KEGG   Homo sapiens (human): 54822
Entry
54822             CDS       T01001                                 
Symbol
TRPM7, ALSPDC, CHAK, CHAK1, LTRPC7, LTrpC-7, TRP-PLIK
Name
(RefSeq) transient receptor potential cation channel subfamily M member 7
  KO
K04982  transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04217  Necroptosis
hsa04218  Cellular senescence
hsa04621  NOD-like receptor signaling pathway
hsa04978  Mineral absorption
Disease
H00058  Amyotrophic lateral sclerosis (ALS)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    54822 (TRPM7)
   04218 Cellular senescence
    54822 (TRPM7)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    54822 (TRPM7)
  09154 Digestive system
   04978 Mineral absorption
    54822 (TRPM7)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    54822 (TRPM7)
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    54822 (TRPM7)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     54822 (TRPM7)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  Alpha family [OT]
   54822 (TRPM7)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   54822 (TRPM7)
SSDB
Motif
Pfam: LSDAT_euk Alpha_kinase TRPM_tetra LSDAT_prok Ion_trans AAA_19
Other DBs
NCBI-GeneID: 54822
NCBI-ProteinID: NP_060142
OMIM: 605692
HGNC: 17994
Ensembl: ENSG00000092439
UniProt: Q96QT4
Position
15:complement(50557158..50686797)
AA seq 1865 aa
MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAM
KYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVI
LQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGV
AKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNN
LHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTV
LEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQNE
ALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQLILTLAWDRV
DIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNT
KQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSL
GGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVMEEGKK
KRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYR
SMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNST
CLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKTKA
EMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEMEIQMKSKKLP
ITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEK
VREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVA
GRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKA
ILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAVY
LFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVS
LFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVT
FERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKV
HNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNNPFHCNILMK
DDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHGVELLKIFNK
NQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATEGDNTEFGAF
VGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFTDCHRTSIPVHSKQAEKIS
RRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDTNYYYSAVER
NNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKIEFLSKEEMG
GGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRA
AQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIP
TNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGE
DAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNS
VRLML
NT seq 5598 nt   +upstreamnt  +downstreamnt
atgtcccagaaatcctggatagaaagcactttgaccaagagggaatgtgtatatattata
ccaagttccaaggaccctcacagatgccttccaggatgtcaaatttgtcagcaactcgtc
aggtgtttttgtggtcgcttggtcaagcaacatgcttgttttactgcaagtcttgccatg
aaatactcagatgtgaaattgggtgaccattttaatcaggcaatagaagaatggtctgtg
gaaaagcatacagaacagagcccaacggatgcttatggagtcataaattttcaagggggt
tctcattcctacagagctaagtatgtgaggctatcatatgacaccaaacctgaagtcatt
ctgcaacttctgcttaaagaatggcaaatggagttacccaaacttgttatctctgtacat
gggggcatgcagaaatttgagcttcacccacgaatcaagcagttgcttggaaaaggtctt
attaaagctgcagttacaactggagcctggattttaactggaggagtaaacacaggtgtg
gcaaaacatgttggagatgccctcaaagaacatgcttccagatcatctcgaaagatttgc
actatcggaatagctccatggggagtgattgaaaacagaaatgatcttgttgggagagat
gtggttgctccttatcaaaccttattgaaccccctgagcaaattgaatgttttgaataat
ctgcattcccatttcatattggtggatgatggcactgttggaaagtatggggcggaagtc
agactgagaagagaacttgaaaaaactattaatcagcaaagaattcatgctaggattggc
cagggtgtccctgtggtggcacttatatttgagggtgggccaaatgttatcctcacagtt
cttgaataccttcaggaaagcccccctgttccagtagttgtgtgtgaaggaacaggcaga
gctgcagatctgctagcgtatattcataaacaaacagaagaaggagggaatcttcctgat
gcagcagagcccgatattatttccactatcaaaaaaacatttaactttggccagaatgaa
gcacttcatttatttcaaacactgatggagtgcatgaaaagaaaggagcttatcactgtt
ttccatattgggtcagatgaacatcaagatatagatgtagcaatacttactgcactgcta
aaaggtactaatgcatctgcatttgaccagcttatccttacattggcatgggatagagtt
