KEGG T01001: 5923

Homo sapiens (human): 5923

Entry

5923 CDS T01001

Gene name

RASGRF1, CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1

Definition

Ras protein-specific guanine nucleotide-releasing factor 1

Orthology

K04349

Ras-specific guanine nucleotide-releasing factor 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04010	MAPK signaling pathway
hsa04510	Focal adhesion

Class

Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:hsa04010]
Cellular Processes; Cell communication; Focal adhesion [PATH:hsa04510]

SSDB

Motif

Pfam:

RasGEF RhoGEF PH RasGEF_N PH_11 IQ

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

Ensembl:

Vega:

UniProt:

Q13972 A8K270 F8VPA5 J3KQP9 Q8IUU5

Position

15q24.2

AA seq 1257 aa
MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
KVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNT
FLHSYRVFTTAIVVLDKLITIYKKPISAIPARSLELLFASGQNNKLLYGEPPKSPRATRK
FSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSPFSKAT
LDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESDIDQNQSDDGDTET
SPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGANEG
TPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETNDELK
CKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEITQMAEGVKAEPFEN
HSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASE
IIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTK
ALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLVNFS
KMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPKLPT

NT seq 3774 nt +upstreamnt +downstreamnt
atgcagaaggggatccggctgaatgatggccacgtcgcgtccctgggactgctggcgcgc
aaggacggcacgcgcaaaggctacctgagcaagcggagttcggacaacacaaaatggcaa
accaagtggttcgcgctgctgcagaacctgctcttctacttcgagagcgactcgagctcg
cggccctcggggctttacctgctggagggctgcgtctgcgaccgcgcgccctcccccaag
ccggcgctgtcggccaaggagccgctggagaaacagcattacttcacggtgaacttcagc
catgagaaccagaaagccttggagctgaggacagaggacgcaaaagattgtgacgaatgg
gtggcagccattgcacatgccagctacaggaccctcgccacagagcatgaggcattaatg
cagaaatacctgcacctgctgcagatcgtggagacagagaagaccgtggccaagcagctt
cggcagcagatcgaggatggggagatcgagatcgagcggctgaaggcagagatcacatcc
ctgctcaaggacaatgagcgcatccagtccacccagactgtcgcccccaacgatgaagac
agcgacatcaagaaaattaagaaggtgcagagcttcctgcggggctggctgtgccggcgg
aagtggaagaccatcatccaggactacatccggtcaccccatgctgacagcatgcgcaag
aggaaccaggtggtgttcagcatgctggaggctgaggctgagtacgtgcagcagctgcac
atccttgtcaacaatttcctgcgcccgctgcggatggccgccagctccaagaagcctccc
atcacacacgacgacgtcagcagcatcttcctgaacagcgaaaccatcatgtttttacat
cagatcttttaccaaggcctgaaggcccgcatctccagctggcccacgctggtcctggct
gacctatttgacatcctgctgcccatgctcaacatctaccaagagttcgtccgcaaccac
cagtacagcctgcagatcctggcccactgcaagcagaaccgtgacttcgacaagctgctg
aagcactacgaggccaagcctgactgcgaggagaggacgctggagaccttcctcacctac
cccatgttccagatccccaggtacatcctgaccctccatgagctcctggcccacacgcct
catgagcacgttgagcgcaacagcctggactacgccaagtccaaactggaggagctgtcc
agaataatgcacgatgaagtaagtgagacggagaacatccggaaaaacctggccatcgag
