KEGG   Homo sapiens (human): 5468Help
Entry
5468              CDS       T01001                                 

Gene name
PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma
Definition
peroxisome proliferator-activated receptor gamma
Orthology
K08530  
peroxisome proliferator-activated receptor gamma
Organism
hsa  Homo sapiens (human)
Pathway
PPAR signaling pathway
AMPK signaling pathway
Osteoclast differentiation
Huntington's disease
Pathways in cancer
Transcriptional misregulation in cancer
Thyroid cancer
Disease
H00032  
Thyroid cancer
H00409  
Type II diabetes mellitus
H00420  
Familial partial lipodystrophy (FPL)
Drug target
Troglitazone: 
Rosiglitazone: 
Pioglitazone: 
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04152 AMPK signaling pathway
    5468 (PPARG)
 Organismal Systems
  Endocrine system
   03320 PPAR signaling pathway
    5468 (PPARG)
  Development
   04380 Osteoclast differentiation
    5468 (PPARG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    5468 (PPARG)
   05202 Transcriptional misregulation in cancers
    5468 (PPARG)
   05216 Thyroid cancer
    5468 (PPARG)
  Neurodegenerative diseases
   05016 Huntington's disease
    5468 (PPARG)
Transcription factors [BR:hsa03000]
 Eukaryotic Type
  Zinc finger
   Cys4 thyroid hormone-like
    5468 (PPARG)
Nuclear receptors [BR:hsa03310]
 1. Thyroid hormone like
  1C. Peroxisome proliferator-activated receptor (PPAR)
   5468 (PPARG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
3p25
AA seq 477 aa AA seqDB search
MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP
VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG
FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI
RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK
TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA
KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF
GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ
LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
NT seq 1434 nt NT seq  +upstreamnt  +downstreamnt
atgaccatggttgacacagagatgccattctggcccaccaactttgggatcagctccgtg
gatctctccgtaatggaagaccactcccactcctttgatatcaagcccttcactactgtt
gacttctccagcatttctactccacattacgaagacattccattcacaagaacagatcca
gtggttgcagattacaagtatgacctgaaacttcaagagtaccaaagtgcaatcaaagtg
gagcctgcatctccaccttattattctgagaagactcagctctacaataagcctcatgaa
gagccttccaactccctcatggcaattgaatgtcgtgtctgtggagataaagcttctgga
tttcactatggagttcatgcttgtgaaggatgcaagggtttcttccggagaacaatcaga
ttgaagcttatctatgacagatgtgatcttaactgtcggatccacaaaaaaagtagaaat
aaatgtcagtactgtcggtttcagaaatgccttgcagtggggatgtctcataatgccatc
aggtttgggcggatgccacaggccgagaaggagaagctgttggcggagatctccagtgat
atcgaccagctgaatccagagtccgctgacctccgggccctggcaaaacatttgtatgac
tcatacataaagtccttcccgctgaccaaagcaaaggcgagggcgatcttgacaggaaag
acaacagacaaatcaccattcgttatctatgacatgaattccttaatgatgggagaagat
aaaatcaagttcaaacacatcacccccctgcaggagcagagcaaagaggtggccatccgc
atctttcagggctgccagtttcgctccgtggaggctgtgcaggagatcacagagtatgcc
aaaagcattcctggttttgtaaatcttgacttgaacgaccaagtaactctcctcaaatat
ggagtccacgagatcatttacacaatgctggcctccttgatgaataaagatggggttctc
atatccgagggccaaggcttcatgacaagggagtttctaaagagcctgcgaaagcctttt
ggtgactttatggagcccaagtttgagtttgctgtgaagttcaatgcactggaattagat
gacagcgacttggcaatatttattgctgtcattattctcagtggagaccgcccaggtttg
ctgaatgtgaagcccattgaagacattcaagacaacctgctacaagccctggagctccag
ctgaagctgaaccaccctgagtcctcacagctgtttgccaagctgctccagaaaatgaca
gacctcagacagattgtcacggaacacgtgcagctactgcaggtgatcaagaagacggag
acagacatgagtcttcacccgctcctgcaggagatctacaaggacttgtactag

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