KEGG   Homo sapiens (human): 5499Help
Entry
5499              CDS       T01001                                 

Gene name
PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A
Definition
protein phosphatase 1, catalytic subunit, alpha isozyme (EC:3.1.3.16)
Orthology
K06269  
protein phosphatase 1, catalytic subunit [EC:3.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
mRNA surveillance pathway
Oocyte meiosis
Vascular smooth muscle contraction
Hippo signaling pathway
Focal adhesion
Long-term potentiation
Dopaminergic synapse
Regulation of actin cytoskeleton
Insulin signaling pathway
Amphetamine addiction
Alcoholism
Herpes simplex infection
Proteoglycans in cancer
Class
Genetic Information Processing; Translation; mRNA surveillance pathway [PATH:hsa03015]
Environmental Information Processing; Signal transduction; Hippo signaling pathway [PATH:hsa04390]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:hsa04810]
Cellular Processes; Cell growth and death; Oocyte meiosis [PATH:hsa04114]
Cellular Processes; Cell communication; Focal adhesion [PATH:hsa04510]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:hsa04910]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:hsa04270]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:hsa04728]
Organismal Systems; Nervous system; Long-term potentiation [PATH:hsa04720]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:hsa05205]
Human Diseases; Substance dependence; Amphetamine addiction [PATH:hsa05031]
Human Diseases; Substance dependence; Alcoholism [PATH:hsa05034]
Human Diseases; Infectious diseases; Herpes simplex infection [PATH:hsa05168]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
11q13
AA seq 341 aa AA seqDB search
MSDSEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQ
PILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLA
YKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKI
FCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA
EVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETL
MCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 1026 nt NT seq  +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactcgatcatcgggcgcctgctggaagggtcc
agggtcctgacaccccattgcgccccagtgcagggctcgcggcctggcaagaatgtacag
ctgacagagaacgagatccgcggtctgtgcctgaaatcccgggagatttttctgagccag
cccattcttctggagctggaggcacccctcaagatctgcggtgacatacacggccagtac
tacgaccttctgcgactatttgagtatggcggtttccctcccgagagcaactacctcttt
ctgggggactatgtggacaggggcaagcagtccttggagaccatctgcctgctgctggcc
tataagatcaagtaccccgagaacttcttcctgctccgtgggaaccacgagtgtgccagc
atcaaccgcatctatggtttctacgatgagtgcaagagacgctacaacatcaaactgtgg
aaaaccttcactgactgcttcaactgcctgcccatcgcggccatagtggacgaaaagatc
ttctgctgccacggaggcctgtccccggacctgcagtctatggagcagattcggcggatc
atgcggcccacagatgtgcctgaccagggcctgctgtgtgacctgctgtggtctgaccct
gacaaggacgtgcagggctggggcgagaacgaccgtggcgtctcttttacctttggagcc
gaggtggtggccaagttcctccacaagcacgacttggacctcatctgccgagcacaccag
gtggtagaagacggctacgagttctttgccaagcggcagctggtgacacttttctcagct
cccaactactgtggcgagtttgacaatgctggcgccatgatgagtgtggacgagaccctc
atgtgctctttccagatcctcaagcccgccgacaagaacaaggggaagtacgggcagttc
agtggcctgaaccctggaggccgacccatcaccccaccccgcaattccgccaaagccaag
aaatag

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