KEGG   Homo sapiens (human): 57412
Entry
57412             CDS       T01001                                 
Symbol
AS3MT, CYT19
Name
(RefSeq) arsenite methyltransferase
  KO
K07755  arsenite methyltransferase [EC:2.1.1.137]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05208  Chemical carcinogenesis - reactive oxygen species
Network
nt06252  Mitochondrial ROS formation (cancer)
  Element
N01392  Arsenic to electron transfer in complex II
N01393  Arsenic to electron transfer in complex II
N01394  Arsenic to electron transfer in complex IV
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    57412 (AS3MT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.137  arsenite methyltransferase
     57412 (AS3MT)
SSDB
Motif
Pfam: Methyltransf_31 Methyltransf_11 Methyltransf_25 Ubie_methyltran Methyltransf_12 Methyltransf_23 PCMT Methyltransf_8 Anamorsin_N DOT1 FtsJ PrmA MTS Methyltransf_33 TehB
Other DBs
NCBI-GeneID: 57412
NCBI-ProteinID: NP_065733
OMIM: 611806
HGNC: 17452
Ensembl: ENSG00000214435
UniProt: Q9HBK9
Position
10:102869470..102901899
AA seq 375 aa
MAALRDAEIQKDVQTYYGQVLKRSADLQTNGCVTTARPVPKHIREALQNVHEEVALRYYG
CGLVIPEHLENCWILDLGSGSGRDCYVLSQLVGEKGHVTGIDMTKGQVEVAEKYLDYHME
KYGFQASNVTFIHGYIEKLGEAGIKNESHDIVVSNCVINLVPDKQQVLQEAYRVLKHGGE
LYFSDVYTSLELPEEIRTHKVLWGECLGGALYWKELAVLAQKIGFCPPRLVTANLITIQN
KELERVIGDCRFVSATFRLFKHSKTGPTKRCQVIYNGGITGHEKELMFDANFTFKEGEIV
EVDEETAAILKNSRFAQDFLIRPIGEKLPTSGGCSALELKDIITDPFKLAEESDSMKSRC
VPDAAGGCCGTKKSC
NT seq 1128 nt   +upstreamnt  +downstreamnt
atggctgcacttcgtgacgctgagatacagaaggacgtgcagacctactacgggcaggtg
ctgaagagatcggcagacctccagaccaacggctgtgtcaccacagccaggccggtcccc
aagcacatccgggaagccttgcaaaatgtacacgaagaagtagccctaagatattatggc
tgtggtctggtgatccctgagcatctagaaaactgctggattttggatctgggtagtgga
agtggcagagattgctatgtacttagccagctggttggtgaaaaaggacacgtgactgga
atagacatgaccaaaggccaggtggaagtggctgaaaagtatcttgactatcacatggaa
aaatatggcttccaggcatctaatgtgacttttattcatggctacattgagaagttggga
gaggctggaatcaagaatgagagccatgatattgttgtatcaaactgtgttattaacctt
gtgcctgataaacaacaagtgcttcaggaggcatatcgggtgctgaagcatggtggggag
ttatatttcagtgacgtctatacgagccttgaactgccagaagaaatcaggacacacaaa
gttttatggggtgagtgtctgggtggtgctttatactggaaggaacttgctgtccttgct
caaaaaattgggttctgccctccacgtttggtcactgccaatctcattacaattcaaaac
aaggaactggaaagagttatcggtgactgtcgttttgtttctgcaacatttcgcctcttc
aaacactctaagacaggaccaaccaagagatgccaagttatttacaatggaggaattaca
ggacatgaaaaagaactaatgtttgatgccaattttacatttaaggaaggtgaaattgtt
gaagtggatgaagaaacagcagctatcttgaagaattcaagatttgctcaagattttctg
atcagaccaattggagagaagttgccaacatctggaggctgttctgctttggagttaaag
gatataatcacagatccatttaagcttgcagaagagtctgacagtatgaagtccagatgt
gtccctgatgctgctggaggctgctgtggcacaaagaaaagctgctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (4)   
   KEGG NETWORK (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (15)   
   Pfam (15)   
All databases (55)   

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