KEGG   Homo sapiens (human): 5689Help
Entry
5689              CDS       T01001                                 

Gene name
PSMB1, HC5, PMSB1, PSC5
Definition
(RefSeq) proteasome subunit beta 1
  KO
K02732  20S proteasome subunit beta 6 [EC:3.4.25.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03050  Proteasome
Module
hsa_M00337  Immunoproteasome
hsa_M00340  Proteasome, 20S core particle
Drug target
Delanzomib: D10110
Marizomib: D09640
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Genetic Information Processing
  Folding, sorting and degradation
   03050 Proteasome
    5689 (PSMB1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.25  Threonine endopeptidases
    3.4.25.1  proteasome endopeptidase complex
     5689 (PSMB1)
Peptidases [BR:hsa01002]
 Threonine Peptidases
  Family T1: proteasome family
   5689 (PSMB1)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Core particles (20S proteasome)
   beta type subunits
    5689 (PSMB1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Proteasome Cytochrom_C1
Motif
Other DBs
NCBI-GeneID: 5689
NCBI-ProteinID: NP_002784
OMIM: 602017
HGNC: 9537
Ensembl: ENSG00000008018
Vega: OTTHUMG00000016087
Pharos: P20618(Tclin)
UniProt: P20618 A0A140VK45
Structure
PDB: 

Jmol
Position
6q27
AA seq 241 aa AA seqDB search
MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEG
FSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAML
STILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQ
VGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRK
D
NT seq 726 nt NT seq  +upstreamnt  +downstreamnt
atgttgtcctctacagccatgtattcggctcctggcagagacttggggatggaaccgcac
agagccgcgggccctttgcagctgcgattttcgccctacgttttcaacggaggtactata
ctggcaattgctggagaagattttgcaattgttgcttctgatactcgattgagtgaaggg
ttttcaattcatacgcgggatagccccaaatgttacaaattaacagacaaaacagtcatt
ggatgcagcggttttcatggagactgtcttacgctgacaaagattattgaagcaagacta
aagatgtataagcattccaataataaggccatgactacgggggcaattgctgcaatgctg
tctacaatcctgtattcaaggcgcttctttccatactatgtttacaacatcatcggtgga
cttgatgaagaaggaaagggggctgtatacagctttgatccagtagggtcttaccagaga
gactccttcaaggctggaggctcagcaagtgccatgctacagcccctgcttgacaaccag
gttggttttaagaacatgcagaatgtggagcatgttccgctgtccttggacagagccatg
cggctggtgaaagatgtcttcatttctgcggctgagagagatgtgtacactggggacgca
ctccggatctgcatagtgaccaaagagggcatcagggaggaaactgtttccttaaggaag
gactga

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