KEGG   Homo sapiens (human): 5798
Entry
5798              CDS       T01001                                 
Symbol
PTPRN, IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Name
(RefSeq) protein tyrosine phosphatase receptor type N
  KO
K07817  receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04940  Type I diabetes mellitus
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    5798 (PTPRN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5798 (PTPRN)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     5798 (PTPRN)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Receptor PTPs
    5798 (PTPRN)
SSDB
Motif
Pfam: Y_phosphatase Receptor_IA-2 RESP18 DSPc
Other DBs
NCBI-GeneID: 5798
NCBI-ProteinID: NP_002837
OMIM: 601773
HGNC: 9676
Ensembl: ENSG00000054356
UniProt: Q16849 Q96IA0
Structure
Position
2:complement(219289623..219309401)
AA seq 979 aa
MRRPRRPGGLGGSGGLRLLLCLLLLSSRPGGCSAVSAHGCLFDRRLCSHLEVCIQDGLFG
QCQVGVGQARPLLQVTSPVLQRLQGVLRQLMSQGLSWHDDLTQYVISQEMERIPRLRPPE
PRPRDRSGLAPKRPGPAGELLLQDIPTGSAPAAQHRLPQPPVGKGGAGASSSLSPLQAEL
LPPLLEHLLLPPQPPHPSLSYEPALLQPYLFHQFGSRDGSRVSEGSPGMVSVGPLPKAEA
PALFSRTASKGIFGDHPGHSYGDLPGPSPAQLFQDSGLLYLAQELPAPSRARVPRLPEQG
SSSRAEDSPEGYEKEGLGDRGEKPASPAVQPDAALQRLAAVLAGYGVELRQLTPEQLSTL
LTLLQLLPKGAGRNPGGVVNVGADIKKTMEGPVEGRDTAELPARTSPMPGHPTASPTSSE
VQQVPSPVSSEPPKAARPPVTPVLLEKKSPLGQSQPTVAGQPSARPAAEEYGYIVTDQKP
LSLAAGVKLLEILAEHVHMSSGSFINISVVGPALTFRIRHNEQNLSLADVTQQAGLVKSE
LEAQTGLQILQTGVGQREEAAAVLPQTAHSTSPMRSVLLTLVALAGVAGLLVALAVALCV
RQHARQQDKERLAALGPEGAHGDTTFEYQDLCRQHMATKSLFNRAEGPPEPSRVSSVSSQ
FSDAAQASPSSHSSTPSWCEEPAQANMDISTGHMILAYMEDHLRNRDRLAKEWQALCAYQ
AEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMPAY
IATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGASLYHVYEVNLV
SEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRG
RSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFE
FALTAVAEEVNAILKALPQ
NT seq 2940 nt   +upstreamnt  +downstreamnt
atgcggcgcccgcggcggcctgggggtctcgggggatccgggggtctccggctgctcctc
tgcctcctgctgctgagcagccgcccggggggctgcagcgccgttagtgcccacggctgt
ctatttgaccgcaggctctgctctcacctggaagtctgtattcaggatggcttgtttggg
cagtgccaggtgggagtggggcaggcccggccccttttgcaagtcacctccccagttctc
caacgcttacaaggtgtgctccgacaactcatgtcccaaggattgtcctggcacgatgac
ctcacccagtatgtgatctctcaggagatggagcgcatccccaggcttcgccccccagag
ccccgtccaagggacaggtctggcttggcacccaagagacctggtcctgctggagagctg
cttttacaggacatccccactggctccgcccctgctgcccagcatcggcttccacaacca
ccagtgggcaaaggtggagctggggccagctcctctctgtcccctctgcaggctgagctg
ctcccgcctctcttggagcacctgctgctgcccccacagcctccccacccttcactgagt
tacgaacctgccttgctgcagccctacctgttccaccagtttggctcccgtgatggctcc
