KEGG   Homo sapiens (human): 5787
Entry
5787              CDS       T01001                                 
Symbol
PTPRB, HPTP-BETA, HPTPB, PTPB, R-PTP-BETA, VEPTP
Name
(RefSeq) protein tyrosine phosphatase receptor type B
  KO
K05694  receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    5787 (PTPRB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5787 (PTPRB)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     5787 (PTPRB)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Receptor PTPs
    5787 (PTPRB)
SSDB
Motif
Pfam: fn3 Y_phosphatase PTP_tm Glyco_hydro_66 DSPc Y_phosphatase3 PTPlike_phytase
Other DBs
NCBI-GeneID: 5787
NCBI-ProteinID: NP_002828
OMIM: 176882
HGNC: 9665
Ensembl: ENSG00000127329
UniProt: P23467
Structure
Position
12:complement(70515870..70637429)
AA seq 1997 aa
MLSHGAGLALWITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSS
DTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVSK
EKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYN
IAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG
ILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTND
GSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSC
VSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLL
NITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANE
TSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISG
DLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNES
ISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYL
SVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYE
NHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPK
SENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWS
GANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAF
IEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFE
HTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAA
GVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTE
GRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFS
FQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGD
FDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTA
PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVY
GLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDS
DFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDS
TITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDE
LKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCD
PTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAI
EGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTS
CPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYD
ATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVM
VTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLI
RHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRI
LQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPI
YENVNPEYHRDPVYSRH
NT seq 5994 nt   +upstreamnt  +downstreamnt
atgctgagccatggagccgggttggccttgtggatcacactgagcctgctgcagactgga
ctggcggagccagagagatgtaacttcaccctggcggagtccaaggcctccagccattct
gtgtctatccagtggagaattttgggctcaccctgtaactttagcctcatctatagcagt
gacaccctgggggccgcgttgtgccctacctttcggatagacaacaccacatacggatgt
aaccttcaagatttacaagcaggaaccatctataacttcaggattatttctctggatgaa
gagagaacagtggtcttgcaaacagatcctttacctcctgctaggtttggagtcagtaaa
gagaagacgacttcaaccagcttgcatgtttggtggactccttcttccggaaaagtcacc
tcatatgaggtgcaattatttgatgaaaataaccaaaagatacagggggttcaaattcaa
gaaagtacttcatggaatgaatacacttttttcaatctcactgctggtagtaaatacaat
attgccatcacagctgtttctggaggaaaacgttctttttcagtttataccaatggatca
acagtgccatctccagtgaaagatattggtatttccacaaaagccaattctctcctgatt
tcctggtcccatggttctgggaatgtggaacgataccggctgatgctaatggataaaggg
atcctagttcatggcggtgttgtggacaaacatgctacttcctatgcttttcacgggctg
acccctggctacctctacaacctcactgttatgactgaggctgcagggctgcaaaactac
aggtggaaactagtcaggacagcccccatggaagtctcaaatctgaaggtgacaaatgat
ggcagtttgacctctctaaaagtcaaatggcaaagacctcctggaaatgtggattcttac
aatatcaccctgtctcacaaagggaccatcaaggaatccagagtattagcaccttggatt
actgaaactcactttaaagagttagtccccggtcgactttatcaagttactgtcagctgt
gtctctggtgaactgtctgctcagaagatggcagtgggcagaacatttccagacaaagtt
gcaaacctggaggcaaacaataatggcaggatgaggtctcttgtagtgagctggtcgccc
cctgctggagactgggagcagtatcggatcctactcttcaatgattctgtggtgctgctc
aacatcactgtgggaaaggaagaaacacagtatgtcatggatgacacggggctcgtaccg
ggaagacagtatgaggtggaagtcattgttgagagtggaaatttgaagaattctgagcgt
tgccaaggcaggacagtccccctggctgtcctccagcttcgtgtcaaacatgccaatgaa
acctcactgagtatcatgtggcagacccctgtagcagaatgggagaaatacatcatttcc
ctagctgacagagacctcttactgatccacaagtcactctccaaagatgccaaagaattc
acttttactgacctggtgcctggacgaaaatacatggctacagtcaccagtattagtgga
gacttaaaaaattcctcttcagtaaaaggaagaacagtgcctgcccaagtgactgacttg
catgtggccaaccaaggaatgaccagtagtctgtttactaactggacccaggcacaagga
gacgtagaattttaccaagtcttactgatccatgaaaatgtggtcattaaaaatgaaagc
