KEGG   Homo sapiens (human): 5585Help
Entry
5585              CDS       T01001                                 

Gene name
PKN1, DBK, PAK-1, PAK1, PKN, PKN-ALPHA, PRK1, PRKCL1
Definition
(RefSeq) protein kinase N1 (EC:2.7.11.13)
  KO
K06071  
protein kinase N [EC:2.7.11.13]
Organism
hsa  Homo sapiens (human)
Pathway
PI3K-Akt signaling pathway
Salmonella infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    5585 (PKN1)
 Human Diseases
  Infectious diseases
   05132 Salmonella infection
    5585 (PKN1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     5585 (PKN1)
Protein kinases [BR:hsa01001]
 Serine/threonine protein kinases: AGC group
  PKN family
   5585 (PKN1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
19p13.12
AA seq 942 aa AA seqDB search
MASDAVQSEPRSWSLLEQLGLAGADLAAPGVQQQLELERERLRREIRKELKLKEGAENLR
RATTDLGRSLGPVELLLRGSSRRLDLLHQQLQELHAHVVLPDPAATHDGPQSPGAGGPTC
SATNLSRVAGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLTAQQMLQDSKTKIDII
RMQLRRALQAGQLENQAAPDDTQGSPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLS
AAKAPDRKAVSEAQEKLTESNQKLGLLREALERRLGELPADHPKGRLLREELAAASSAAF
STRLAGPFPATHYSTLCKPAPLTGTLEVRVVGCRDLPETIPWNPTPSMGGPGTPDSRPPF
LSRPARGLYSRSGSLSGRSSLKAEAENTSEVSTVLKLDNTVVGQTSWKPCGPNAWDQSFT
LELERARELELAVFWRDQRGLCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPV
IERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRLIPNATGTGTFSPGASPGS
EARTTGDISVEKLNLGTDSDSSPQKSSRDPPSSPSSLSSPIQESTAPELPSETQETPGPA
LCSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESL
MCEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAIFY
SACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPE
FLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSA
EAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTD
VSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFLDFDFVAGGC
NT seq 2829 nt NT seq  +upstreamnt  +downstreamnt
atggccagcgacgccgtgcagagtgagcctcgcagctggtccctgctagagcagctgggc
ctggccggggcagacctggcggcccccggggtacagcagcagctggagctggagcgggag
cggctgcggcgggaaatccgcaaggagctgaagctgaaggagggtgctgagaacctgcgg
cgggccaccactgacctgggccgcagcctgggccccgtagagctgctgctgcggggctcc
tcgcgccgcctcgacctgctgcaccagcagctgcaggagctgcacgcccacgtggtgctt
cccgacccggcggccacccacgatggcccccagtcccctggtgcgggtggccccacctgc
tcggccaccaacctgagccgcgtggcgggcctggagaagcagttggccattgagctgaag
gtgaagcagggggcggagaacatgatccagacctacagcaatggcagcaccaaggaccgg
aagctgctgctgacagcccagcagatgttgcaggacagtaagaccaagattgacatcatc
cgcatgcaactccgccgggcgctgcaggccggccagctggagaaccaggcagccccggat
gacacccaagggagtcctgacctgggggctgtggagctgcgcatcgaagagctgcggcac
cacttccgagtggagcacgcggtggccgagggtgccaagaacgtactgcgcctgctcagc
gctgccaaggccccggaccgcaaggcagtcagcgaggcccaggagaaattgacagaatcc
aaccagaagctggggctgctgcgggaggctctggagcggagacttggggagctgcccgcc
gaccaccccaaggggcggctgctgcgagaagagctcgctgcggcctcctccgctgccttc
agcacccgcctggccgggccctttcccgccacgcactacagcaccctgtgcaagcccgcg
ccgctcacagggaccctggaggtacgagtggtgggctgcagagacctcccagagaccatc
ccgtggaaccctaccccctcaatggggggacctgggaccccagacagccgcccccccttc
ctgagccgcccagcccggggcctttacagccgaagcggaagcctcagtggccggagcagc
ctcaaagcagaagccgagaacaccagtgaagtcagcactgtgcttaagctggataacaca
gtggtggggcagacgtcttggaagccatgtggccccaatgcctgggaccagagcttcact
ctggagctggaaagggcacgggaactggagttggctgtgttctggcgggaccagcggggc
ctgtgtgccctcaaattcctgaagttggaggatttcttggacaatgagaggcatgaggtg
cagctggacatggaaccccagggctgcctggtggctgaggtcaccttccgcaaccctgtc
attgagaggattcctcggctccgacggcagaagaaaattttctccaagcagcaagggaag
gcgttccagcgtgctaggcagatgaacatcgatgtcgccacgtgggtgcggctgctccgg
aggctcatccccaatgccacgggcacaggcacctttagccctggggcttctccaggatcc
gaggcccggaccacgggtgacatatcggtggagaagctgaacctcggcactgactcggac
agctcacctcagaagagctcgcgggatcctccttccagcccatcgagcctgagctccccc
atccaggaatccactgctcccgagctgccttcggagacccaggagaccccaggccccgcc
ctgtgcagccctctgaggaagtcacctctgaccctcgaagatttcaagttcctggcggtg
ctgggccggggtcattttgggaaggtgctcctctccgaattccggcccagtggggagctg
ttcgccatcaaggctctgaagaaaggggacattgtggcccgagacgaggtggagagcctg
atgtgtgagaagcggatattggcggcagtgaccagtgcgggacaccccttcctggtgaac
ctcttcggctgtttccagacaccggagcacgtgtgcttcgtgatggagtactcggccggt
ggggacctgatgctgcacatccacagcgacgtgttctctgagccccgtgccatcttttat
tccgcctgcgtggtgctgggcctacagtttcttcacgaacacaagatcgtctacagggac
ctgaagttggacaatttgctcctggacaccgagggctacgtcaagatcgcagactttggc
ctctgcaaggaggggatgggctatggggaccggaccagcacattctgtgggaccccggag
ttcctggcccctgaggtgctgacggacacgtcgtacacgcgagctgtggactggtgggga
ctgggtgtgctgctctacgagatgctggttggcgagtccccattcccaggggatgatgag
gaggaggtcttcgacagcatcgtcaacgacgaggttcgctacccccgcttcctgtcggcc
gaagccatcggcatcatgagaaggctgcttcggaggaacccagagcggaggctgggatct
agcgagagagatgcagaagatgtgaagaaacagcccttcttcaggactctgggctgggaa
gccctgttggcccggcgcctgccaccgccctttgtgcccacgctgtccggccgcaccgac
gtcagcaacttcgacgaggagttcaccggggaggcccccacactgagcccgccccgcgac
gcgcggcccctcacagccgcggagcaggcagccttcctggacttcgacttcgtggccggg
ggctgctag

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