KEGG   Homo sapiens (human): 5499Help
Entry
5499              CDS       T01001                                 

Gene name
PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A
Definition
protein phosphatase 1, catalytic subunit, alpha isozyme (EC:3.1.3.16)
Orthology
K06269  
serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
mRNA surveillance pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Hippo signaling pathway
Focal adhesion
Long-term potentiation
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Oxytocin signaling pathway
Amphetamine addiction
Alcoholism
Herpes simplex infection
Proteoglycans in cancer
Class
Genetic Information Processing; Translation; mRNA surveillance pathway [PATH:hsa03015]
Environmental Information Processing; Signal transduction; Hippo signaling pathway [PATH:hsa04390]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:hsa04810]
Cellular Processes; Cell growth and death; Oocyte meiosis [PATH:hsa04114]
Cellular Processes; Cell communication; Focal adhesion [PATH:hsa04510]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:hsa04910]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:hsa04921]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:hsa04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:hsa04270]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:hsa04728]
Organismal Systems; Nervous system; Long-term potentiation [PATH:hsa04720]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:hsa04750]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:hsa05205]
Human Diseases; Substance dependence; Amphetamine addiction [PATH:hsa05031]
Human Diseases; Substance dependence; Alcoholism [PATH:hsa05034]
Human Diseases; Infectious diseases; Herpes simplex infection [PATH:hsa05168]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
11q13
AA seq 341 aa AA seqDB search
MSDSEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQ
PILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLA
YKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKI
FCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA
EVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETL
MCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 1026 nt NT seq  +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactcgatcatcgggcgcctgctggaagggtcc
agggtcctgacaccccattgcgccccagtgcagggctcgcggcctggcaagaatgtacag
ctgacagagaacgagatccgcggtctgtgcctgaaatcccgggagatttttctgagccag
cccattcttctggagctggaggcacccctcaagatctgcggtgacatacacggccagtac
tacgaccttctgcgactatttgagtatggcggtttccctcccgagagcaactacctcttt
ctgggggactatgtggacaggggcaagcagtccttggagaccatctgcctgctgctggcc
tataagatcaagtaccccgagaacttcttcctgctccgtgggaaccacgagtgtgccagc
atcaaccgcatctatggtttctacgatgagtgcaagagacgctacaacatcaaactgtgg
aaaaccttcactgactgcttcaactgcctgcccatcgcggccatagtggacgaaaagatc
ttctgctgccacggaggcctgtccccggacctgcagtctatggagcagattcggcggatc
atgcggcccacagatgtgcctgaccagggcctgctgtgtgacctgctgtggtctgaccct
gacaaggacgtgcagggctggggcgagaacgaccgtggcgtctcttttacctttggagcc
gaggtggtggccaagttcctccacaagcacgacttggacctcatctgccgagcacaccag
gtggtagaagacggctacgagttctttgccaagcggcagctggtgacacttttctcagct
cccaactactgtggcgagtttgacaatgctggcgccatgatgagtgtggacgagaccctc
atgtgctctttccagatcctcaagcccgccgacaagaacaaggggaagtacgggcagttc
agtggcctgaaccctggaggccgacccatcaccccaccccgcaattccgccaaagccaag
aaatag

DBGET integrated database retrieval system