KEGG   Homo sapiens (human): 5500Help
Entry
5500              CDS       T01001                                 

Gene name
PPP1CB, HEL-S-80p, PP-1B, PP1B, PP1beta, PPP1CD
Definition
protein phosphatase 1, catalytic subunit, beta isozyme (EC:3.1.3.16 3.1.3.53)
Orthology
K06269  
serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
mRNA surveillance pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Hippo signaling pathway
Focal adhesion
Platelet activation
Long-term potentiation
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Oxytocin signaling pathway
Amphetamine addiction
Alcoholism
Herpes simplex infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Genetic Information Processing
  Translation
   03015 mRNA surveillance pathway
    5500 (PPP1CB)
 Environmental Information Processing
  Signal transduction
   04390 Hippo signaling pathway
    5500 (PPP1CB)
   04024 cAMP signaling pathway
    5500 (PPP1CB)
   04022 cGMP - PKG signaling pathway
    5500 (PPP1CB)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    5500 (PPP1CB)
  Cell growth and death
   04114 Oocyte meiosis
    5500 (PPP1CB)
  Cellular commiunity
   04510 Focal adhesion
    5500 (PPP1CB)
 Organismal Systems
  Immune system
   04611 Platelet activation
    5500 (PPP1CB)
  Endocrine system
   04910 Insulin signaling pathway
    5500 (PPP1CB)
   04921 Oxytocin signaling pathway
    5500 (PPP1CB)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5500 (PPP1CB)
   04270 Vascular smooth muscle contraction
    5500 (PPP1CB)
  Nervous system
   04728 Dopaminergic synapse
    5500 (PPP1CB)
   04720 Long-term potentiation
    5500 (PPP1CB)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    5500 (PPP1CB)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    5500 (PPP1CB)
  Substance dependence
   05031 Amphetamine addiction
    5500 (PPP1CB)
   05034 Alcoholism
    5500 (PPP1CB)
  Infectious diseases
   05168 Herpes simplex infection
    5500 (PPP1CB)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     5500 (PPP1CB)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     5500 (PPP1CB)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     5500 (PPP1CB)
Spliceosome [BR:hsa03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    5500 (PPP1CB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
2p23
AA seq 327 aa AA seqDB search
MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI
CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ
SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL
DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
KAKYQYGGLNSGRPVTPPRTANPPKKR
NT seq 984 nt NT seq  +upstreamnt  +downstreamnt
atggcggacggggagctgaacgtggacagcctcatcacccggctgctggaggtacgagga
tgtcgtccaggaaagattgtgcagatgactgaagcagaagttcgaggcttatgtatcaag
tctcgggagatctttctcagccagcctattcttttggaattggaagcaccgctgaaaatt
tgtggagatattcatggacaatatacagatttactgagattatttgaatatggaggtttc
ccaccagaagccaactatcttttcttaggagattatgtggacagaggaaagcagtctttg
gaaaccatttgtttgctattggcttataaaatcaaatatccagagaacttctttctctta
agaggaaaccatgagtgtgctagcatcaatcgcatttatggattctatgatgaatgcaaa
cgaagatttaatattaaattgtggaagaccttcactgattgttttaactgtctgcctata
gcagccattgtggatgagaagatcttctgttgtcatggaggattgtcaccagacctgcaa
tctatggagcagattcggagaattatgagacctactgatgtccctgatacaggtttgctc
tgtgatttgctatggtctgatccagataaggatgtgcaaggctggggagaaaatgatcgt
ggtgtttcctttacttttggagctgatgtagtcagtaaatttctgaatcgtcatgattta
gatttgatttgtcgagctcatcaggtggtggaagatggatatgaattttttgctaaacga
cagttggtaaccttattttcagccccaaattactgtggcgagtttgataatgctggtgga
atgatgagtgtggatgaaactttgatgtgttcatttcagatattgaaaccatctgaaaag
aaagctaaataccagtatggtggactgaattctggacgtcctgtcactccacctcgaaca
gctaatccgccgaagaaaaggtga

DBGET integrated database retrieval system