KEGG   Homo sapiens (human): 5565Help
Entry
5565              CDS       T01001                                 

Gene name
PRKAB2
Definition
(RefSeq) protein kinase AMP-activated non-catalytic subunit beta 2
  KO
K07199  5'-AMP-activated protein kinase, regulatory beta subunit
Organism
hsa  Homo sapiens (human)
Pathway
hsa04068  FoxO signaling pathway
hsa04152  AMPK signaling pathway
hsa04211  Longevity regulating pathway
hsa04213  Longevity regulating pathway - multiple species
hsa04371  Apelin signaling pathway
hsa04530  Tight junction
hsa04710  Circadian rhythm
hsa04714  Thermogenesis
hsa04910  Insulin signaling pathway
hsa04920  Adipocytokine signaling pathway
hsa04921  Oxytocin signaling pathway
hsa04922  Glucagon signaling pathway
hsa04931  Insulin resistance
hsa04932  Non-alcoholic fatty liver disease (NAFLD)
hsa05410  Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04371 Apelin signaling pathway
    5565 (PRKAB2)
   04068 FoxO signaling pathway
    5565 (PRKAB2)
   04152 AMPK signaling pathway
    5565 (PRKAB2)
 Cellular Processes
  Cellular community - eukaryotes
   04530 Tight junction
    5565 (PRKAB2)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    5565 (PRKAB2)
   04922 Glucagon signaling pathway
    5565 (PRKAB2)
   04920 Adipocytokine signaling pathway
    5565 (PRKAB2)
   04921 Oxytocin signaling pathway
    5565 (PRKAB2)
  Aging
   04211 Longevity regulating pathway - mammal
    5565 (PRKAB2)
   04213 Longevity regulating pathway - multiple species
    5565 (PRKAB2)
  Environmental adaptation
   04710 Circadian rhythm
    5565 (PRKAB2)
   04714 Thermogenesis
    5565 (PRKAB2)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    5565 (PRKAB2)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    5565 (PRKAB2)
   04931 Insulin resistance
    5565 (PRKAB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: AMPK1_CBM AMPKBI CBM_48
Motif
Other DBs
NCBI-GeneID: 5565
NCBI-ProteinID: NP_005390
OMIM: 602741
HGNC: 9379
Ensembl: ENSG00000131791
Vega: OTTHUMG00000014032
Pharos: O43741(Tbio)
UniProt: O43741
Structure
PDB: 

Jmol
Position
1q21.1
AA seq 272 aa AA seqDB search
MGNTTSDRVSGERHGAKAARSEGAGGHAPGKEHKIMVGSTDDPSVFSLPDSKLPGDKEFV
SWQQDLEDSVKPTQQARPTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAILDLPE
GEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFEVFDALKLDSMESSETSCRD
LSSSPPGPYGQEMYAFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNH
LYALSIKDSVMVLSATHRYKKKYVTTLLYKPI
NT seq 819 nt NT seq  +upstreamnt  +downstreamnt
atgggaaacaccaccagcgaccgggtgtccggggagcgccacggcgccaaggctgcacgc
tccgagggcgcaggcggccatgccccggggaaggagcacaagatcatggtggggagtacg
gacgaccccagcgtgttcagcctccctgactccaagctccctggggacaaagagtttgta
tcatggcagcaggatttggaggactccgtaaagcccacacagcaggcccggcccactgtt
atccgctggtctgaaggaggcaaggaggtcttcatctctgggtccttcaacaattggagc
accaagattccactgattaagagccataatgactttgttgccatcctggacctccctgag
ggagagcaccaatacaagttctttgtggatggacagtgggttcatgatccatcagagcct
gtggttaccagtcagcttggcacaattaacaatttgatccatgtcaagaaatctgatttt
gaggtgttcgatgctttaaagttagattctatggaaagttctgagacatcttgtagagac
ctttccagctcacccccagggccttatggtcaagaaatgtatgcgtttcgatctgaggaa
agattcaaatccccacccatccttcctcctcatctacttcaagttattcttaacaaagac
actaatatttcttgtgacccagccttactccctgagcccaaccatgttatgctgaaccat
ctctatgcattgtccattaaggacagtgtgatggtccttagcgcaacccatcgctacaag
aagaagtatgttactactctgctatacaagcccatttga

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