgaactct
cagactggcatcatctttaccctcctgggggctggtggtgaagaggaagagaagaaagac
aaaaaaggtgtgaagaagggggatggccttcagctaccagcagcagacggtgcggcagct
tcaaatgctgcagatagtgcgaatgccagcctagtcaatggtaaaatgcaggatggcaat
gtggacgccagccagagcaaagccaaacaacaggacggggcagccgccatggagatgcag
cccctcaagagtgccgagggcggcgacgctgacgacaggaagaaggccagcatgcacaag
aaggagaagtccgtgctgcagggcaagctcaccaagctggctgtgcagatcgggaaggcg
ggcttggtgatgtcagccatcacggtgatcatcctggtgctctacttcactgtggacacc
ttcgtggtcaacaagaagccgtggctgcctgagtgcacgcccgtctacgtgcagtacttt
gtcaagttcttcatcattggcgtgacggtgctggtggtcgccgtgcccgaggggctccct
ctggccgtcaccatctcgttggcctattcggtgaagaaaatgatgaaggacaacaacctg
gtacgccacctggatgcctgtgagaccatgggcaatgccacagccatctgctcagacaag
acaggcacgctgaccaccaatcgcatgacagtggtacaggcctatgtcggcgacgtccac
tataaagagatccccgaccccagctccatcaacaccaagaccatggagctgctgatcaat
gccatcgccatcaacagcgcctacaccaccaagattctgcccccagagaaggagggcgcc
ctgcctcggcaggtgggcaacaagacggagtgcggcctgctgggcttcgtgctggacctg
aagcaggactacgagcccgtgcgcagccagatgccagaggagaagttgtacaaagtgtac
accttcaactccgtgcgcaagtccatgagcactgtcatcaagctgcccgacgagagcttc
cgcatgtacagcaagggggcttctgagatcgtgctcaagaagtgctgcaaaatcctcaat
ggggcgggagagcctcgtgtcttccggccccgcgaccgggacgagatggtaaagaaggtg
attgagcccatggcttgcgatgggctccgcactatctgcgtggcctaccgcgacttcccc
agcagcccggagccggactgggacaatgagaatgacatcctcaacgaactcacctgcatc
tgcgtggtgggcatcgaggacccggtgcggccagaggtcccagaagccatccgcaagtgc
cagcgggcaggcatcacggtccgcatggtcactggcgacaatatcaacacggctcgggcc
atcgccatcaagtgtggcatcatccatcctggggaggactttctgtgcctcgagggcaag
gagttcaacaggaggatccgcaacgagaagggggagattgagcaggagcgaattgacaag
atctggccaaagctgcgggtgctggctcgctcctccccaacggacaagcataccctggtt
aaaggcatcatcgacagcacacacactgagcagcggcaggtggtggccgtgacgggggac
gggaccaacgacgggcctgcactcaagaaggccgacgtgggcttcgccatgggcatcgca
ggcactgacgtggccaaggaggcctcagacatcatcctgacagacgacaatttcagcagc
atcgtcaaggcagtgatgtggggccgcaacgtctatgacagcatctccaaattcttgcag
ttccagctcaccgtcaacgtggtggccgtgattgtggccttcacaggcgcctgcatcacg
caggactcccctctgaaggccgtgcagatgctctgggtgaacctcatcatggacacgttt
gcctcgctggcactggccactgagccgcccacggagaccctgctgctgaggaagccgtac
ggccgcaacaagccgctcatctccaggaccatgatgaagaacatcctgggccatgctgtc
taccagcttgccctcatcttcaccctgctctttgttggcgagaagatgttccagatcgac
agcgggaggaacgcgcccctgcattcgccaccctcagaacattacaccatcatcttcaac
accttcgtcatgatgcagctcttcaacgagatcaacgcccgcaagatccacggcgagcgc
aatgtctttgacggcatcttccggaaccccatcttctgcaccatcgtgctgggcaccttt
gccatccagatagtgatcgtgcagtttggagggaagccattcagctgctctccactgcag
ctggaccagtggatgtggtgcatattcattgggttaggagagctcgtttggggccaggtc
atcgccaccatcccgaccagcagactcaagttcctcaaggaggcaggcaggctcacacag
aaggaggagatcccggaggaggagctcaacgaggacgtggaggagatcgaccacgcggag
cgggagctgcggcggggccagatcctgtggttccgaggcctgaatcggatccagacacag
atccgcgtcgtgaaggcgttccgtagctctctctatgaaggtttagaaaagcctgaatct
cgaacctccatccataacttcatggctcatcctgaattccggatcgaagattcccagccc
cacatccccctcattgatgacaccgacctggaagaagatgccgcgctcaagcagaactcg
agcccgccgtcatccctcaacaagaacaacagcgccatcgacagtgggatcaacctgacg
accgacacaagcaaatcagctacctcttcaagtccagggagccccatccacagcctggag
acgtcgctttag

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