KEGG   Homo sapiens (human): 5333Help
Entry
5333              CDS       T01001                                 

Gene name
PLCD1, NDNC3, PLC-III
Definition
phospholipase C, delta 1 (EC:3.1.4.11)
Orthology
K05857  
phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
Organism
hsa  Homo sapiens (human)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Calcium signaling pathway
Phosphatidylinositol signaling system
Thyroid hormone signaling pathway
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Disease
H01307  
Nonsyndromic congenital nail disorder (NDNC)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    5333 (PLCD1)
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    5333 (PLCD1)
   04070 Phosphatidylinositol signaling system
    5333 (PLCD1)
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    5333 (PLCD1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     5333 (PLCD1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
3p22-p21.3
AA seq 777 aa AA seqDB search
MQCLGIRSRSRSRELYLQERSLKVAALNGRRLGLQDDEDLQALLKGSQLLKVKSSSWRRE
RFYKLQEDCKTIWQESRKVMRTPESQLFSIEDIQEVRMGHRTEGLEKFARDVPEDRCFSI
VFKDQRNTLDLIAPSPADAQHWVLGLHKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNK
MSFKELQNFLKELNIQVDDSYARKIFRECDHSQTDSLEDEEIEAFYKMLTQRVEIDRTFA
EAAGSGETLSVDQLVTFLQHQQREEAAGPALALSLIERYEPSETAKAQRQMTKDGFLMYL
LSADGSAFSLAHRRVYQDMGQPLSHYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRC
LELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQR
VMARHLHAILGPMLLNRPLDGVTNSLPSPEQLKGKILLKGKKLGGLLPPGGEGGPEATVV
SDEDEAAEMEDEAVRSRVQHKPKEDKLRLAQELSDMVIYCKSVHFGGFSSPGTPGQAFYE
MASFSENRALRLLQESGNGFVRHNVGHLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNF
QTPGPEMDVYQGRFQDNGACGYVLKPAFLRDPNGTFNPRALAQGPWWARKRLNIRVISGQ
QLPKVNKNKNSIVDPKVTVEIHGVSRDVASRQTAVITNNGFNPWWDTEFAFEVVVPDLAL
IRFLVEDYDASSKNDFIGQSTIPLNSLKQGYRHVHLMSKNGDQHPSATLFVKISLQD
NT seq 2334 nt NT seq  +upstreamnt  +downstreamnt
atgcagtgcctggggatccggagccggagccgctccagggagctctacctgcaggagcgg
agccttaaggtggcggcgctcaatggacggaggctgggcctacaggatgatgaggatcta
caggcgctgctgaagggcagccagctcctgaaggtgaagtccagctcatggaggagagag
cgcttctacaagttgcaggaggactgcaagaccatctggcaggagtcccgcaaggtcatg
cggaccccggagtcccagctgttctccatcgaggacattcaggaggtgcgaatggggcac
cgcacggagggtctggagaagttcgcccgtgatgtgcccgaggaccgctgcttctccatt
gtcttcaaggaccagcgcaatacactagacctcatcgccccatcgccagctgatgcccag
cactgggtgctggggctgcacaagatcatccaccactcaggctccatggaccagcgtcag
aagctacagcactggattcactcctgcttgcgaaaagctgacaaaaacaaggacaacaag
atgagcttcaaggagctgcagaacttcctgaaggagctcaacatccaggtggacgacagc
tatgcccggaagatcttcagggagtgtgaccactcccagacagactccctggaggacgag
gagattgaggccttctacaagatgctgacccagcgggtggagatcgaccgcaccttcgcc
gaggccgcgggctcaggggagactctgtcggtggatcagttagtgacgttcctgcagcac
cagcagcgggaggaggcggcagggcctgcgctggccctctccctcattgagcgctacgag
cccagcgagactgccaaggcgcagcggcagatgaccaaggacggcttcctcatgtactta
ctgtcggctgacggcagcgccttcagcctggcacaccgccgtgtctaccaggacatgggc
cagccacttagccactacctggtgtcctcttcacacaacacctacctgctggaggaccag
ctagccgggcccagcagcactgaagcctacatccgggcactgtgcaaaggctgccgatgc
ctggagcttgactgctgggacgggcccaaccaggaaccaatcatctaccacggctatact
ttcacttccaagatcctcttctgcgatgtgctcagggccatccgggactatgccttcaag
gcgtccccctaccctgtcatcctatccctggagaaccactgcacactggagcagcagcgc
gtgatggcgcggcacctgcatgccatcctgggccccatgctgttgaaccgaccactggat
ggggtcaccaacagcctgccctcccctgagcaactgaaggggaagatcctgctgaagggg
aagaagctcggggggctcctgccccctggaggggagggtggccctgaggccactgtggtg
tcagacgaagacgaggctgctgagatggaggatgaggcagtgaggagccgtgtgcagcac
aagcccaaggaggacaagctcaggctagcacaggagctctctgacatggtcatttactgc
aagagtgtccactttgggggcttctccagtcctggcacccctggacaggccttctacgag
atggcgtccttctctgagaaccgtgcccttcgactgctccaagaatcaggaaacggcttt
gtccgccacaacgtggggcacctgagcagaatctacccggctggatggagaacagactcc
tccaactacagccccgtggagatgtggaatgggggctgccagatcgtggccctgaatttc
cagacacctgggccagagatggacgtgtaccagggccgcttccaggacaacggggcctgt
gggtacgtgctgaagcccgccttcctgcgagaccccaacggcacctttaacccccgcgcc
ctggctcaggggccctggtgggcacggaagcggctcaacatcagggtcatttcggggcag
cagctgccaaaagtcaacaagaataagaattcaattgtggaccccaaagtgacagtggag
atccatggcgtgagccgggacgtggccagccgccagactgctgtcatcaccaacaatggt
ttcaacccatggtgggacacggagtttgcgtttgaggtagttgtgcctgaccttgccctc
atccgcttcttggtggaagattatgatgcctcctccaagaatgacttcattggccagagt
accatccccttgaacagcctcaagcaaggataccgccatgtccacctcatgtctaagaac
ggggaccagcatccatcagccaccctctttgtgaagatctccctccaggactag

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