atctccagtgagaccagcagatacagcttccactctctcaagtccggcagcctgtactcc
gtggtggtaacaacagtgagtggagggatctcttcccgacaagtggttgtggagggaaga
acagtcccttccagtgtgagtggagtaacggtgaacaattccggtcgtaatgactacctc
agcgtttcctggctgctggcgcccggagatgtggataactatgaggtaacattgtctcat
gacggcaaggtggttcagtcccttgtcattgccaagtctgtcagagaatgttccttcagc
tccctcaccccaggccgcctctacaccgtgaccataactacaaggagtggcaagtatgaa
aatcactccttcagccaagagcggacagtgcctgacaaagtccagggagtcagtgttagc
aactcagccaggagtgactatttaagggtatcctgggtgcatgccactggagactttgat
cactatgaagtcaccattaaaaacaaaaacaacttcattcaaactaaaagcattcccaag
tcagaaaacgaatgtgtatttgttcagctagtccctggacggttgtacagtgtcactgtt
actacaaaaagtggacaatatgaagccaatgaacaagggaatgggagaacaattccagag
cctgttaaggatctaacattgcgcaacaggagcactgaggacttgcatgtgacttggtca
ggagctaatggggatgtcgaccaatatgagatccagctgctcttcaatgacatgaaagta
tttcctccttttcaccttgtaaataccgcaaccgagtatcgatttacttccctaacacca
ggccgccaatacaaaattcttgtcttgacgattagcggggatgtacagcagtcagccttc
attgagggcttcacagttcctagtgctgtcaaaaatattcacatttctcccaatggagca
acagatagcctgacggtgaactggactcctggtgggggagacgttgattcctacacggtg
tcggcattcaggcacagtcaaaaggttgactctcagactattcccaagcacgtctttgag
cacacgttccacagactggaggccggggagcagtaccagatcatgattgcctcagtcagc
gggtccctgaagaatcagataaatgtggttgggcggacagttccagcatctgtccaagga
gtaattgcagacaatgcatacagcagttattccttaatagtaagttggcaaaaagctgct
ggtgtggcagaaagatatgatatcctgcttctaactgaaaatggaatccttctgcgcaac
acatcagagccagccaccactaagcaacacaaatttgaagatctaacaccaggcaagaaa
tacaagatacagatcctaactgtcagtggaggcctctttagcaaggaagcccagactgaa
ggccgaacagtcccagcagctgtcaccgacctgaggatcacagagaactccaccaggcac
ctgtccttccgctggaccgcctcagagggggagctcagctggtacaacatctttttgtac
aacccagatgggaatctccaggagagagctcaagttgacccactagtccagagcttctct
ttccagaacttgctacaaggcagaatgtacaagatggtgattgtaactcacagtggggag
ctgtctaatgagtctttcatatttggtagaacagtcccagcctctgtgagtcatctcagg
gggtccaatcggaacacgacagacagcctttggttcaactggagtccagcctctggggac
tttgacttttatgagctgattctctataatcccaatggcacaaagaaggaaaactggaaa
gacaaggacctgacggagtggcggtttcaaggccttgttcctggaaggaagtacgtgctg
tgggtggtaactcacagtggagatctcagcaataaagtcacagcggagagcagaacagct
ccaagtcctcccagtcttatgtcatttgctgacattgcaaacacatccttggccatcacg
tggaaagggcccccagactggacagactacaacgactttgagctgcagtggttgcccaga
gatgcacttactgtcttcaacccctacaacaacagaaaatcagaaggacgcattgtgtat
ggtcttcgtccagggagatcctatcaattcaacgtcaagactgtcagtggtgattcctgg
aaaacttacagcaaaccaatttttggatctgtgaggacaaagcctgacaagatacaaaac
ctgcattgccggcctcagaactccacggccattgcctgttcttggatccctcctgattct
gactttgatggttatagtattgaatgccggaaaatggacacccaagaagttgagttttcc
agaaagctggagaaagaaaaatctctgctcaacatcatgatgctagtgccccataagagg
tacctggtgtccatcaaagtgcagtcggccggcatgaccagcgaggtggttgaagacagc
actatcacaatgatagaccgcccccctcctccacccccacacattcgtgtgaatgaaaag
gatgtgctaattagcaagtcttccatcaactttactgtcaactgcagctggttcagcgac
accaatggagctgtgaaatacttcacagtggtggtgagagaggctgatggcagtgatgag
ctgaagccagaacagcagcaccctctcccttcctacctggagtacaggcacaatgcctcc
attcgggtgtatcagactaattattttgccagcaaatgtgccgaaaatcctaacagcaac
tccaagagttttaacattaagcttggagcagagatggagagcctaggtggaaaatgcgat
cccactcagcaaaaattctgtgatggaccactgaagccacacactgcctacagaatcagc
attcgagcttttacacagctctttgatgaggacctgaaggaattcacaaagccactctat
tcagacacatttttttctttacccatcactactgaatcagagcccttgtttggagctatt
gaaggtgtgagtgctggtctgtttttaattggcatgctagtggctgttgttgccttattg
atctgcagacagaaagtgagccatggtcgagaaagaccctctgcccgtctgagcattcgt
agggatcgaccattatctgtccacttaaacctgggccagaaaggtaaccggaaaacttct
tgtccaataaaaataaatcagtttgaagggcatttcatgaagctacaggctgactccaac
taccttctatccaaggaatacgaggagttaaaagacgtgggccgaaaccagtcatgtgac
attgcactcttgccggagaatagagggaaaaatcgatacaacaatatattgccctatgat
gccacgcgagtgaagctctccaatgtagatgatgatccttgctctgactacatcaatgcc
agctacatccctggcaacaacttcagaagagaatacattgtcactcagggaccgcttcct
ggcaccaaggatgacttctggaaaatggtgtgggaacaaaacgttcacaacatcgtcatg
gtgacccagtgtgttgagaagggccgagtaaagtgtgatcattactggccagcggaccag
gattccctctactatggggacctcatcctgcagatgctctcagagtccgtcctgcctgag
tggaccatccgggagtttaagatatgcggtgaggaacagcttgatgcacacagactcatc
cgccactttcactatacggtgtggccagaccatggagtcccagaaaccacccagtctctg
atccagtttgtgagaactgtcagggactacatcaacagaagcccgggtgctgggcccact
gtggtgcactgcagtgctggtgtgggtaggactggaacctttattgcattggaccgaatc
ctccagcagttagactccaaagactctgtggacatttatggagcagtgcacgacctaaga
cttcacagggttcacatggtccagactgagtgtcagtatgtctacctacatcagtgtgta
agagatgtcctcagagcaagaaagctacggagtgaacaagaaaaccccttgtttccaatc
tatgaaaatgtgaatccagagtatcacagagatccagtctattcaaggcattga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (15)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (57)   
   RefSeq(nuc) (15)   
   GenBank (21)   
   EMBL (21)   
3D Structure (12)   
   PDB (12)   
Protein domain (7)   
   Pfam (7)   
All databases (121)   

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