cgcatgatcatcgaaggctgtgagatcctcctggacaccagccagacctttgtgagacaa
ggttccctcattcaggtgcccatgtctgaaaagggcaagatcaccagggggcgcctgggg
tctctctccctaaagaaagagggcgagcgacagtgcttcctgttttctaagcatctgatt
atctgtaccagaggctctggagggaagcttcacttgaccaagaatggagtcatatccctc
attgactgcactttattggaggagccagaaagcacggaggaggaagccaaaggatccggc
caagacatagatcacttggattttaaaatcggggtggagccaaaggattccccgcccttt
acagtcatcctagtggcctcgtccagacaggagaaggcagcgtggaccagtgacatcagc
cagtgtgtggataacatccgatgcaatgggctcatgatgaacgcatttgaagaaaattcc
aaggtcactgtgccgcagatgatcaagtccgacgcctccttatattgtgatgatgttgac
attcgcttcagcaaaaccatgaactcctgcaaagtgctgcagatccgctacgccagtgtg
gagcggctgctggagaggctgacggacctgcgcttcctgagcatcgacttcctcaacacc
ttcctgcactcctaccgcgtcttcaccaccgccatcgtggtcctggacaagctcattacc
atctacaagaagcctatcagtgccattcctgccaggtcgctggagctcctgtttgccagt
ggccagaacaataagctcctgtacggtgaaccccccaagtccccgcgcgccacccgcaag
ttctcctcgccgccacctctgtccatcaccaagacatcgtcaccgagccgccggcggaag
ctctccctgaacatccccatcatcactggcggcaaggccctggacctggccgccctcagc
tgcaactccaatggctacaccagcatgtactcggccatgtcacccttcagcaaggccacg
ctggacaccagcaagctctatgtgtccagcagcttcaccaacaagattccagatgagggc
gatacgacccctgagaagcccgaagacccttcagcgctcagcaagcagagctcagaagtc
tccatgagagaggagtcagatattgatcaaaaccagagtgatgatggtgatactgaaaca
tcaccaactaaatctccaacaacacccaaatcagtcaaaaacaaaaattcttcagagttc
ccactcttttcctataacaatggagtcgtcatgacctcctgtcgtgaactggacaataac
cgcagtgccttgtcggccgcctctgcctttgccatagcaaccgccggggccaacgagggc
accccaaacaaggagaagtaccggaggatgtccttagccagtgcagggtttcccccagac
cagaggaatggagacaaggagtttgtgatccgcagagcagccaccaatcgtgtcttgaac
gtgctccgccactgggtgtccaagcactctcaggactttgagaccaacgatgagctcaaa
tgcaaggtgatcggcttcctggaagaagtcatgcacgacccggagctcctgacccaggag
cggaaggctgcagccaacatcatcaggactctgacccaggaggacccaggtgacaaccag
atcacgctggaggagatcacgcagatggctgaaggcgtgaaggctgagccctttgaaaac
cactcagccctggagatcgcggagcagctgaccctgctagatcacctcgtcttcaagaag
attccttatgaggagttcttcggacaaggatggatgaaactggaaaagaatgaaaggacc
ccttatatcatgaaaaccactaagcacttcaatgacatcagtaacttgattgcttcagaa
atcatccgcaatgaggacatcaacgccagggtgagcgccatcgagaagtgggtggccgta
gctgacatatgccgctgcctccacaactacaatgccgtactggagatcacctcgtccatg
aaccgcagtgcaatcttccggctcaaaaagacgtggctcaaagtctctaagcagactaaa
gctttgattgataagctccaaaagcttgtgtcatctgagggcagatttaagaatctcaga
gaagctctgaaaaattgtgacccaccctgtgtcccttacctggggatgtacctcaccgac
ctggccttcatcgaggaggggacgcccaattacacggaagacggcctggtcaacttctcc
aagatgaggatgatatcccatattatccgagagattcgccagtttcaacaaactgcctac
aaaatagagcaccaagcaaaggtaacgcaatatttactggaccaatcttttgtaatggat
gaagaaagcctctacgagtcttctctccgaatagaaccaaaactccccacctga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (7)   
   UniGene (1)   
   HGNC (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (5)   
   RefSeq(pep) (3)   
DNA sequence (33)   
   RefSeq(nuc) (3)   
   GenBank (15)   
   EMBL (15)   
Protein domain (6)   
   Pfam (6)   
All databases (65)   

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