gacattgccaaaaatcatgtatttgtttatggacagcagtggctggttggatccttggaa
caagctatgcttgatgctcttgtaatggatagagttgcatttgtaaaacttcttattgaa
aatggagtaagcatgcataaattccttaccattccgagactggaagaactttacaacact
aaacaaggtccaactaatccaatgctgtttcatcttgttcgagacgtcaaacagggaaat
cttcctccaggatataagatcactctgattgatataggacttgttattgaatatctcatg
ggaggaacctacagatgcacctatactaggaaacgttttcgattaatatataatagtctt
ggtggaaataatcggaggtctggccgaaatacctccagcagcactcctcagttgcgaaag
agtcatgaatcttttggcaatagggcagataaaaaggaaaaaatgaggcataaccatttc
attaagacagcacagccctaccgaccaaagattgatacagttatggaagaaggaaagaag
aaaagaaccaaagatgaaattgtagacattgatgatccagaaaccaagcgctttccttat
ccacttaatgaacttttaatttgggcttgccttatgaagaggcaggtcatggcccgtttt
ttatggcaacatggtgaagaatcaatggctaaagcattagttgcctgtaagatctatcgt
tcaatggcatatgaagcaaagcagagtgacctggtagatgatacttcagaagaactaaaa
cagtattccaatgattttggtcagttggccgttgaattattagaacagtccttcagacaa
gatgaaaccatggctatgaaattgctcacttatgaactgaagaactggagtaattcaacc
tgccttaagttagcagtttcttcaagacttagaccttttgtagctcacacctgtacacaa
atgttgttatctgatatgtggatgggaaggctgaatatgaggaaaaattcctggtacaag
gtcatactaagcattttagttccacctgccatattgctgttagagtataaaactaaggct
gaaatgtcccatatcccacaatctcaagatgctcatcagatgacaatggatgacagcgaa
aacaactttcagaacataacagaagagatccccatggaagtgtttaaagaagtacggatt
ttggatagtaatgaaggaaagaatgagatggagatacaaatgaaatcaaaaaagcttcca
attacgcgaaagttttatgccttttatcatgcaccaattgtaaaattctggtttaacacg
ttggcatatttaggatttctgatgctttatacatttgtggttcttgtacaaatggaacag
ttaccttcagttcaagaatggattgttattgcttatatttttacttatgccattgagaaa
gtccgtgagatctttatgtctgaagctgggaaagtaaaccagaagattaaagtatggttt
agtgattacttcaacatcagtgatacaattgccataatttctttcttcattggatttgga
ctaagatttggagcaaaatggaactttgcaaatgcatatgataatcatgtttttgtggct
ggaagattaatttactgtcttaacataatattttggtatgtgcgtttgctagattttcta
gctgtaaatcaacaggcaggaccttatgtaatgatgattggaaaaatggtggccaatatg
ttctacattgtagtgattatggctcttgtattacttagttttggtgttcccagaaaggca
atactttatcctcatgaagcaccatcttggactcttgctaaagatatagtttttcaccca
tactggatgatttttggtgaagtttatgcatacgaaattgatgtgtgtgcaaatgattct
gttatccctcaaatctgtggtcctgggacgtggttgactccatttcttcaagcagtctac
ctctttgtacagtatatcattatggttaatcttcttattgcatttttcaacaatgtgtat
ttacaagtgaaggcaatttccaatattgtatggaagtaccagcgttatcattttattatg
gcttatcatgagaaaccagttctgcctcctccacttatcattcttagccatatagtttct
ctgttttgctgcatatgtaagagaagaaagaaagataagacttccgatggaccaaaactt
ttcttaacagaagaagatcaaaagaaacttcatgattttgaagagcagtgtgttgaaatg
tatttcaatgaaaaagatgacaaatttcattctgggagtgaagagagaattcgtgtcact
tttgaaagagtggaacagatgtgcattcagattaaagaagttggagatcgtgtcaactac
ataaaaagatcattacaatcattagattctcaaattggccatttgcaagatctttcagcc
ctgacggtagatacattaaaaacactcactgcccagaaagcgtcggaagctagcaaagtt
cataatgaaatcacacgagaactgagcatttccaaacacttggctcaaaaccttattgat
gatggtcctgtaagaccttctgtatggaaaaagcatggtgttgtaaatacacttagctcc
tctcttcctcaaggtgatcttgaaagtaataatccttttcattgtaatattttaatgaaa
gatgacaaagatccccagtgtaatatatttggtcaagacttacctgcagtaccccagaga
aaagaatttaattttccagaggctggttcctcttctggtgccttattcccaagtgctgtt
tcccctccagaactgcgacagagactacatggggtagaactcttaaaaatatttaataaa
aatcaaaaattaggcagttcatctactagcataccacatctgtcatccccaccaaccaaa
ttttttgttagtacaccatctcagccaagttgcaaaagccacttggaaactggaaccaaa
gatcaagaaactgtttgctctaaagctacagaaggagataatacagaatttggagcattt
gtaggacacagagatagcatggatttacagaggtttaaagaaacatcaaacaagataaaa
atactatccaataacaatacttctgaaaacactttgaaacgagtgagttctcttgctgga
tttactgactgtcacagaacttccattcctgttcattcaaaacaagcagaaaaaatcagt
agaaggccatctaccgaagacactcatgaagtagattccaaagcagctttaataccggat
tggttacaagatagaccatcaaacagagaaatgccatctgaagaaggaacattaaatggt
ctcacttctccatttaagccagctatggatacaaattactattattcagctgtggaaaga
aataacttgatgaggttatcacagagcattccatttacacctgtgcctccaagaggggag
cctgtcacagtgtatcgtttggaagagagttcacccaacatactaaataacagcatgtct
tcttggtcacaactaggcctctgtgccaaaatagagtttttaagcaaagaggagatggga
ggaggtttacgaagagctgtcaaagtacagtgtacctggtcagaacatgatatcctcaaa
tcagggcatctttatattatcaaatcttttcttccagaggtggttaatacatggtcaagt
atttacaaagaagatacagttctgcatctctgtctgagagaaattcaacaacagagagca
gcacaaaagcttacgtttgcctttaatcaaatgaaacccaaatccataccatattctcca
aggttccttgaagttttcctgctgtattgccattcagcaggacagtggtttgctgtggaa
gaatgtatgactggagaatttagaaaatacaacaataataatggagatgagattattcca
actaatactctggaagagatcatgctagcctttagccactggacttacgaatatacaaga
ggggagttactggtacttgatttgcaaggtgttggtgaaaatttgactgacccatctgtg
ataaaagcagaagaaaagagatcctgtgatatggtttttggcccagcaaatctaggagaa
gatgcaattaaaaacttcagagcaaaacatcactgtaattcttgctgtagaaagcttaaa
cttccagatctgaagaggaatgattatacgcctgataaaattatatttcctcaggatgag
ccttcagatttgaatcttcagcctggaaattccaccaaagaatcagaatcaactaattct
gttcgtctgatgttataa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (29)   
   RefSeq(nuc) (5)   
   GenBank (12)   
   EMBL (12)   
Protein domain (6)   
   Pfam (6)   
All databases (80)   

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