KEGG   Homo sapiens (human): 5535Help
Entry
5535              CDS       T01001                                 

Gene name
PPP3R2, PPP3RL
Definition
protein phosphatase 3, regulatory subunit B, beta (EC:3.1.3.16)
Orthology
K06268  
serine/threonine-protein phosphatase 2B regulatory subunit
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Oocyte meiosis
Apoptosis
Wnt signaling pathway
Axon guidance
VEGF signaling pathway
Osteoclast differentiation
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Long-term potentiation
Glutamatergic synapse
Oxytocin signaling pathway
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
Amphetamine addiction
Tuberculosis
HTLV-I infection
Drug target
Tacrolimus: 
Pimecrolimus: 
Ciclosporin: 
Tacrolimus: 
Voclosporin: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    5535 (PPP3R2)
   04310 Wnt signaling pathway
    5535 (PPP3R2)
   04370 VEGF signaling pathway
    5535 (PPP3R2)
   04020 Calcium signaling pathway
    5535 (PPP3R2)
   04022 cGMP - PKG signaling pathway
    5535 (PPP3R2)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    5535 (PPP3R2)
   04210 Apoptosis
    5535 (PPP3R2)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    5535 (PPP3R2)
   04660 T cell receptor signaling pathway
    5535 (PPP3R2)
   04662 B cell receptor signaling pathway
    5535 (PPP3R2)
  Endocrine system
   04921 Oxytocin signaling pathway
    5535 (PPP3R2)
  Nervous system
   04724 Glutamatergic synapse
    5535 (PPP3R2)
   04720 Long-term potentiation
    5535 (PPP3R2)
  Development
   04360 Axon guidance
    5535 (PPP3R2)
   04380 Osteoclast differentiation
    5535 (PPP3R2)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    5535 (PPP3R2)
   05014 Amyotrophic lateral sclerosis (ALS)
    5535 (PPP3R2)
  Substance dependence
   05031 Amphetamine addiction
    5535 (PPP3R2)
  Infectious diseases
   05152 Tuberculosis
    5535 (PPP3R2)
   05166 HTLV-I infection
    5535 (PPP3R2)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     5535 (PPP3R2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
9q31.1
AA seq 173 aa AA seqDB search
MSTMGNEASYPAEMCSHFDNDEIKRLGRRFKKLDLDKSGSLSVEEFMSLPELRHNPLVRR
VIDVFDTDGDGEVDFKEFILGTSQFSVKGDEEQKLRFAFSIYDMDKDGYISNGELFQVLK
MMVGNNLTDWQLQQLVDKTIIILDKDGDGKISFEEFSAVVRDLEIHKKLVLIV
NT seq 522 nt NT seq  +upstreamnt  +downstreamnt
atgtccacaatgggaaacgaggccagttacccggcggagatgtgctcccactttgacaat
gatgaaattaaaaggctgggcaggaggtttaagaagttggacttggacaaatcagggtct
ctgagcgtggaggagttcatgtccctgccggagctgcgccacaacccgttggtgcggcga
gtgatcgacgtcttcgacaccgacggtgatggagaagtggacttcaaggaattcatcctg
gggacctcccagttcagcgtcaagggcgacgaggagcagaagttgaggtttgcgttcagc
atttacgacatggataaagatggctacatttccaacggggagctcttccaggtgctgaag
atgatggtgggcaacaacctgacggactggcagctccagcagctggtcgacaaaaccatc
atcatcctggacaaggatggcgatgggaagatatcctttgaggaattcagtgctgtggtc
agagacctggagatccacaagaagctggtcctcatcgtatga

DBGET integrated database retrieval system