KEGG   Homo sapiens (human): 5230Help
Entry
5230              CDS       T01001                                 

Gene name
PGK1, HEL-S-68p, MIG10, PGKA
Definition
phosphoglycerate kinase 1 (EC:2.7.2.3)
Orthology
K00927  
phosphoglycerate kinase [EC:2.7.2.3]
Organism
hsa  Homo sapiens (human)
Pathway
Glycolysis / Gluconeogenesis
Metabolic pathways
Carbon metabolism
Biosynthesis of amino acids
HIF-1 signaling pathway
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Glycolysis, core module involving three-carbon compounds
Gluconeogenesis, oxaloacetate => fructose-6P
Disease
H00664  
Anemia due to disorders of glycolytic enzymes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    5230 (PGK1)
   01230 Biosynthesis of amino acids
    5230 (PGK1)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    5230 (PGK1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    5230 (PGK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.3  phosphoglycerate kinase
     5230 (PGK1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   5230 (PGK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
UniProt: 
Structure
PDB: 

Jmol
Position
Xq13.3
AA seq 417 aa AA seqDB search
MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL
MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE
NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN
LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM
AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ
ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV
KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI
NT seq 1254 nt NT seq  +upstreamnt  +downstreamnt
atgtcgctttctaacaagctgacgctggacaagctggacgttaaagggaagcgggtcgtt
atgagagtcgacttcaatgttcctatgaagaacaaccagataacaaacaaccagaggatt
aaggctgctgtcccaagcatcaaattctgcttggacaatggagccaagtcggtagtcctt
atgagccacctaggccggcctgatggtgtgcccatgcctgacaagtactccttagagcca
gttgctgtagaactcaaatctctgctgggcaaggatgttctgttcttgaaggactgtgta
ggcccagaagtggagaaagcctgtgccaacccagctgctgggtctgtcatcctgctggag
aacctccgctttcatgtggaggaagaagggaagggaaaagatgcttctgggaacaaggtt
aaagccgagccagccaaaatagaagctttccgagcttcactttccaagctaggggatgtc
tatgtcaatgatgcttttggcactgctcacagagcccacagctccatggtaggagtcaat
ctgccacagaaggctggtgggtttttgatgaagaaggagctgaactactttgcaaaggcc
ttggagagcccagagcgacccttcctggccatcctgggcggagctaaagttgcagacaag
atccagctcatcaataatatgctggacaaagtcaatgagatgattattggtggtggaatg
gcttttaccttccttaaggtgctcaacaacatggagattggcacttctctgtttgatgaa
gagggagccaagattgtcaaagacctaatgtccaaagctgagaagaatggtgtgaagatt
accttgcctgttgactttgtcactgctgacaagtttgatgagaatgccaagactggccaa
gccactgtggcttctggcatacctgctggctggatgggcttggactgtggtcctgaaagc
agcaagaagtatgctgaggctgtcactcgggctaagcagattgtgtggaatggtcctgtg
ggggtatttgaatgggaagcttttgcccggggaaccaaagctctcatggatgaggtggtg
aaagccacttctaggggctgcatcaccatcataggtggtggagacactgccacttgctgt
gccaaatggaacacggaggataaagtcagccatgtgagcactgggggtggtgccagtttg
gagctcctggaaggtaaagtccttcctggggtggatgctctcagcaatatttag

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