KEGG T01001: 5434

Homo sapiens (human): 5434

Entry

5434 CDS T01001

Gene name

POLR2E, RPABC1, RPB5, XAP4, hRPB25, hsRPB5

Definition

polymerase (RNA) II (DNA directed) polypeptide E, 25kDa (EC:2.7.7.6)

Orthology

K03013

DNA-directed RNA polymerases I, II, and III subunit RPABC1

Organism

hsa Homo sapiens (human)

Pathway

hsa00230	Purine metabolism
hsa00240	Pyrimidine metabolism
hsa01100	Metabolic pathways
hsa03020	RNA polymerase
hsa04623	Cytosolic DNA-sensing pathway
hsa05016	Huntington's disease
hsa05169	Epstein-Barr virus infection

Module

hsa_M00180	RNA polymerase II, eukaryotes
hsa_M00181	RNA polymerase III, eukaryotes
hsa_M00182	RNA polymerase I, eukaryotes

Class

Metabolism; Nucleotide metabolism; Purine metabolism [PATH:hsa00230]
Metabolism; Nucleotide metabolism; Pyrimidine metabolism [PATH:hsa00240]
Genetic Information Processing; Transcription; RNA polymerase [PATH:hsa03020]
Organismal Systems; Immune system; Cytosolic DNA-sensing pathway [PATH:hsa04623]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:hsa05016]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:hsa05169]

SSDB

Motif

Pfam:

RNA_pol_Rpb5_C RNA_pol_Rpb5_N EIAV_Rev

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

UniProt:

Position

19p13.3

AA seq 210 aa
MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQFGDKPSEGRPRRTDLTV
LVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVD
MAPKYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVA
RYFGIKRGQVVKIIRPSETAGRYITYRLVQ

NT seq 633 nt +upstreamnt +downstreamnt
atggacgacgaggaggagacgtaccggctctggaaaatccgcaagaccatcatgcagctg
tgccacgaccgtggctatctggtgacccaggacgagcttgaccagaccctggaggagttc
aaagcccaatttggggacaagccgagtgaggggcggccgcggcgcacggacctcaccgtg
ctggtggcccacaacgatgaccccaccgaccagatgtttgtgttctttccagaggagccc
aaggtgggcatcaagaccatcaaggtgtactgccagcgcatgcaggaggagaacatcaca
cgggctctcatcgtggtgcagcagggcatgacaccctccgccaagcagtccctggtcgac
atggcccccaagtacatcctggagcagtttctgcagcaggagctgctcatcaacatcacg
gagcacgagctagtccctgagcacgtcgtcatgaccaaggaggaggtgacagagctgctg
gcccgatataagctccgagagaaccagctgcccaggatccaggcgggggaccctgtggcg
cgctactttgggataaagcgtgggcaggtggtgaagatcatccggcccagtgagacggct
ggcaggtacatcacctaccggctggtgcagtag

All links

Pathway (10)   
   KEGG PATHWAY (7)   
   KEGG MODULE (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (9)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (3)   
   Pfam (3)   
All databases (63)   

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