KEGG   Homo sapiens (human): 51166
Entry
51166             CDS       T01001                                 
Symbol
AADAT, KAT2, KATII, KYAT2
Name
(RefSeq) aminoadipate aminotransferase
  KO
K00825  kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00310  Lysine degradation
hsa00380  Tryptophan metabolism
hsa01100  Metabolic pathways
hsa01210  2-Oxocarboxylic acid metabolism
Module
hsa_M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Network
nt06036  Lysine degradation
  Element
N01685  Lysine degradation 1
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    51166 (AADAT)
   00310 Lysine degradation
    51166 (AADAT)
   00380 Tryptophan metabolism
    51166 (AADAT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    51166 (AADAT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.7  kynurenine---oxoglutarate transaminase
     51166 (AADAT)
    2.6.1.39  2-aminoadipate transaminase
     51166 (AADAT)
Amino acid related enzymes [BR:hsa01007]
 Aminotransferase (transaminase)
  Class I
   51166 (AADAT)
SSDB
Motif
Pfam: Aminotran_1_2 Asp_aminotransf
Other DBs
NCBI-GeneID: 51166
NCBI-ProteinID: NP_001273612
OMIM: 611754
HGNC: 17929
Ensembl: ENSG00000109576
UniProt: Q8N5Z0 Q4W5N8
Structure
Position
4:complement(170060222..170094292)
AA seq 425 aa
MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKT
IQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQG
LCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKP
EDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNK
FRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQ
LMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKV
KGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQL
IKESL
NT seq 1278 nt   +upstreamnt  +downstreamnt
atgaattacgcacggttcatcacggcagcgagcgcagccagaaacccttctcccatccgg
accatgactgacatattgagcagaggaccaaaatcgatgatctccttggctggtggctta
ccaaatccaaacatgtttccttttaagactgccgtaatcactgtagaaaatggaaagacc
atccaatttggagaagagatgatgaagagagcacttcagtattctccgagtgctggaatt
ccagagcttttgtcctggctaaaacagttacaaataaaattgcataatcctcctaccatc
cattacccacccagtcaaggacaaatggatctatgtgtcacatctggcagccaacaaggt
ctttgtaaggtgtttgaaatgatcattaatcctggagataatgtcctcctagatgaacct
gcttattcaggaactcttcaaagtctgcacccactgggctgcaacattattaatgttgcc
agtgatgaaagtgggattgttccagattccctaagagacatactttccagatggaaacca
gaagatgcaaagaatccccagaaaaacacccccaaatttctttatactgttccaaatggc
aacaaccctactggaaactcattaaccagtgaacgcaaaaaggaaatctatgagcttgca
agaaaatatgatttcctcataatagaagatgatccttactattttctccagtttaacaag
ttcagggtaccaacatttctttccatggatgttgatggacgtgtcatcagagctgactct
ttttcaaaaatcatttcctctgggttgagaataggatttttaactggtccaaaaccctta
atagagagagttattttacacatacaagtttcaacattgcaccccagcacttttaaccag
ctcatgatatcacagcttctacacgaatggggagaagaaggtttcatggctcatgtagac
agggttattgatttctatagtaaccagaaggatgcaatactggcagctgcagacaagtgg
ttaactggtttggcagaatggcatgttcctgctgctggaatgtttttatggattaaagtt
aaaggcattaatgatgtaaaagaactgattgaagaaaaggccgttaagatgggggtatta
atgctccctggaaatgctttctacgtcgatagctcagctcctagcccttacttgagagca
tccttctcttcagcttctccagaacagatggatgtggccttccaggtattagcacaactt
ataaaagaatctttatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (15)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (22)   
   RefSeq(nuc) (12)   
   GenBank (5)   
   EMBL (5)   
3D Structure (17)   
   PDB (17)   
Protein domain (2)   
   Pfam (2)   
All databases (93)   

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