KEGG   Homo sapiens (human): 5970Help
Entry
5970              CDS       T01001                                 

Gene name
RELA, NFKB3, p65
Definition
v-rel avian reticuloendotheliosis viral oncogene homolog A
Orthology
K04735  
transcription factor p65
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Ras signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
PI3K-Akt signaling pathway
Apoptosis
Osteoclast differentiation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Cytosolic DNA-sensing pathway
T cell receptor signaling pathway
B cell receptor signaling pathway
TNF signaling pathway
Neurotrophin signaling pathway
Prolactin signaling pathway
Adipocytokine signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Cocaine addiction
Epithelial cell signaling in Helicobacter pylori infection
Shigellosis
Salmonella infection
Pertussis
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Tuberculosis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Transcriptional misregulation in cancer
Viral carcinogenesis
Pancreatic cancer
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    5970 (RELA)
   04010 MAPK signaling pathway
    5970 (RELA)
   04064 NF-kappa B signaling pathway
    5970 (RELA)
   04668 TNF signaling pathway
    5970 (RELA)
   04066 HIF-1 signaling pathway
    5970 (RELA)
   04024 cAMP signaling pathway
    5970 (RELA)
   04151 PI3K-Akt signaling pathway
    5970 (RELA)
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    5970 (RELA)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    5970 (RELA)
   04621 NOD-like receptor signaling pathway
    5970 (RELA)
   04622 RIG-I-like receptor signaling pathway
    5970 (RELA)
   04623 Cytosolic DNA-sensing pathway
    5970 (RELA)
   04660 T cell receptor signaling pathway
    5970 (RELA)
   04662 B cell receptor signaling pathway
    5970 (RELA)
   04062 Chemokine signaling pathway
    5970 (RELA)
  Endocrine system
   04920 Adipocytokine signaling pathway
    5970 (RELA)
   04917 Prolactin signaling pathway
    5970 (RELA)
  Nervous system
   04722 Neurotrophin signaling pathway
    5970 (RELA)
  Development
   04380 Osteoclast differentiation
    5970 (RELA)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    5970 (RELA)
   05202 Transcriptional misregulation in cancers
    5970 (RELA)
   05203 Viral carcinogenesis
    5970 (RELA)
   05212 Pancreatic cancer
    5970 (RELA)
   05221 Acute myeloid leukemia
    5970 (RELA)
   05220 Chronic myeloid leukemia
    5970 (RELA)
   05215 Prostate cancer
    5970 (RELA)
   05222 Small cell lung cancer
    5970 (RELA)
  Immune diseases
   05321 Inflammatiory bowel disease (IBD)
    5970 (RELA)
  Substance dependence
   05030 Cocaine addiction
    5970 (RELA)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    5970 (RELA)
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    5970 (RELA)
   05132 Salmonella infection
    5970 (RELA)
   05131 Shigellosis
    5970 (RELA)
   05133 Pertussis
    5970 (RELA)
   05134 Legionellosis
    5970 (RELA)
   05152 Tuberculosis
    5970 (RELA)
   05166 HTLV-I infection
    5970 (RELA)
   05162 Measles
    5970 (RELA)
   05164 Influenza A
    5970 (RELA)
   05161 Hepatitis B
    5970 (RELA)
   05160 Hepatitis C
    5970 (RELA)
   05168 Herpes simplex infection
    5970 (RELA)
   05169 Epstein-Barr virus infection
    5970 (RELA)
   05146 Amoebiasis
    5970 (RELA)
   05145 Toxoplasmosis
    5970 (RELA)
   05140 Leishmaniasis
    5970 (RELA)
   05142 Chagas disease (American trypanosomiasis)
    5970 (RELA)
Transcription factors [BR:hsa03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    5970 (RELA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
11q13
AA seq 548 aa AA seqDB search
MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
VKKRDLEQAISQRIQTNNNPFQEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPI
FDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQAD
VHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRK
RTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEF
PTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAP
PAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIP
VAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFS
ALLSQISS
NT seq 1647 nt NT seq  +upstreamnt  +downstreamnt
atggacgaactgttccccctcatcttcccggcagagccagcccaggcctctggcccctat
gtggagatcattgagcagcccaagcagcggggcatgcgcttccgctacaagtgcgagggg
cgctccgcgggcagcatcccaggcgagaggagcacagataccaccaagacccaccccacc
atcaagatcaatggctacacaggaccagggacagtgcgcatctccctggtcaccaaggac
cctcctcaccggcctcacccccacgagcttgtaggaaaggactgccgggatggcttctat
gaggctgagctctgcccggaccgctgcatccacagtttccagaacctgggaatccagtgt
gtgaagaagcgggacctggagcaggctatcagtcagcgcatccagaccaacaacaacccc
ttccaagaagagcagcgtggggactacgacctgaatgctgtgcggctctgcttccaggtg
acagtgcgggacccatcaggcaggcccctccgcctgccgcctgtcctttctcatcccatc
tttgacaatcgtgcccccaacactgccgagctcaagatctgccgagtgaaccgaaactct
ggcagctgcctcggtggggatgagatcttcctactgtgtgacaaggtgcagaaagaggac
attgaggtgtatttcacgggaccaggctgggaggcccgaggctccttttcgcaagctgat
gtgcaccgacaagtggccattgtgttccggacccctccctacgcagaccccagcctgcag
gctcctgtgcgtgtctccatgcagctgcggcggccttccgaccgggagctcagtgagccc
atggaattccagtacctgccagatacagacgatcgtcaccggattgaggagaaacgtaaa
aggacatatgagaccttcaagagcatcatgaagaagagtcctttcagcggacccaccgac
ccccggcctccacctcgacgcattgctgtgccttcccgcagctcagcttctgtccccaag
ccagcaccccagccctatccctttacgtcatccctgagcaccatcaactatgatgagttt
cccaccatggtgtttccttctgggcagatcagccaggcctcggccttggccccggcccct
ccccaagtcctgccccaggctccagcccctgcccctgctccagccatggtatcagctctg
gcccaggccccagcccctgtcccagtcctagccccaggccctcctcaggctgtggcccca
cctgcccccaagcccacccaggctggggaaggaacgctgtcagaggccctgctgcagctg
cagtttgatgatgaagacctgggggccttgcttggcaacagcacagacccagctgtgttc
acagacctggcatccgtcgacaactccgagtttcagcagctgctgaaccagggcatacct
gtggccccccacacaactgagcccatgctgatggagtaccctgaggctataactcgccta
gtgacaggggcccagaggccccccgacccagctcctgctccactgggggccccggggctc
cccaatggcctcctttcaggagatgaagacttctcctccattgcggacatggacttctca
gccctgctgagtcagatcagctcctaa

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