agggtctcagagggctccccagggatggtcagtgtcggccccctgcccaaggctgaagcc
cctgccctcttcagcagaactgcctccaagggcatatttggggaccaccctggccactcc
tacggggaccttccagggccttcacctgcccagctttttcaagactctgggctgctctat
ctggcccaggagttgccagcacccagcagggccagggtgccaaggctgccagagcaaggg
agcagcagccgggcagaggactccccagagggctatgagaaggaaggactaggggatcgt
ggagagaagcctgcttccccagctgtgcagccagatgcggctctgcagaggctggccgct
gtgctggcgggctatggggtagagctgcgtcagctgacccctgagcagctctccacactc
ctgaccctgctgcagctactgcccaagggtgcaggaagaaatccgggaggggttgtaaat
gttggagctgatatcaagaaaacaatggaggggccggtggagggcagagacacagcagag
cttccagcccgcacatcccccatgcctggacaccccactgccagccctacctccagtgaa
gtccagcaggtgccaagccctgtctcctctgagcctcccaaagctgccagaccccctgtg
acacctgtcctgctagagaagaaaagcccactgggccagagccagcccacggtggcagga
cagccctcagcccgcccagcagcagaggaatatggctacatcgtcactgatcagaagccc
ctgagcctggctgcaggagtgaagctgctggagatcctggctgagcatgtgcacatgtcc
tcaggcagcttcatcaacatcagtgtggtgggaccagccctcaccttccgcatccggcac
aatgagcagaacctgtctttggctgatgtgacccaacaagcagggctggtgaagtctgaa
ctggaagcacagacagggctccaaatcttgcagacaggagtgggacagagggaggaggca
gctgcagtccttccccaaactgcgcacagcacctcacccatgcgctcagtgctgctcact
ctggtggccctggcaggtgtggctgggctgctggtggctctggctgtggctctgtgtgtg
cggcagcatgcgcggcagcaagacaaggagcgcctggcagccctggggcctgagggggcc
catggtgacactacctttgagtaccaggacctgtgccgccagcacatggccacgaagtcc
ttgttcaaccgggcagagggtccaccggagccttcacgggtgagcagtgtgtcctcccag
ttcagcgacgcagcccaggccagccccagctcccacagcagcaccccgtcctggtgcgag
gagccggcccaagccaacatggacatctccacgggacacatgattctggcatacatggag
gatcacctgcggaaccgggaccgccttgccaaggagtggcaggccctctgtgcctaccaa
gcagagccaaacacctgtgccaccgcgcagggggagggcaacatcaaaaagaaccggcat
cctgacttcctgccctatgaccatgcccgcataaaactgaaggtggagagcagcccttct
cggagcgattacatcaacgccagccccattattgagcatgaccctcggatgccagcctac
atagccacgcagggcccgctgtcccataccatcgcagacttctggcagatggtgtgggag
agcggctgcaccgtcatcgtcatgctgaccccgctggtggaggatggtgtcaagcagtgt
gaccgctactggccagatgagggtgcctccctctaccacgtatatgaggtgaacctggtg
tcggagcacatctggtgcgaggactttctggtgcggagcttctacctgaagaacgtgcag
acccaggagacgcgcacgctcacgcagttccacttcctcagctggccggcagagggcaca
ccggcctccacgcggcccctgctggacttccgcaggaaggtgaacaagtgctaccggggc
cgctcctgccccatcatcgtgcactgcagtgatggtgcggggaggaccggcacctacatc
ctcatcgacatggtcctgaaccgcatggcaaaaggagtgaaggagattgacatcgctgcc
accctggagcatgtccgtgaccagcggcctggccttgtccgctctaaggaccagtttgaa
tttgccctgacagccgtggcggaggaagtgaatgccatcctcaaggccctgccccagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (33)   
   RefSeq(nuc) (3)   
   GenBank (15)   
   EMBL (15)   
3D Structure (6)   
   PDB (6)   
Protein domain (4)   
   Pfam (4)   
All databases (78)   

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